CD36 ELISA Kit for Human(Homo sapiens) | EIAab.comCD36 ELISA Kit for Human(Homo sapiens)

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CD36 (Gene name),

Platelet glycoprotein 4 (Protein name ), CD36_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (2)

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Gene name:

CD36(GP3B;GP4);

Protein name:

Platelet glycoprotein 4;

Alternative:

Glycoprotein IIIb(GPIIIB);Fatty acid translocase(FAT);PAS IV;Leukocyte differentiation antigen CD36;Platelet collagen receptor;PAS-4;Thrombospondin receptor;Platelet glycoprotein IV(GPIV);

CD:

CD36;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with THBS1 and THBS2; the interactions mediate the THBS antiangiogenic activity.

Function:

Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Receptor for thombospondins, THBS1 AND THBS2, mediating their antiangiogenic efects.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

472

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

472:

VGVVMFVAFM | ISYCACRSKT | IK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P16671

MIM:

173510

KEGG:

hsa:948

String:

P16671

UniGene:

Hs.120949

Pfam:

PF01130

Uniprot:

P16671

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ELISA Kit for Human Platelet glycoprotein 4

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E0674h

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96T

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ELISA Kit for Human Platelet glycoprotein 4

Cat.:

E0674m

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96T

ELISA Kit for Human Platelet glycoprotein 4

Cat.:

E0674b

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96T

ELISA Kit for Human Platelet glycoprotein 4

Cat.:

E0674r

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96T

CLIA Kit for Human Platelet glycoprotein 4

Cat.:

U0674m

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Packing:

96T

CLIA Kit for Human Platelet glycoprotein 4

Cat.:

U0674r

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Packing:

96T

CLIA Kit for Human Platelet glycoprotein 4

Cat.:

U0674h

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Manual:

Looking for manual.

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Please sign in first.

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96T

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CLIA Kit for Human Platelet glycoprotein 4

Cat.:

U0674b

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96T

Polyclonal Antibody for Human Platelet glycoprotein 4

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P0674Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human Platelet glycoprotein 4

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P0674Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Platelet glycoprotein 4

Cat.:

P0674Rb-m

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Platelet glycoprotein 4

Protein for Human Platelet glycoprotein 4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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Citations

[1].

"Polymorphism of CD36 gene, carbohydrate metabolism and plasma CD36 concentration in obese children. A preliminary study"

ME Rać, B Krupa, B Garanty-Bogacka, et al.

From:Postepy Hig Med Dosw

[2].

"Is plasma soluble CD36 associated with cardiovascular risk factors in early onset coronary artery disease patients?"

A Krzystolik, V Dziedziejko, K Safranow, et al.

From:Scandinavian Journal of Clinical & Laboratory Investigation

References

1.

"CD36 directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes."
Oquendo P. , Hundt E. , Lawler J. , Seed B.
Cell58:95-101(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Placenta.
2.

Sugimoto Y. , Tsuruo T.
Submitted (1992-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
3.

"Characterization of two alternatively spliced 5'-untranslated exons of the human CD36 gene in different cell types."
Taylor K.T. , Tang Y. , Sobieski D.A. , Lipsky R.H.
Gene133:205-212(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
4.

"Cloning of the cDNA encoding human platelet CD36: comparison to PCR amplified fragments of monocyte, endothelial and HEL cells."
Wyler B. , Daviet L. , Bortkiewicz H. , Bordet J.C. , McGregor J.L.
Thromb. Haemost.70:500-505(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Platelet.
5.

"Structural organization of the gene for human CD36 glycoprotein."
Armesilla A.L. , Vega M.A.
J. Biol. Chem.269:18985-18991(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

SeattleSNPs variation discovery resource
Submitted (2004-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.

"Frequency of CD36 deficiency and identification of novel CD36 gene mutations in the Chinese population."
Wu G.-G. , Curtis B.R. , He B.-R. , Zhou Z.-L. , Zhou Y. , Yang Y.-L. , Li H.-Y. , Shen W.-D. , Liu J.-L. , Zhao T.-M.
Submitted (2010-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3 AND 4);VARIANTS TRP-386 AND ILE-470
8.

"The DNA sequence of human chromosome 7."
Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
9.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Skeletal muscle.
10.

"Isolation and characterization of platelet glycoprotein IV (CD36)."
Tandon N.N. , Lipsky R.H. , Burgess W.H. , Jamieson G.A.
J. Biol. Chem.264:7570-7575(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-37;GLYCOSYLATION
tissue: Platelet.
11.

"Variability of the CD36 gene in West Africa."
Gelhaus A. , Scheding A. , Browne E. , Burchard G.D. , Horstmann R.D.
Hum. Mutat.18:444-450(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 41-203; 274-375 AND 419-472;VARIANTS LYS-123; ALA-174; ASN-232 INS AND THR-271
12.

"Gene encoding the collagen type I and thrombospondin receptor CD36 is located on chromosome 7q11.2."
Fernandez-Ruiz E. , Armesilla A.L. , Sanchez-Madrid F. , Vega M.A.
Genomics17:759-761(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 144-203 (ISOFORM 1/2)
13.

