BMP1 ELISA Kit for Human(Homo sapiens) | EIAab.comBMP1 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > BMP1(Gene name) > Human

BMP1 (Gene name),

Bone morphogenetic protein 1 (Protein name ), BMP1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

BMP1(PCOLC);

Protein name:

Bone morphogenetic protein 1(BMP-1);

Alternative:

Procollagen C-proteinase(PCP);Mammalian tolloid protein(mTld);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD).

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

986

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

986:

GDSVLVKFHS | DDTITKKGFH | LRYTSTKFQD | TLHSRK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P13497

MIM:

112264

Pfam:

PF01400

SMR:

P13497

KEGG:

hsa:649

STRING:

9606.ENSP00000305714

UniGene:

Hs.1274

Uniprot:

P13497

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ELISA Kit for Human BMP-1

Cat.:

E1316h

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MSDS:

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Packing:

96T

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ELISA Kit for Human BMP-1

Cat.:

E1316m

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MSDS:

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Packing:

96T

CLIA Kit for Human BMP-1

Cat.:

U1316h

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96T

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CLIA Kit for Human BMP-1

Cat.:

U1316m

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96T

Polyclonal Antibody for Human BMP-1

Cat.:

P1316Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human BMP-1

Cat.:

P1316Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human BMP-1

Protein for Human BMP-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"The C-proteinase that processes procollagens to fibrillar collagens is identical to the protein previously identified as bone morphogenic protein-1."
Li S.W. , Sieron A.L. , Fertala A. , Hojima Y. , Arnold W.V. , Prockop D.J.
Proc. Natl. Acad. Sci. U.S.A.93:5127-5130(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM BMP1-3)
tissue: Skin.
2.

"Novel regulators of bone formation: molecular clones and activities."
Wozney J.M. , Rosen V. , Celeste A.J. , Mitsock L.M. , Whitters M.J. , Kriz R.W. , Hewick R.M. , Wang E.A.
Science242:1528-1534(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM BMP1-1)
3.

"Three alternatively spliced variants of the gene coding for the human bone morphogenetic protein-1."
Janitz M. , Heiser V. , Boettcher U. , Landt O. , Lauster R.
J. Mol. Med.76:141-146(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS BMP1-4; BMP1-5 AND BMP1-6)
tissue: Placenta.
4.

"Bone morphogenetic protein-1 and a mammalian tolloid homologue (mTld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues."
Takahara K. , Lyons G.E. , Greenspan D.S.
J. Biol. Chem.269:32572-32578(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS BMP1-3 AND BMP1-7)
tissue: Placenta.
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM BMP1-5)
tissue: Placenta.
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM BMP1-3)
tissue: Brain.
8.

"Identification of amino acid residues in bone morphogenetic protein-1 important for procollagen C-proteinase activity."
Garrigue-Antar L. , Barker C. , Kadler K.E.
J. Biol. Chem.276:26237-26242(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BOND AT 183-CYS--CYS-186
9.

"Paired basic/Furin-like proprotein convertase cleavage of Pro-BMP-1 in the trans-Golgi network."
Leighton M. , Kadler K.E.
J. Biol. Chem.278:18478-18484(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;PROTEOLYTIC CLEAVAGE;MUTAGENESIS OF 119-ARG--ARG-120
10.

"An unappreciated role for RNA surveillance."
Hillman R.T. , Green R.E. , Brenner S.E.
Genome Biol.5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SPLICE ISOFORM(S) THAT ARE POTENTIAL NMD TARGET(S)
11.

"Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases."
Mac Sweeney A. , Gil-Parrado S. , Vinzenz D. , Bernardi A. , Hein A. , Bodendorf U. , Erbel P. , Logel C. , Gerhartz B.
J. Mol. Biol.384:228-239(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.25 ANGSTROMS) OF 121-321;ZINC-BINDING SITES;COFACTOR;ACTIVE SITE;DISULFIDE BONDS
12.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] HIS-45
13.

"Attenuated BMP1 function compromises osteogenesis, leading to bone fragility in humans and zebrafish."
Asharani P.V. , Keupp K. , Semler O. , Wang W. , Li Y. , Thiele H. , Yigit G. , Pohl E. , Becker J. , Frommolt P. , Sonntag C. , Altmuller J. , Zimmermann K. , Greenspan D.S. , Akarsu N.A. , Netzer C. , Schonau E. , Wirth R. , more...
Am. J. Hum. Genet.90:661-674(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT OI13 ARG-12;CHARACTERIZATION OF VARIANT OI13 ARG-12
14.

"Identification of a mutation causing deficient BMP1/mTLD proteolytic activity in autosomal recessive osteogenesis imperfecta."
Martinez-Glez V. , Valencia M. , Caparros-Martin J.A. , Aglan M. , Temtamy S. , Tenorio J. , Pulido V. , Lindert U. , Rohrbach M. , Eyre D. , Giunta C. , Lapunzina P. , Ruiz-Perez V.L.
Hum. Mutat.33:343-350(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT OI13 LEU-249;CHARACTERIZATION OF VARIANT OI13 LEU-249

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