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Index > Protein center > Adam19(Gene name) > Mouse
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  • Adam19 (Gene name),
  • Disintegrin and metalloproteinase domain-containing protein 19 (Protein name ),  ADA19_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Adam19(Mltnb);
    Protein name:
    Disintegrin and metalloproteinase domain-containing protein 19(ADAM 19);
    Alternative:
    Meltrin-beta;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with SH3PXD2A.
    Function:
    Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    920
    Sequence:
    50:
    MPGRAGVARF | CLLALALQLH | WPLAACEPGW | TTRGSQEGSP | PLQHELIIPQ | 
    100:
    WRTSESPGRG | KHPLRAELRV | MAEGRELILD | LEKNEHLFAP | AYTETCYTAS | 
    150:
    GNPQTSTLKS | EDHCFYHGTV | RDVDESSVTL | STCRGIRGLI | IVRSNLSYII | 
    200:
    EPVPNSDSQH | RIYRSEHLTL | PPGNCGFEHS | GPTSKDWALQ | FTHQTKKQPR | 
    250:
    RMKREDLHSM | KYVELYLVAD | YAEFQKNRHD | QDATKRKLME | IANYVDKFYR | 
    300:
    SLNIRIALVG | LEVWTHGDKC | EVSENPYSTL | WSFLSWRRKL | LAQKSHDNAQ | 
    350:
    LITGRSFQGT | TIGLAPLMAM | CSVYQSGGVS | MDHSENAIGV | ASTVAHEIGH | 
    400:
    NFGMSHDSAH | CCSASAADGG | CIMAAATGHP | FPKVFSWCNR | KELDRYLQTG | 
    450:
    GGMCLSNMPD | TRTLYGGRRC | GNGYLEDGEE | CDCGEEEECK | NPCCNASNCT | 
    500:
    LKEGAECAHG | SCCHQCKLVA | PGTQCREQVR | QCDLPEFCTG | KSPHCPTNYY | 
    550:
    QMDGTPCEGG | QAYCYNGMCL | TYQEQCQQLW | GPGARPALDL | CFERVNAAGD | 
    600:
    TYGNCGKGLN | GQYRKCSPRD | AKCGKIQCQS | TQARPLESNA | VSIDTTITLN | 
    650:
    GRRIHCRGTH | VYRGPEEEEG | EGDMLDPGLV | MTGTKCGHNH | ICFEGQCRNT | 
    700:
    SFFETEGCGK | KCNGHGVCNN | NKNCHCFPGW | SPPFCNTPGD | GGSVDSGPLP | 
    750:
    PKSVGPVIAG | VFSALFVLAV | LVLLCHCYRQ | SHKLGKPSAL | PFKLRHQFSC | 
    800:
    PFRVSQSGGT | GHANPTFKLQ | TPQGKRKVTN | TPESLRKPSH | PPPRPPPDYL | 
    850:
    RVESPPAPLP | AHLNRAAGSS | PEAGARIERK | ESARRPPPSR | PMPPAPNCLL | 
    900:
    SQDFSRPRPP | QKALPANPVP | GQRTGPRSGG | TSLLQPPTSG | PQPPRPPAVP | 
    920:
    VPKLPEYRSQ | RVGAIISSKI | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    String:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse ADAM 19
    ELISA Kit for Mouse ADAM 19
    CLIA Kit for Mouse ADAM 19
    CLIA Kit for Mouse ADAM 19
    Polyclonal Antibody for Mouse ADAM 19
    Polyclonal Antibody for Mouse ADAM 19
    Monoclonal Antibody for Mouse ADAM 19
    Monoclonal Antibody for Mouse ADAM 19
    Protein for Mouse ADAM 19
    Protein for Mouse ADAM 19

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Cloning and initial characterization of mouse meltrin beta and analysis of the expression of four metalloprotease-disintegrins in bone cells."
      Inoue D. , Reid M.S. , Lum L. , Kraetzschmar J. , Weskamp G. , Myung Y.M. , Baron R. , Blobel C.P.
      J. Biol. Chem.273:4180-4187(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Myoblast.
    2. 2.
      "Spatially- and temporally-restricted expression of meltrin alpha (ADAM12) and beta (ADAM19) in mouse embryo."
      Kurisaki T. , Masuda A. , Osumi N. , Nabeshima Y. , Fujisawa-Sehara A.
      Mech. Dev.73:211-215(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];DEVELOPMENTAL STAGE
      tissue: Myoblast.
    3. 3.
      "A metalloprotease-disintegrin participating in myoblast fusion."
      Yagami-Hiromasa T. , Sato T. , Kurisaki T. , Kamijo K. , Nabeshima Y. , Fujisawa-Sehara A.
      Nature377:652-656(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 429-578
      tissue: Embryonic fibroblast.
    4. 4.
      "Roles of Meltrin beta /ADAM19 in the processing of neuregulin."
      Shirakabe K. , Wakatsuki S. , Kurisaki T. , Fujisawa-Sehara A.
      J. Biol. Chem.276:9352-9358(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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