ADAM19 ELISA Kit for Human(Homo sapiens) | EIAab.comADAM19 ELISA Kit for Human(Homo sapiens) | EIAab.com

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ADAM19 (Gene name),

Disintegrin and metalloproteinase domain-containing protein 19 (Protein name ), ADA19_HUMAN from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Gene name:

ADAM19(FKSG34;MLTNB);

Protein name:

Disintegrin and metalloproteinase domain-containing protein 19(ADAM 19);

Alternative:

Metalloprotease and disintegrin dendritic antigen marker(MADDAM);Meltrin-beta;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with SH3PXD2A.

Function:

Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

955

Sequence:

50:

MPGGAGAARL | CLLAFALQPL | RPRAAREPGW | TRGSEEGSPK | LQHELIIPQW |

100:

KTSESPVREK | HPLKAELRVM | AEGRELILDL | EKNEQLFAPS | YTETHYTSSG |

150:

NPQTTTRKLE | DHCFYHGTVR | ETELSSVTLS | TCRGIRGLIT | VSSNLSYVIE |

200:

PLPDSKGQHL | IYRSEHLKPP | PGNCGFEHSK | PTTRDWALQF | TQQTKKRPRR |

250:

MKREDLNSMK | YVELYLVADY | LEFQKNRRDQ | DATKHKLIEI | ANYVDKFYRS |

300:

LNIRIALVGL | EVWTHGNMCE | VSENPYSTLW | SFLSWRRKLL | AQKYHDNAQL |

350:

ITGMSFHGTT | IGLAPLMAMC | SVYQSGGVNM | DHSENAIGVA | ATMAHEMGHN |

400:

FGMTHDSADC | CSASAADGGC | IMAAATGHPF | PKVFNGCNRR | ELDRYLQSGG |

450:

GMCLSNMPDT | RMLYGGRRCG | NGYLEDGEEC | DCGEEEECNN | PCCNASNCTL |

500:

RPGAECAHGS | CCHQCKLLAP | GTLCREQARQ | CDLPEFCTGK | SPHCPTNFYQ |

550:

MDGTPCEGGQ | AYCYNGMCLT | YQEQCQQLWG | PGARPAPDLC | FEKVNVAGDT |

600:

FGNCGKDMNG | EHRKCNMRDA | KCGKIQCQSS | EARPLESNAV | PIDTTIIMNG |

650:

RQIQCRGTHV | YRGPEEEGDM | LDPGLVMTGT | KCGYNHICFE | GQCRNTSFFE |

700:

TEGCGKKCNG | HGVCNNNQNC | HCLPGWAPPF | CNTPGHGGSI | DSGPMPPESV |

750:

GPVVAGVLVA | ILVLAVLMLM | YYCCRQNNKL | GQLKPSALPS | KLRQQFSCPF |

800:

RVSQNSGTGH | ANPTFKLQTP | QGKRKVINTP | EILRKPSQPP | PRPPPDYLRG |

850:

GSPPAPLPAH | LSRAARNSPG | PGSQIERTES | SRRPPPSRPI | PPAPNCIVSQ |

900:

DFSRPRPPQK | ALPANPVPGR | RSLPRPGGAS | PLRPPGAGPQ | QSRPLAALAP |

950:

KVSPREALKV | KAGTRGLQGG | RCRVEKTKQF | MLLVVWTELP | EQKPRAKHSC |

955:

FLVPA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Pfam:

STRING:

9606.ENSP00000257527

SMR:

KEGG:

String:

MIM:

Uniprot:

FOR

ELISA Kit for Human ADAM 19

ELISA Kit for Human ADAM 19

CLIA Kit for Human ADAM 19

CLIA Kit for Human ADAM 19

Polyclonal Antibody for Human ADAM 19

Polyclonal Antibody for Human ADAM 19

Monoclonal Antibody for Human ADAM 19

Monoclonal Antibody for Human ADAM 19

Protein for Human ADAM 19

Protein for Human ADAM 19

R&D Technical Data

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Precision

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Recovery

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Linearity

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References

1.

"Identification of FKSG34, a novel human gene encoding for metalloprotease-disintegrin meltrin beta."
Wang Y.-G. , Gong L.
Submitted (2000-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM A)
2.

"Molecular cloning and characterization of a human metalloprotease disintegrin a novel marker for dendritic cell differentiation."
Fritsche J. , Moser M. , Faust S. , Peuker A. , Buettner R. , Andreesen R. , Kreutz M.
Blood96:732-739(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM B);VARIANT SER-4
tissue: Lymph node.
3.

"Expression and enzymatic activity of human disintegrin and metalloproteinase ADAM19/meltrin beta."
Wei P. , Zhao Y.-G. , Zhuang L. , Ruben S. , Sang Q.-X.A.
Biochem. Biophys. Res. Commun.280:744-755(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM B)
tissue: Dendritic cell.
4.

"The DNA sequence and comparative analysis of human chromosome 5."
Schmutz J. , Martin J. , Terry A. , Couronne O. , Grimwood J. , Lowry S. , Gordon L.A. , Scott D. , Xie G. , Huang W. , Hellsten U. , Tran-Gyamfi M. , She X. , Prabhakar S. , Aerts A. , Altherr M. , Bajorek E. , Black S. , more...
Nature431:268-274(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"Partial sequence of Homo sapiens ADAM19."
Xu R. , Cai J. , Ying B. , Wang F. , Xu T. , Zhao S. , Li C.
Submitted (1999-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 99-955 (ISOFORM A)
6.

"The adaptor protein fish associates with members of the ADAMs family and localizes to podosomes of Src-transformed cells."
Abram C.L. , Seals D.F. , Pass I. , Salinsky D. , Maurer L. , Roth T.M. , Courtneidge S.A.
J. Biol. Chem.278:16844-16851(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SH3PXD2A
7.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] GLN-133 AND THR-298
8.

"Core signaling pathways in human pancreatic cancers revealed by global genomic analyses."
Jones S. , Zhang X. , Parsons D.W. , Lin J.C. , Leary R.J. , Angenendt P. , Mankoo P. , Carter H. , Kamiyama H. , Jimeno A. , Hong S.M. , Fu B. , Lin M.T. , Calhoun E.S. , Kamiyama M. , Walter K. , Nikolskaya T. , Nikolsky Y. , more...
Science321:1801-1806(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] GLN-609

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