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Index > Protein center > APOB(Gene name) > Human
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  • APOB (Gene name),
  • Apolipoprotein B-100 (Protein name ),  APOB_HUMAN from NCBI database.
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  • Gene name:
    APOB;
    Protein name:
    Apolipoprotein B-100(Apo B-100);
    Alternative:
    Apolipoprotein B;
    Organism:
    APOB (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    4563
    Sequence:
    50:
    MDPPRPALLA | LLALPALLLL | LLAGARAEEE | MLENVSLVCP | KDATRFKHLR | 
    100:
    KYTYNYEAES | SSGVPGTADS | RSATRINCKV | ELEVPQLCSF | ILKTSQCTLK | 
    150:
    EVYGFNPEGK | ALLKKTKNSE | EFAAAMSRYE | LKLAIPEGKQ | VFLYPEKDEP | 
    200:
    TYILNIKRGI | ISALLVPPET | EEAKQVLFLD | TVYGNCSTHF | TVKTRKGNVA | 
    250:
    TEISTERDLG | QCDRFKPIRT | GISPLALIKG | MTRPLSTLIS | SSQSCQYTLD | 
    300:
    AKRKHVAEAI | CKEQHLFLPF | SYKNKYGMVA | QVTQTLKLED | TPKINSRFFG | 
    350:
    EGTKKMGLAF | ESTKSTSPPK | QAEAVLKTLQ | ELKKLTISEQ | NIQRANLFNK | 
    400:
    LVTELRGLSD | EAVTSLLPQL | IEVSSPITLQ | ALVQCGQPQC | STHILQWLKR | 
    450:
    VHANPLLIDV | VTYLVALIPE | PSAQQLREIF | NMARDQRSRA | TLYALSHAVN | 
    500:
    NYHKTNPTGT | QELLDIANYL | MEQIQDDCTG | DEDYTYLILR | VIGNMGQTME | 
    550:
    QLTPELKSSI | LKCVQSTKPS | LMIQKAAIQA | LRKMEPKDKD | QEVLLQTFLD | 
    600:
    DASPGDKRLA | AYLMLMRSPS | QADINKIVQI | LPWEQNEQVK | NFVASHIANI | 
    650:
    LNSEELDIQD | LKKLVKEALK | ESQLPTVMDF | RKFSRNYQLY | KSVSLPSLDP | 
    700:
    ASAKIEGNLI | FDPNNYLPKE | SMLKTTLTAF | GFASADLIEI | GLEGKGFEPT | 
    750:
    LEALFGKQGF | FPDSVNKALY | WVNGQVPDGV | SKVLVDHFGY | TKDDKHEQDM | 
    800:
    VNGIMLSVEK | LIKDLKSKEV | PEARAYLRIL | GEELGFASLH | DLQLLGKLLL | 
    850:
    MGARTLQGIP | QMIGEVIRKG | SKNDFFLHYI | FMENAFELPT | GAGLQLQISS | 
    900:
    SGVIAPGAKA | GVKLEVANMQ | AELVAKPSVS | VEFVTNMGII | IPDFARSGVQ | 
    950:
    MNTNFFHESG | LEAHVALKAG | KLKFIIPSPK | RPVKLLSGGN | TLHLVSTTKT | 
    1000:
    EVIPPLIENR | QSWSVCKQVF | PGLNYCTSGA | YSNASSTDSA | SYYPLTGDTR | 
    1050:
    LELELRPTGE | IEQYSVSATY | ELQREDRALV | DTLKFVTQAE | GAKQTEATMT | 
    1100:
    FKYNRQSMTL | SSEVQIPDFD | VDLGTILRVN | DESTEGKTSY | RLTLDIQNKK | 
    1150:
    ITEVALMGHL | SCDTKEERKI | KGVISIPRLQ | AEARSEILAH | WSPAKLLLQM | 
    1200:
    DSSATAYGST | VSKRVAWHYD | EEKIEFEWNT | GTNVDTKKMT | SNFPVDLSDY | 
    1250:
    PKSLHMYANR | LLDHRVPQTD | MTFRHVGSKL | IVAMSSWLQK | ASGSLPYTQT | 
