Gene name:
AGRP (AGRT;ART) ;
Protein name:
Agouti-related protein ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with melanocortin receptors MC3R, MC4R and MC5R.
Function:
Plays a role in weight homeostasis. Plays a role in the central control of feeding. Reduces food intake. Inhibits cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Acts primarily on MC3R and MC4R. Has very low activity with MC5R.
Subcellular Location:
Secreted
Golgi apparatus lumen
Protein Attributes:
50:
MLTAAVLSCA | LLLALPATRG | AQMGLAPMEG | IRRPDQALLP | ELPGLGLRAP |
100:
LKKTTAEQAE | EDLLQEAQAL | AEVLDLQDRE | PRSSRRCVRL | HESCLGQQVP |
132:
CCDPCATCYC | RFFNAFCYCR | KLGTAMNPCS | RT
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Mouse
Pig
ELISA Kit for Human Agouti-related protein
ELISA Kit for Human Agouti-related protein
ELISA Kit for Human Agouti-related protein
ELISA Kit for Human Agouti-related protein
CLIA Kit for Human Agouti-related protein
CLIA Kit for Human Agouti-related protein
CLIA Kit for Human Agouti-related protein
CLIA Kit for Human Agouti-related protein
Polyclonal Antibody for Human Agouti-related protein
Polyclonal Antibody for Human Agouti-related protein
Polyclonal Antibody for Human Agouti-related protein
Polyclonal Antibody for Human Agouti-related protein
Monoclonal Antibody for Human Agouti-related protein
Monoclonal Antibody for Human Agouti-related protein
Monoclonal Antibody for Human Agouti-related protein
Monoclonal Antibody for Human Agouti-related protein
Protein for Human Agouti-related protein
Protein for Human Agouti-related protein
Protein for Human Agouti-related protein
Protein for Human Agouti-related protein
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Adrenal gland .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT THR-67
4.
"Association between an agouti-related protein gene polymorphism and anorexia nervosa."
Vink T.
,
Hinney A.
,
van Elburg A.A.
,
van Goozen S.H.
,
Sandkuijl L.A.
,
Sinke R.J.
,
Herpertz-Dahlmann B.M.
,
Hebebrand J.
,
Remschmidt H.
,
van Engeland H.
,
Adan R.A.
Mol. Psychiatry6:325-328(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DISULFIDE BONDS
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH MC3R; MC4R AND MC5R
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION AS INVERSE AGONIST FOR MC3R AND MC4R
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION IN MC3R AND MC4R ENDOCYTOSIS
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 87-132;FUNCTION;CIRCULAR DICHROISM;DISULFIDE BONDS;MUTAGENESIS OF ARG-111
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 87-132;DOMAIN;DISULFIDE BONDS
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 87-120
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT THR-67;POSSIBLE ASSOCIATION WITH OBESITY
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CHARACTERIZATION OF VARIANT THR-67;SUBCELLULAR LOCATION;FUNCTION