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Index > Protein center > CCL20(Gene name) > Human
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  • CCL20 (Gene name),
  • C-C motif chemokine 20 (Protein name ),  CCL20_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CCL20(LARC;MIP3A;SCYA20);
    Protein name:
    C-C motif chemokine 20;
    Alternative:
    CC chemokine LARC;Beta-chemokine exodus-1;Macrophage inflammatory protein 3 alpha(MIP-3-alpha);Liver and activation-regulated chemokine;Small-inducible cytokine A20;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds to and activate CCR6.
    Function:
    Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    96
    Sequence:
    50:
    MCCTKSLLLA | ALMSVLLLHL | CGESEAASNF | DCCLGYTDRI | LHPKFIVGFT | 
    96:
    RQLANEGCDI | NAIIFHTKKK | LSVCANPKQT | WVKYIVRLLS | KKVKNM
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    SMR:
    Pfam:
    KEGG:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human C-C motif chemokine 20
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    E0095h
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    ELISA Kit for Human C-C motif chemokine 20
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    E0095r
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    ELISA Kit for Human C-C motif chemokine 20
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    ELISA Kit for Human C-C motif chemokine 20
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    E0095b
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    96T
    CLIA Kit for Human C-C motif chemokine 20
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    U0095b
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    96T
    CLIA Kit for Human C-C motif chemokine 20
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    U0095r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human C-C motif chemokine 20
    Cat.:
    U0095h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human C-C motif chemokine 20
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    U0095m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human C-C motif chemokine 20
    Cat.:
    P0095Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human C-C motif chemokine 20
    Cat.:
    P0095Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human C-C motif chemokine 20
    Polyclonal Antibody for Human C-C motif chemokine 20
    Cat.:
    P0095Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human C-C motif chemokine 20
    Monoclonal Antibody for Human C-C motif chemokine 20
    Monoclonal Antibody for Human C-C motif chemokine 20
    Monoclonal Antibody for Human C-C motif chemokine 20
    Protein for Human C-C motif chemokine 20
    Protein for Human C-C motif chemokine 20
    Protein for Human C-C motif chemokine 20
    Protein for Human C-C motif chemokine 20

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    References
    1. 1.
      "Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3alpha and MIP-3beta."
      Rossi D.L. , Vicari A.P. , Franz-Bacon K. , McClanahan T.K. , Zlotnik A.
      J. Immunol.158:1033-1036(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Molecular cloning of a novel human CC chemokine liver and activation-regulated chemokine (LARC) expressed in liver. Chemotactic activity for lymphocytes and gene localization on chromosome 2."
      Hieshima K. , Imai T. , Opdenakker G. , van Damme J. , Kusuda J. , Tei H. , Sakaki Y. , Takatsuki K. , Miura R. , Yoshie O. , Nomiyama H.
      J. Biol. Chem.272:5846-5853(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF N-TERMINUS
      tissue: Liver.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Pancreas.
    4. 4.
      "Genomic organization of the CC chemokine mip-3alpha/CCL20/larc/ exodus/SCYA20, showing gene structure, splice variants, and chromosome localization."
      Nelson R.T. , Boyd J. , Gladue R.P. , Paradis T. , Thomas R. , Cunningham A.C. , Lira P. , Brissette W.H. , Hayes L. , Hames L.M. , Neote K.S. , McColl S.R.
      Genomics73:28-37(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
      tissue: Liver.
    5. 5.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Liver.
    7. 7.
      "Regulated production and molecular diversity of human liver and activation-regulated chemokine/macrophage inflammatory protein-3 alpha from normal and transformed cells."
      Schutyser E. , Struyf S. , Menten P. , Lenaerts J.-P. , Conings R. , Put W. , Wuyts A. , Proost P. , Van Damme J.
      J. Immunol.165:4470-4477(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF CCL20(1-67); CCL20(1-64) AND CCL20(2-70);PROTEOLYTIC PROCESSING OF C-TERMINAL
    8. 8.
      "The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins."
      Hoover D.M. , Boulegue C. , Yang D. , Oppenheim J.J. , Tucker K. , Lu W. , Lubkowski J.
      J. Biol. Chem.277:37647-37654(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 27-96;FUNCTION AS AN ANTIMICROBIAL PROTEIN
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