    1300:
    LQDHLNSLKE | FNLQNMGLPD | FHIPENLFLK | SDGRVKYTLN | KNSLKIEIPL | 
    1350:
    PFGGKSSRDL | KMLETVRTPA | LHFKSVGFHL | PSREFQVPTF | TIPKLYQLQV | 
    1400:
    PLLGVLDLST | NVYSNLYNWS | ASYSGGNTST | DHFSLRARYH | MKADSVVDLL | 
    1450:
    SYNVQGSGET | TYDHKNTFTL | SYDGSLRHKF | LDSNIKFSHV | EKLGNNPVSK | 
    1500:
    GLLIFDASSS | WGPQMSASVH | LDSKKKQHLF | VKEVKIDGQF | RVSSFYAKGT | 
    1550:
    YGLSCQRDPN | TGRLNGESNL | RFNSSYLQGT | NQITGRYEDG | TLSLTSTSDL | 
    1600:
    QSGIIKNTAS | LKYENYELTL | KSDTNGKYKN | FATSNKMDMT | FSKQNALLRS | 
    1650:
    EYQADYESLR | FFSLLSGSLN | SHGLELNADI | LGTDKINSGA | HKATLRIGQD | 
    1700:
    GISTSATTNL | KCSLLVLENE | LNAELGLSGA | SMKLTTNGRF | REHNAKFSLD | 
    1750:
    GKAALTELSL | GSAYQAMILG | VDSKNIFNFK | VSQEGLKLSN | DMMGSYAEMK | 
    1800:
    FDHTNSLNIA | GLSLDFSSKL | DNIYSSDKFY | KQTVNLQLQP | YSLVTTLNSD | 
    1850:
    LKYNALDLTN | NGKLRLEPLK | LHVAGNLKGA | YQNNEIKHIY | AISSAALSAS | 
    1900:
    YKADTVAKVQ | GVEFSHRLNT | DIAGLASAID | MSTNYNSDSL | HFSNVFRSVM | 
    1950:
    APFTMTIDAH | TNGNGKLALW | GEHTGQLYSK | FLLKAEPLAF | TFSHDYKGST | 
    2000:
    SHHLVSRKSI | SAALEHKVSA | LLTPAEQTGT | WKLKTQFNNN | EYSQDLDAYN | 
    2050:
    TKDKIGVELT | GRTLADLTLL | DSPIKVPLLL | SEPINIIDAL | EMRDAVEKPQ | 
    2100:
    EFTIVAFVKY | DKNQDVHSIN | LPFFETLQEY | FERNRQTIIV | VLENVQRNLK | 
    2150:
    HINIDQFVRK | YRAALGKLPQ | QANDYLNSFN | WERQVSHAKE | KLTALTKKYR | 
    2200:
    ITENDIQIAL | DDAKINFNEK | LSQLQTYMIQ | FDQYIKDSYD | LHDLKIAIAN | 
    2250:
    IIDEIIEKLK | SLDEHYHIRV | NLVKTIHDLH | LFIENIDFNK | SGSSTASWIQ | 
    2300:
    NVDTKYQIRI | QIQEKLQQLK | RHIQNIDIQH | LAGKLKQHIE | AIDVRVLLDQ | 
    2350:
    LGTTISFERI | NDILEHVKHF | VINLIGDFEV | AEKINAFRAK | VHELIERYEV | 
    2400:
    DQQIQVLMDK | LVELAHQYKL | KETIQKLSNV | LQQVKIKDYF | EKLVGFIDDA | 
    2450:
    VKKLNELSFK | TFIEDVNKFL | DMLIKKLKSF | DYHQFVDETN | DKIREVTQRL | 
    2500:
    NGEIQALELP | QKAEALKLFL | EETKATVAVY | LESLQDTKIT | LIINWLQEAL | 
    2550:
    SSASLAHMKA | KFRETLEDTR | DRMYQMDIQQ | ELQRYLSLVG | QVYSTLVTYI | 
    2600:
    SDWWTLAAKN | LTDFAEQYSI | QDWAKRMKAL | VEQGFTVPEI | KTILGTMPAF | 
    2650:
    EVSLQALQKA | TFQTPDFIVP | LTDLRIPSVQ | INFKDLKNIK | IPSRFSTPEF | 
    2700:
    TILNTFHIPS | FTIDFVEMKV | KIIRTIDQML | NSELQWPVPD | IYLRDLKVED | 
    2750:
    IPLARITLPD | FRLPEIAIPE | FIIPTLNLND | FQVPDLHIPE | FQLPHISHTI | 
    2800:
    EVPTFGKLYS | ILKIQSPLFT | LDANADIGNG | TTSANEAGIA | ASITAKGESK | 