"Vectorial proteomics reveal targeting, phosphorylation and specific fragmentation of polymerase I and transcript release factor (PTRF) at the surface of caveolae in human adipocytes."
Aboulaich N. , Vainonen J.P. , Stralfors P. , Vener A.V.
Biochem. J.383:237-248(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 261-273 AND 369-385
tissue: Adipocyte.
14.

"Thrombospondin sequence motif (CSVTCG) is responsible for CD36 binding."
Asch A.S. , Silbiger S. , Heimer E. , Nachman R.L.
Biochem. Biophys. Res. Commun.182:1208-1217(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH THBS1 AND THBS2
15.

"CD36 is palmitoylated on both N- and C-terminal cytoplasmic tails."
Tao N. , Wagner S.J. , Lublin D.M.
J. Biol. Chem.271:22315-22320(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION AT CYS-3; CYS-7; CYS-464 AND CYS-466
16.

"Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach."
Lewandrowski U. , Moebius J. , Walter U. , Sickmann A.
Mol. Cell. Proteomics5:226-233(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-417
tissue: Platelet.
17.

"Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry."
Picariello G. , Ferranti P. , Mamone G. , Roepstorff P. , Addeo F.
Proteomics8:3833-3847(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-321
tissue: Milk.
18.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-205 AND ASN-417
tissue: Liver.
19.

"CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer."
Stewart C.R. , Stuart L.M. , Wilkinson K. , van Gils J.M. , Deng J. , Halle A. , Rayner K.J. , Boyer L. , Zhong R. , Frazier W.A. , Lacy-Hulbert A. , El Khoury J. , Golenbock D.T. , Moore K.J.
Nat. Immunol.11:155-161(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH LYN; PTK2; PXN; TLR4 AND TLR6;SUBCELLULAR LOCATION;MUTAGENESIS OF 462-SER--LYS-473; TYR-463 AND CYS-464
20.

"Molecular basis of CD36 deficiency. Evidence that a 478C-->T substitution (proline90-->serine) in CD36 cDNA accounts for CD36 deficiency."
Kashiwagi H. , Tomiyama Y. , Honda S. , Kosugi S. , Shiraga M. , Nagao N. , Sekiguchi S. , Kanayama Y. , Kurata Y. , Matsuzawa Y.
J. Clin. Invest.95:1040-1046(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PG4D SER-90
21.

"Characterization of single-nucleotide polymorphisms in coding regions of human genes."
Cargill M. , Altshuler D. , Ireland J. , Sklar P. , Ardlie K. , Patil N. , Shaw N. , Lane C.R. , Lim E.P. , Kalyanaraman N. , Nemesh J. , Ziaugra L. , Friedland L. , Rolfe A. , Warrington J. , Lipshutz R. , Daley G.Q. , Lander E.S.
Nat. Genet.22:231-238(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PHE-154
22.

Cargill M. , Altshuler D. , Ireland J. , Sklar P. , Ardlie K. , Patil N. , Shaw N. , Lane C.R. , Lim E.P. , Kalyanaraman N. , Nemesh J. , Ziaugra L. , Friedland L. , Rolfe A. , Warrington J. , Lipshutz R. , Daley G.Q. , Lander E.S.
Nat. Genet.23:373-373(1999)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
23.

"Malaria susceptibility and CD36 mutation."
Aitman T.J. , Cooper L.D. , Norsworthy P.J. , Wahid F.N. , Gray J.K. , Curtis B.R. , McKeigue P.M. , Kwiatkowski D. , Greenwood B.M. , Snow R.W. , Hill A.V. , Scott J.
Nature405:1015-1016(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ROLE IN MALARIA INFECTION
24.

"Identification of cryptic splice site, exon skipping, and novel point mutations in type I CD36 deficiency."
Hanawa H. , Watanabe K. , Nakamura T. , Ogawa Y. , Toba K. , Fuse I. , Kodama M. , Kato K. , Fuse K. , Aizawa Y.
J. Med. Genet.39:286-291(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PG4D SER-90; LEU-254 AND LEU-413
25.

"CD36 polymorphism is associated with protection from cerebral malaria."
Omi K. , Ohashi J. , Patarapotikul J. , Hananantachai H. , Naka I. , Looareesuwan S. , Tokunaga K.
Am. J. Hum. Genet.72:364-374(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LEU-127;ROLE IN MALARIA INFECTION
26.

"A common haplotype at the CD36 locus is associated with high free fatty acid levels and increased cardiovascular risk in Caucasians."
Ma X. , Bacci S. , Mlynarski W. , Gottardo L. , Soccio T. , Menzaghi C. , Iori E. , Lager R.A. , Shroff A.R. , Gervino E.V. , Nesto R.W. , Johnstone M.T. , Abumrad N.A. , Avogaro A. , Trischitta V. , Doria A.
Hum. Mol. Genet.13:2197-2205(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN CHDS7
27.

Ma X. , Bacci S. , Mlynarski W. , Gottardo L. , Soccio T. , Menzaghi C. , Iori E. , Lager R.A. , Shroff A.R. , Gervino E.V. , Nesto R.W. , Johnstone M.T. , Abumrad N.A. , Avogaro A. , Trischitta V. , Doria A.
Hum. Mol. Genet.14:3973-3973(2005)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM

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