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Index > Protein center > ADAM18(Gene name) > Human
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  • ADAM18 (Gene name),
  • Disintegrin and metalloproteinase domain-containing protein 18 (Protein name ),  ADA18_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ADAM18(UNQ858/PRO1867;TMDC3);
    Protein name:
    Disintegrin and metalloproteinase domain-containing protein 18(ADAM 18);
    Alternative:
    Transmembrane metalloproteinase-like, disintegrin-like, and cysteine-rich protein III(tMDC III);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Sperm surface membrane protein that may be involved in spermatogenesis and fertilization. This is a non catalytic metalloprotease-like protein.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    739
    Sequence:
    50:
    MFLLLALLTE | LGRLQAHEGS | EGIFLHVTVP | RKIKSNDSEV | SERKMIYIIT | 
    100:
    IDGQPYTLHL | GKQSFLPQNF | LVYTYNETGS | LHSVSPYFMM | HCHYQGYAAE | 
    150:
    FPNSFVTLSI | CSGLRGFLQF | ENISYGIEPV | ESSARFEHII | YQMKNNDPNV | 
    200:
    SILAVNYSHI | WQKDQPYKVP | LNSQIKNLSK | LLPQYLEIYI | IVEKALYDYM | 
    250:
    GSEMMAVTQK | IVQVIGLVNT | MFTQFKLTVI | LSSLELWSNE | NQISTSGDAD | 
    300:
    DILQRFLAWK | RDYLILRPHD | IAYLLVYRKH | PKYVGATFPG | TVCNKSYDAG | 
    350:
    IAMYPDAIGL | EGFSVIIAQL | LGLNVGLTYD | DITQCFCLRA | TCIMNHEAVS | 
    400:
    ASGRKIFSNC | SMHDYRYFVS | KFETKCLQKL | SNLQPLHQNQ | PVCGNGILES | 
    450:
    NEECDCGNKN | ECQFKKCCDY | NTCKLKGSVK | CGSGPCCTSK | CELSIAGTPC | 
    500:
    RKSIDPECDF | TEYCNGTSSN | CVPDTYALNG | RLCKLGTAYC | YNGQCQTTDN | 
    550:
    QCAKIFGKGA | QGAPFACFKE | VNSLHERSEN | CGFKNSQPLP | CERKDVLCGK | 
    600:
    LACVQPHKNA | NKSDAQSTVY | SYIQDHVCVS | IATGSSMRSD | GTDNAYVADG | 
    650:
    TMCGPEMYCV | NKTCRKVHLM | GYNCNATTKC | KGKGICNNFG | NCQCFPGHRP | 
    700:
    PDCKFQFGSP | GGSIDDGNFQ | KSGDFYTEKG | YNTHWNNWFI | LSFCIFLPFF | 
    739:
    IVFTTVIFKR | NEISKSCNRE | NAEYNRNSSV | VSESDDVGH
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human ADAM 18
    ELISA Kit for Human ADAM 18
    ELISA Kit for Human ADAM 18
    CLIA Kit for Human ADAM 18
    CLIA Kit for Human ADAM 18
    CLIA Kit for Human ADAM 18
    Polyclonal Antibody for Human ADAM 18
    Polyclonal Antibody for Human ADAM 18
    Polyclonal Antibody for Human ADAM 18
    Monoclonal Antibody for Human ADAM 18
    Monoclonal Antibody for Human ADAM 18
    Monoclonal Antibody for Human ADAM 18
    Protein for Human ADAM 18
    Protein for Human ADAM 18
    Protein for Human ADAM 18

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    Precision
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    Linearity
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    References
    1. 1.
      "Nucleotide sequence of the human tMDC III sperm surface protein transcript."
      Hall L. , Frayne J. , Dimsey E.A.
      Submitted (1999-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Testis.
    2. 2.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Testis.
    4. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
      tissue: Testis.
    5. 6.
      "Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma."
      Wei X. , Moncada-Pazos A. , Cal S. , Soria-Valles C. , Gartner J. , Rudloff U. , Lin J.C. , Rosenberg S.A. , Lopez-Otin C. , Samuels Y.
      Hum. Mutat.32:E2148-E2175(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SER-170; GLY-284; ILE-344; LYS-362 AND LEU-536
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