    2850:
    LEVLNFDFQA | NAQLSNPKIN | PLALKESVKF | SSKYLRTEHG | SEMLFFGNAI | 
    2900:
    EGKSNTVASL | HTEKNTLELS | NGVIVKINNQ | LTLDSNTKYF | HKLNIPKLDF | 
    2950:
    SSQADLRNEI | KTLLKAGHIA | WTSSGKGSWK | WACPRFSDEG | THESQISFTI | 
    3000:
    EGPLTSFGLS | NKINSKHLRV | NQNLVYESGS | LNFSKLEIQS | QVDSQHVGHS | 
    3050:
    VLTAKGMALF | GEGKAEFTGR | HDAHLNGKVI | GTLKNSLFFS | AQPFEITAST | 
    3100:
    NNEGNLKVRF | PLRLTGKIDF | LNNYALFLSP | SAQQASWQVS | ARFNQYKYNQ | 
    3150:
    NFSAGNNENI | MEAHVGINGE | ANLDFLNIPL | TIPEMRLPYT | IITTPPLKDF | 
    3200:
    SLWEKTGLKE | FLKTTKQSFD | LSVKAQYKKN | KHRHSITNPL | AVLCEFISQS | 
    3250:
    IKSFDRHFEK | NRNNALDFVT | KSYNETKIKF | DKYKAEKSHD | ELPRTFQIPG | 
    3300:
    YTVPVVNVEV | SPFTIEMSAF | GYVFPKAVSM | PSFSILGSDV | RVPSYTLILP | 
    3350:
    SLELPVLHVP | RNLKLSLPDF | KELCTISHIF | IPAMGNITYD | FSFKSSVITL | 
    3400:
    NTNAELFNQS | DIVAHLLSSS | SSVIDALQYK | LEGTTRLTRK | RGLKLATALS | 
    3450:
    LSNKFVEGSH | NSTVSLTTKN | MEVSVATTTK | AQIPILRMNF | KQELNGNTKS | 
    3500:
    KPTVSSSMEF | KYDFNSSMLY | STAKGAVDHK | LSLESLTSYF | SIESSTKGDV | 
    3550:
    KGSVLSREYS | GTIASEANTY | LNSKSTRSSV | KLQGTSKIDD | IWNLEVKENF | 
    3600:
    AGEATLQRIY | SLWEHSTKNH | LQLEGLFFTN | GEHTSKATLE | LSPWQMSALV | 
    3650:
    QVHASQPSSF | HDFPDLGQEV | ALNANTKNQK | IRWKNEVRIH | SGSFQSQVEL | 
    3700:
    SNDQEKAHLD | IAGSLEGHLR | FLKNIILPVY | DKSLWDFLKL | DVTTSIGRRQ | 
    3750:
    HLRVSTAFVY | TKNPNGYSFS | IPVKVLADKF | IIPGLKLNDL | NSVLVMPTFH | 
    3800:
    VPFTDLQVPS | CKLDFREIQI | YKKLRTSSFA | LNLPTLPEVK | FPEVDVLTKY | 
    3850:
    SQPEDSLIPF | FEITVPESQL | TVSQFTLPKS | VSDGIAALDL | NAVANKIADF | 
    3900:
    ELPTIIVPEQ | TIEIPSIKFS | VPAGIVIPSF | QALTARFEVD | SPVYNATWSA | 
    3950:
    SLKNKADYVE | TVLDSTCSST | VQFLEYELNV | LGTHKIEDGT | LASKTKGTFA | 
    4000:
    HRDFSAEYEE | DGKYEGLQEW | EGKAHLNIKS | PAFTDLHLRY | QKDKKGISTS | 
    4050:
    AASPAVGTVG | MDMDEDDDFS | KWNFYYSPQS | SPDKKLTIFK | TELRVRESDE | 
    4100:
    ETQIKVNWEE | EAASGLLTSL | KDNVPKATGV | LYDYVNKYHW | EHTGLTLREV | 
    4150:
    SSKLRRNLQN | NAEWVYQGAI | RQIDDIDVRF | QKAASGTTGT | YQEWKDKAQN | 
    4200:
    LYQELLTQEG | QASFQGLKDN | VFDGLVRVTQ | EFHMKVKHLI | DSLIDFLNFP | 
    4250:
    RFQFPGKPGI | YTREELCTMF | IREVGTVLSQ | VYSKVHNGSE | ILFSYFQDLV | 
    4300:
    ITLPFELRKH | KLIDVISMYR | ELLKDLSKEA | QEVFKAIQSL | KTTEVLRNLQ | 
    4350:
    DLLQFIFQLI | EDNIKQLKEM | KFTYLINYIQ | DEINTIFSDY | IPYVFKLLKE | 
