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Index > Protein center > Adam2(Gene name) > Mouse
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  • Adam2 (Gene name),
  • Disintegrin and metalloproteinase domain-containing protein 2 (Protein name ),  ADAM2_MOUSE from NCBI database.
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  • Gene name:
    Adam2(Ftnb);
    Protein name:
    Disintegrin and metalloproteinase domain-containing protein 2(ADAM 2);
    Alternative:
    PH-30(PH30);Fertilin subunit beta;PH30-beta;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterodimer with ADAM1/fertilin subunit alpha.
    Function:
    Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    735
    Sequence:
    50:
    MWLILLLLSG | LSELGGLSQS | QTEGTREKLH | VQVTVPEKIR | SVTSNGYETQ | 
    100:
    VTYNLKIEGK | TYTLDLMQKP | FLPPNFRVYS | YDNAGIMRSL | EQKFQNICYF | 
    150:
    QGYIEGYPNS | MVIVSTCTGL | RGFLQFGNVS | YGIEPLESSS | GFEHVIYQVE | 
    200:
    PEKGGALLYA | EKDIDLRDSQ | YKIRSIKPQR | IVSHYLEIHI | VVEKQMFEHI | 
    250:
    GADTAIVTQK | IFQLIGLANA | IFAPFNLTVI | LSSLEFWMDE | NKILTTGDAN | 
    300:
    KLLYRFLKWK | QSYLVLRPHD | MAFLLVYRNT | TDYVGATYQG | KMCDKNYAGG | 
    350:
    VALHPKAVTL | ESLAIILVQL | LSLSMGLAYD | DVNKCQCGVP | VCVMNPEAPH | 
    400:
    SSGVRAFSNC | SMEDFSKFIT | SQSSHCLQNQ | PRLQPSYKMA | VCGNGEVEED | 
    450:
    EICDCGKKGC | AEMPPPCCNP | DTCKLSDGSE | CSSGICCNSC | KLKRKGEVCR | 
    500:
    LAQDECDVTE | YCNGTSEVCE | DFFVQNGHPC | DNRKWICING | TCQSGEQQCQ | 
    550:
    DLFGIDAGFG | SSECFWELNS | KSDISGSCGI | SAGGYKECPP | NDRMCGKIIC | 
    600:
    KYQSENILKL | RSATVIYANI | SGHVCVSLEY | PQGHNESQKM | WVRDGTVCGS | 
    650:
    NKVCQNQKCV | ADTFLGYDCN | LEKCNHHGVC | NNKKNCHCDP | TYLPPDCKRM | 
    700:
    KDSYPGGSID | SGNKERAEPI | PVRPYIASAY | RSKSPRWPFF | LIIPFYVVIL | 
    735:
    VLIGMLVKVY | SQRMKWRMDD | FSSEEQFESE | SESKD
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    UniGene:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse ADAM 2
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    ELISA Kit for Mouse ADAM 2
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    CLIA Kit for Mouse ADAM 2
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    96T
    CLIA Kit for Mouse ADAM 2
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    U14287h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse ADAM 2
    Cat.:
    U14287m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse ADAM 2
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse ADAM 2
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    U14287r
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    Packing:
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    Polyclonal Antibody for Mouse ADAM 2
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    P14287Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ADAM 2
    Cat.:
    P14287Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse ADAM 2
    Polyclonal Antibody for Mouse ADAM 2
    Polyclonal Antibody for Mouse ADAM 2
    Cat.:
    P14287Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse ADAM 2
    Monoclonal Antibody for Mouse ADAM 2
    Monoclonal Antibody for Mouse ADAM 2
    Monoclonal Antibody for Mouse ADAM 2
    Monoclonal Antibody for Mouse ADAM 2
    Protein for Mouse ADAM 2
    Protein for Mouse ADAM 2
    Protein for Mouse ADAM 2
    Protein for Mouse ADAM 2
    Protein for Mouse ADAM 2

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    References
    1. 1.
      "Mouse sperm-egg plasma membrane interactions: analysis of roles of egg integrins and the mouse sperm homologue of PH-30 (fertilin) beta."
      Evans J.P. , Schultz R.M. , Kopf G.S.
      J. Cell Sci.108:3267-3278(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Testis.
    2. 2.
      Gupta S.K. , Alves K. , Palladino L.O. , Mark G.E. , Hollis G.F.
      Submitted (1995-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Testis.
    4. 4.
      "ADAM, a widely distributed and developmentally regulated gene family encoding membrane proteins with a disintegrin and metalloprotease domain."
      Wolfsberg T.G. , Straight P.D. , Gerena R.L. , Huovila A.-P. , Primakoff P. , Myles D.G. , White J.M.
      Dev. Biol.169:378-383(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 17-735
      tissue: Testis.
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