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Index > Protein center > Atf2(Gene name) > Mouse
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  • Atf2 (Gene name),
  • Cyclic AMP-dependent transcription factor ATF-2 (Protein name ),  ATF2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Atf2;
    Protein name:
    Cyclic AMP-dependent transcription factor ATF-2(cAMP-dependent transcription factor ATF-2);
    Alternative:
    cAMP response element-binding protein CRE-BP1;Activating transcription factor 2;MXBP protein;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Binds DNA as a dimer and can form a homodimer in the absence of DNA. Can form a heterodimer with JUN. Interacts with SMAD3 and SMAD4. Binds through its N-terminal region to UTF1 which acts as a coactivator of ATF2 transcriptional activity.
    Function:
    Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    487
    Sequence:
    50:
    MSDDKPFLCT | APGCGQRFTN | EDHLAVHKHK | HEMTLKFGPA | RNDSVIVADQ | 
    100:
    TPTPTRFLKN | CEEVGLFNEL | ASPFENEFKK | ASEDDIKKMP | LDLSPLATPI | 
    150:
    IRSKIEEPSV | VETTHQDSPL | PHPESTTSDE | KEVPLAQTAQ | PTSAIVRPAS | 
    200:
    LQVPNVLLTS | SDSSVIIQQA | VPSPTSSTVI | TQAPSSNRPI | VPVPGPFPLL | 
    250:
    LHLPNGQTMP | VAIPASITSS | NVHVPAAVPL | VRPVTMVPSV | PGIPGPSSPQ | 
    300:
    PVQSEAKMRL | KAALTQQHPP | VTNGDTVKGH | GSGLVRTQSE | ESRPQSLQQP | 
    350:
    ATSTTETPAS | PAHTTPQTQN | TSGRRRRAAN | EDPDEKRRKF | LERNRAAASR | 
    400:
    CRQKRKVWVQ | SLEKKAEDLS | SLNGQLQSEV | TLLRNEVAQL | KQLLLAHKDC | 
    450:
    PVTAMQKKSG | YHTADKDDSS | EDLSVPSSPH | TEAIQHSSVS | TSNGVSSTSK | 
    487:
    AEAVATSVLT | QMADQSTEPA | LSQIVMAPPS | QAQPSGS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    String:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse cAMP-dependent transcription factor ATF-2
    Cat.:
    E8848r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse cAMP-dependent transcription factor ATF-2
    MSDS:
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    ELISA Kit for Mouse cAMP-dependent transcription factor ATF-2
    Cat.:
    E8848h
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse cAMP-dependent transcription factor ATF-2
    Cat.:
    E8848m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse cAMP-dependent transcription factor ATF-2
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse cAMP-dependent transcription factor ATF-2
    Cat.:
    U8848r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse cAMP-dependent transcription factor ATF-2
    Cat.:
    U8848m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse cAMP-dependent transcription factor ATF-2
    Cat.:
    U8848h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse cAMP-dependent transcription factor ATF-2
    Cat.:
    P8848Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse cAMP-dependent transcription factor ATF-2
    Polyclonal Antibody for Mouse cAMP-dependent transcription factor ATF-2
    Polyclonal Antibody for Mouse cAMP-dependent transcription factor ATF-2
    Cat.:
    P8848Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse cAMP-dependent transcription factor ATF-2
    Monoclonal Antibody for Mouse cAMP-dependent transcription factor ATF-2
    Monoclonal Antibody for Mouse cAMP-dependent transcription factor ATF-2
    Monoclonal Antibody for Mouse cAMP-dependent transcription factor ATF-2
    Protein for Mouse cAMP-dependent transcription factor ATF-2
    Protein for Mouse cAMP-dependent transcription factor ATF-2
    Protein for Mouse cAMP-dependent transcription factor ATF-2
    Protein for Mouse cAMP-dependent transcription factor ATF-2

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    References
    1. 1.
      "High-throughput sequence identification of gene coding variants within alcohol-related QTLs."
      Ehringer M.A. , Thompson J. , Conroy O. , Xu Y. , Yang F. , Canniff J. , Beeson M. , Gordon L. , Bennett B. , Johnson T.E. , Sikela J.M.
      Mamm. Genome12:657-663(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      strain: ILS.
      strain: ISS.
    2. 2.
      "Functionally distinct isoforms of the CRE-BP DNA-binding protein mediate activity of a T-cell-specific enhancer."
      Georgopoulos K. , Morgan B.A. , Moore D.D.
      Mol. Cell. Biol.12:747-757(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 9-487;ALTERNATIVE SPLICING
    3. 3.
      "mXBP/CRE-BP2 and c-Jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element."
      Ivashkiv L.B. , Liou H.-C. , Kara C.J. , Lamph W.W. , Verma I.M. , Glimcher L.H.
      Mol. Cell. Biol.10:1609-1621(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 77-487
    4. 4.
      "UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells."
      Okuda A. , Fukushima A. , Nishimoto M. , Orimo A. , Yamagishi T. , Nabeshima Y. , Kuro-o M. , Nabeshima Y. , Boon K. , Keaveney M. , Stunnenberg H.G. , Muramatsu M.
      EMBO J.17:2019-2032(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH UTF1
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-51 AND THR-53;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
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