    4400:
    NLCLNLHKFN | EFIQNELQEA | SQELQQIHQY | IMALREEYFD | PSIVGWTVKY | 
    4450:
    YELEEKIVSL | IKNLLVALKD | FHSEYIVSAS | NFTSQLSSQV | EQFLHRNIQE | 
    4500:
    YLSILTDPDG | KGKEKIAELS | ATAQEIIKSQ | AIATKKIISD | YHQQFRYKLQ | 
    4550:
    DFSDQLSDYY | EKFIAESKRL | IDLSIQNYHT | FLIYITELLK | KLQSTTVMNP | 
    4563:
    YMKLAPGELT | IIL
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    MIM:
    KEGG:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Apo B-100
    Cat.:
    E2003h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Apo B-100
    MSDS:
    Please sign in first.
    ELISA Kit for Human Apo B-100
    Cat.:
    E2003r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Apo B-100
    MSDS:
    Please sign in first.
    ELISA Kit for Human Apo B-100
    Cat.:
    E2003m
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human Apo B-100
    Cat.:
    U2003r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Apo B-100
    MSDS:
    Please sign in first.
    CLIA Kit for Human Apo B-100
    MSDS:
    Please sign in first.
    CLIA Kit for Human Apo B-100
    Cat.:
    U2003h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Apo B-100
    Cat.:
    U2003m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Apo B-100
    Cat.:
    P2003Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Apo B-100
    Cat.:
    P2003Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Apo B-100
    Polyclonal Antibody for Human Apo B-100
    Cat.:
    P2003Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Apo B-100
    Monoclonal Antibody for Human Apo B-100
    Monoclonal Antibody for Human Apo B-100
    Monoclonal Antibody for Human Apo B-100
    Monoclonal Antibody for Human Apo B-100
    Monoclonal Antibody for Human Apo B-100
    Protein for Human Apo B-100
    Protein for Human Apo B-100
    Protein for Human Apo B-100
    Protein for Human Apo B-100
    Protein for Human Apo B-100

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS ASN-273; GLU-1218; CYS-1422; RP VAL-2092; VAL-2313; THR-2365; GLN-2680; HIS-3319; LYS-3427; GLU-3432; THR-3732; LEU-3949; PHE-3964; LYS-4181 AND ASN-4338
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS CYS-1422; VAL-2313; HIS-3319; LYS-3427; GLU-3432 AND ASN-4338
    3. 3.
      "The complete cDNA and amino acid sequence of human apolipoprotein B-100."
      Chen S.-H. , Yang C.-Y. , Chen P.-F. , Setzer D. , Tanimura M. , Li W.-H. , Gotto A.M. Jr. , Chan L.
      J. Biol. Chem.261:12918-12921(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS ILE-98; VAL-618; CYS-1422; VAL-2313; HIS-3319; LYS-3427; GLU-3432 AND ASN-4338
    4. 4.
      "Human liver apolipoprotein B-100 cDNA: complete nucleic acid and derived amino acid sequence."
      Law S.W. , Grant S.M. , Higuchi K. , Hospattankar A.V. , Lackner K.J. , Lee N. , Brewer H.B. Jr.
      Proc. Natl. Acad. Sci. U.S.A.83:8142-8146(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS CYS-1422; ASN-2037; VAL-2313; HIS-3319; LYS-3427; GLU-3432; LEU-3949; LYS-4181 AND ASN-4338
    5. 5.
      "The complete sequence and structural analysis of human apolipoprotein B-100: relationship between apoB-100 and apoB-48 forms."
      Cladaras C. , Hadzopoulou-Cladaras M. , Nolte R.T. , Atkinson D. , Zannis V.I.
      EMBO J.5:3495-3507(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-40;VARIANTS VAL-618; CYS-1422; VAL-2313; HIS-3319; LYS-3427; GLU-3432; THR-3732; LEU-3949; PHE-3964; LYS-4181 AND ASN-4338
    6. 6.
      SeattleSNPs variation discovery resource
      Submitted (2003-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS CYS-1422; VAL-2313 AND ASN-4338
    7. 7.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "Analysis of cDNA clones encoding the entire B-26 region of human apolipoprotein B."
      Protter A.A. , Hardman D.A. , Sato K.Y. , Schilling J.W. , Yamanaka M. , Hort Y.J. , Hjerrild K.A. , Chen G.C. , Kane J.P.
      Proc. Natl. Acad. Sci. U.S.A.83:5678-5682(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-1670;VARIANTS ILE-98; CYS-1422 AND ASP-1670
    9. 9.
      "Isolation of a cDNA clone encoding the amino-terminal region of human apolipoprotein B."
      Protter A.A. , Hardman D.A. , Schilling J.W. , Miller J. , Appleby V. , Chen G.C. , Kirsher S.W. , McEnroe G. , Kane J.P.
      Proc. Natl. Acad. Sci. U.S.A.83:1467-1471(1986) [PubMed] [Europe PMC] [Abstract]
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    10. 10.
      "Isolation and characterization of sulfhydryl and disulfide peptides of human apolipoprotein B-100."
      Yang C.Y. , Kim T.W. , Weng S.A. , Lee B.R. , Yang M.L. , Gotto A.M. Jr.
      Proc. Natl. Acad. Sci. U.S.A.87:5523-5527(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;DISULFIDE BONDS;VARIANT ILE-98
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      Law S.W. , Lackner K.J. , Hospattankar A.V. , Anchors J.M. , Sakaguchi A.Y. , Naylor S.L. , Brewer H.B. Jr.
      Proc. Natl. Acad. Sci. U.S.A.82:8340-8344(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 485-1044
      tissue: Liver.
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 709-906
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      LeBoeuf R.C. , Miller C. , Shively J.E. , Schumaker V.N. , Balla M.A. , Lusis A.J.
      FEBS Lett.170:105-108(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 873-896 AND 3113-3137
    14. 14.
      "Hypobetalipoproteinemia due to an apolipoprotein B gene exon 21 deletion derived by Alu-Alu recombination."
      Huang L.S. , Ripps M.E. , Korman S.H. , Deckelbaum R.J. , Breslow J.L.
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      Carlsson P. , Darnfors C. , Olofsson S.O. , Bjursell G.
      Gene49:29-51(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1282-4503;VARIANTS CYS-1422; VAL-2313; HIS-3319; LYS-3427; GLU-3432; THR-3732 AND ASN-4338
    16. 16.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1671-2398;VARIANT VAL-2313
    17. 17.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1937-2018 AND 3811-4334
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      "A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine."
      Powell L.M. , Wallis S.C. , Pease R.J. , Edwards Y.H. , Knott T.J. , Scott J.
      Cell50:831-840(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2115-2179
      tissue: Small intestine.
    19. 19.
      "Human apolipoprotein B (apoB) mRNA: identification of two distinct apoB mRNAs, an mRNA with the apoB-100 sequence and an apoB mRNA containing a premature in-frame translational stop codon, in both liver and intestine."
      Higuchi K. , Hospattankar A.V. , Law S.W. , Meglin N. , Cortright J. , Brewer H.B. Jr.
      Proc. Natl. Acad. Sci. U.S.A.85:1772-1776(1988) [PubMed] [Europe PMC] [Abstract]
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      "Carboxyl terminal analysis of human B-48 protein confirms the novel mechanism proposed for chain termination."
      Hardman D.A. , Protter A.A. , Schilling J.W. , Kane J.P.
      Biochem. Biophys. Res. Commun.149:1214-1219(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2129-2235
    21. 21.
      "Identification of a novel in-frame translational stop codon in human intestine apoB mRNA."
      Hospattankar A.V. , Higuchi K. , Law S.W. , Meglin N. , Brewer H.B. Jr.
      Biochem. Biophys. Res. Commun.148:279-285(1987) [PubMed] [Europe PMC] [Abstract]
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    22. 22.
      "Human apolipoprotein B: identification of cDNA clones and characterization of mRNA."
      Mehrabian M. , Schumaker V.N. , Fareed G.C. , West R. , Johnson D.F. , Kirchgessner T.G. , Lin H.-C. , Wang X. , Ma Y. , Mendiaz E. , Lusis A.J.
      Nucleic Acids Res.13:6937-6953(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 3056-3159
    23. 23.
      "Human apolipoprotein B: structure of carboxyl-terminal domains, sites of gene expression, and chromosomal localization."
      Knott T.J. , Rall S.C. Jr. , Innerarity T.L. , Jacobson S.F. , Urdea M.S. , Levy-Wilson B. , Powell L.M. , Pease R.J. , Eddy R. , Nakai H. , Byers M. , Priestley L.M. , Robertson E. , Rall L.B. , Betsholtz C. , Shows T.B. , Mahley R.W. , Scott J.
      Science230:37-43(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 3109-4563;VARIANTS HIS-3319; LYS-3427; GLU-3432; THR-3732; LEU-3949; PHE-3964; LYS-4181 AND ASN-4338
    24. 24.
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      Wei C.F. , Chen S.H. , Yang C.Y. , Marcel Y.L. , Milne R.W. , Li W.H. , Sparrow J.T. , Gotto A.M. Jr. , Chan L.
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      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 3728-4563;VARIANT ASN-4338
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      "Molecular cloning of human LDL apolipoprotein B cDNA. Evidence for more than one gene per haploid genome."
      Shoulders C.C. , Myant N.B. , Sidoli A. , Rodriguez J.C. , Cortese C. , Baralle F.E. , Cortese R.
      Atherosclerosis58:277-289(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 3846-4298;VARIANTS LEU-3949; PHE-3964 AND LYS-4181
      tissue: Liver.
    26. 26.
      "Isolation, expression and characterization of a human apolipoprotein B 100-specific cDNA clone."
      Pfitzner R. , Wagener R. , Stoffel W.
      Biol. Chem. Hoppe-Seyler367:1077-1083(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4217-4563
    27. 27.
      "Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon."
      Chen S.-H. , Habib G. , Yang C.-H. , Gu Z.-W. , Lee B.R. , Weng S.-H. , Silberman S.R. , Cai S.-J. , Deslypere J.P. , Rosseneu M. , Gotto A.M. Jr. , Li W.-H. , Chan L.
      Science238:363-366(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;IDENTIFICATION OF APO-B48
    28. 28.
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    29. 29.
      "Sequence, structure, receptor-binding domains and internal repeats of human apolipoprotein B-100."
      Yang C.-Y. , Chen S.-H. , Gianturco S.H. , Bradley W.A. , Sparrow J.T. , Tanimura M. , Li W.-H. , Sparrow D.A. , Deloof H. , Rosseneu M. , Lee F.-S. , Gu Z.-W. , Gotto A.M. Jr. , Chan L.
      Nature323:738-742(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DOMAINS
    30. 30.
      "Apolipoprotein B is a calcium binding protein."
      Dashti N. , Lee D.M. , Mok T.
      Biochem. Biophys. Res. Commun.137:493-499(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CALCIUM-BINDING
    31. 31.
      "Palmitoylation of apolipoprotein B is required for proper intracellular sorting and transport of cholesteroyl esters and triglycerides."
      Zhao Y. , McCabe J.B. , Vance J. , Berthiaume L.G.
      Mol. Biol. Cell11:721-734(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION AT CYS-1112
    32. 32.
      "Screening for N-glycosylated proteins by liquid chromatography mass spectrometry."
      Bunkenborg J. , Pilch B.J. , Podtelejnikov A.V. , Wisniewski J.R.
      Proteomics4:454-465(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-3358
      tissue: Plasma.
    33. 33.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1523; ASN-2982; ASN-3465 AND ASN-3895
      tissue: Plasma.
    34. 34.
      "Transcriptomic and proteomic analyses of rhabdomyosarcoma cells reveal differential cellular gene expression in response to enterovirus 71 infection."
      Leong W.F. , Chow V.T.
      Cell. Microbiol.8:565-580(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;IDENTIFICATION BY MASS SPECTROMETRY
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      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-185; ASN-1523; ASN-2239; ASN-2779; ASN-2982; ASN-3101; ASN-3224; ASN-3411; ASN-3465 AND ASN-3895
      tissue: Liver.
    36. 36.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-2004;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    37. 37.
      "Biological, clinical and population relevance of 95 loci for blood lipids."
      Teslovich T.M. , Musunuru K. , Smith A.V. , Edmondson A.C. , Stylianou I.M. , Koseki M. , Pirruccello J.P. , Ripatti S. , Chasman D.I. , Willer C.J. , Johansen C.T. , Fouchier S.W. , Isaacs A. , Peloso G.M. , Barbalic M. , Ricketts S.L. , Bis J.C. , Aulchenko Y.S. , more...
      Nature466:707-713(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN LDLCQ4;VARIANT ILE-98
    38. 38.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    39. 39.
      "A novel mutation of apolipoprotein B in a French Canadian family with homozygous hypobetalipoproteinemia."
      Gangloff A. , Bergeron J. , Couture P. , Martins R. , Hegele R.A. , Gagne C.
      J. Clin. Lipidol.5:414-417(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN FHBL1
    40. 40.
      "Proprotein convertase subtilisin/kexin type 9 interacts with apolipoprotein B and prevents its intracellular degradation, irrespective of the low-density lipoprotein receptor."
      Sun H. , Samarghandi A. , Zhang N. , Yao Z. , Xiong M. , Teng B.B.
      Arterioscler. Thromb. Vasc. Biol.32:1585-1595(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH PCSK9
    41. 41.
      "Detection by denaturing gradient gel electrophoresis of a new polymorphism in the apolipoprotein B gene."
      Navajas M. , Laurent A.-M. , Moreel J.-F. , Ragab A. , Cambou J.-P. , Cunny G. , Cambien F. , Roizes G.
      Hum. Genet.86:91-93(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ASN-4338
    42. 42.
      "Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100."
      Soria L.F. , Ludwig E.H. , Clarke H.R.G. , Vega G.L. , Grundy S.M. , McCarthy B.J.
      Proc. Natl. Acad. Sci. U.S.A.86:587-591(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT FDB GLN-3527
    43. 43.
      "Sequence polymorphism in the human apoB gene at position 8344."
      Huang L.-S. , Gavish D. , Breslow J.L.
      Nucleic Acids Res.18:5922-5922(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LEU-2739
    44. 44.
      "Familial ligand-defective apolipoprotein B. Identification of a new mutation that decreases LDL receptor binding affinity."
      Pullinger C.R. , Hennessy L.K. , Chatterton J.E. , Liu W. , Love J.A. , Mendel C.M. , Frost P.H. , Malloy M.J. , Schumaker V.N. , Kane J.P.
      J. Clin. Invest.95:1225-1234(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT FDB CYS-3558
    45. 45.
      "Detection of new variants in the apolipoprotein B (Apo B) gene by PCR-SSCP."
      Poirier O. , Ricard S. , Behague I. , Souriau C. , Evans A.E. , Arveiler D. , Marques-Vidal P. , Luc G. , Roizes G. , Cambien F.
      Hum. Mutat.8:282-285(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LEU-1437; SER-1914; LYS-2566; THR-3121; ALA-3945; MET-4128 AND THR-4481
    46. 46.
      "Familial ligand-defective apolipoprotein B-100: simultaneous detection of the Arg3500-->Gln and Arg3531-->Cys mutations in a French population."
      Rabes J.P. , Varret M. , Saint-Jore B. , Erlich D. , Jondeau G. , Krempf M. , Giraudet P. , Junien C. , Boileau C.
      Hum. Mutat.10:160-163(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS FDB GLN-3527 AND CYS-3558
    47. 47.
      "Screening for mutations of the apolipoprotein B gene causing hypocholesterolemia."
      Leren T.P. , Bakken K.S. , Hoel V. , Hjermann I. , Berg K.
      Hum. Genet.102:44-49(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS SER-1914; ARG-1923; LEU-2739; HIS-3319; LYS-3427; GLU-3432 AND ILE-3921
    48. 48.
      "A novel nontruncating APOB gene mutation, R463W, causes familial hypobetalipoproteinemia."
      Burnett J.R. , Shan J. , Miskie B.A. , Whitfield A.J. , Yuan J. , Tran K. , McKnight C.J. , Hegele R.A. , Yao Z.
      J. Biol. Chem.278:13442-13452(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT FHBL1 TRP-490;VARIANT ILE-98;CHARACTERIZATION OF VARIANT TRP-490;MUTAGENESIS OF ASP-483 AND ARG-490
    49. 49.
      "Hypobetalipoproteinemia with an apparently recessive inheritance due to a 'de novo' mutation of apolipoprotein B."
      Lancellotti S. , Di Leo E. , Penacchioni J.Y. , Balli F. , Viola L. , Bertolini S. , Calandra S. , Tarugi P.
      Biochim. Biophys. Acta1688:61-67(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HIS-1128
    50. 50.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] CYS-2564
    51. 51.
      "Molecular basis of autosomal dominant hypercholesterolemia: assessment in a large cohort of hypercholesterolemic children."
      van der Graaf A. , Avis H.J. , Kusters D.M. , Vissers M.N. , Hutten B.A. , Defesche J.C. , Huijgen R. , Fouchier S.W. , Wijburg F.A. , Kastelein J.J. , Wiegman A.
      Circulation123:1167-1173(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT FDB GLN-3527
    52. 52.
      "Quantitative detection of single amino acid polymorphisms by targeted proteomics."
      Su Z.D. , Sun L. , Yu D.X. , Li R.X. , Li H.X. , Yu Z.J. , Sheng Q.H. , Lin X. , Zeng R. , Wu J.R.
      J. Mol. Cell Biol.3:309-315(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GLU-1218; ASP-1670; ASN-2037; CYS-2564 AND LYS-2566;IDENTIFICATION BY MASS SPECTROMETRY
    53. 53.
      "Genetic variation in APOB, PCSK9, and ANGPTL3 in carriers of pathogenic autosomal dominant hypercholesterolemic mutations with unexpected low LDL-Cl Levels."
      Huijgen R. , Sjouke B. , Vis K. , de Randamie J.S. , Defesche J.C. , Kastelein J.J. , Hovingh G.K. , Fouchier S.W.
      Hum. Mutat.33:448-455(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS 12-LEU--LEU-14 DEL; ILE-98; VAL-618; ILE-730; THR-1613; ARG-1923; LYS-2566; LEU-2739; GLN-3638; LEU-3835; LYS-4181; THR-4270; VAL-4314; ASN-4338; THR-4481 AND VAL-4482
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