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Index > Protein center > DICER1(Gene name) > Chicken
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  • DICER1 (Gene name),
  • Endoribonuclease Dicer (Protein name ),  DICER_CHICK from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    DICER1(DICER);
    Protein name:
    Endoribonuclease Dicer;
    Alternative:

    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC.
    Function:
    Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    1921
    Sequence:
    50:
    MKSPALQSLS | MAGLQLMTPA | SSPMGPFFGL | PWQQEAIHDN | IYTPRKYQVE | 
    100:
    LLEAALDHNT | IVCLNTGSGK | TFIAVLLTKE | LSYQIRGDFN | KNGKRTVFLV | 
    150:
    NSANQVAQQV | SAVRTHSDLK | VGEYSSLEVT | ESWTKEKWSQ | EFSKHQVLVM | 
    200:
    TCHVALTVLR | NEYLSLSNIN | LLVFDECHLA | IQDHPYREIM | KICEDYPSCP | 
    250:
    RILGLTASIL | NGKCDPAELE | EKIKKLEKIL | KSNAETATDL | VVLDRYTSQP | 
    300:
    CEIVVDCGPY | TDKSGLYGRL | LRELDEALHF | LNDCNISVHS | KERDSTLISK | 
    350:
    QILSDCRAVL | VVLGPWCADK | VAGMMVRELQ | KYIKHEQEEL | HRKFLLFTDT | 
    400:
    FLRKIHALCE | EHFSPASLDL | KFVTPKVIKL | LEILRKYKPY | ERQQFESVEW | 
    450:
    YNNRNQDNYV | SWSDSEDDDE | DEEIEEKEKP | ETNFPSPFTN | ILCGIIFVER | 
    500:
    RYTAVVLNRL | IKEAGKQDPE | LAYISSNFIT | GHGIGKNQPR | NKQMEVEFRK | 
    550:
    QEEVLRKFRA | HETNLLIATS | IVEEGVDIPK | CNLVVRFDLP | TEYRSYVQSK | 
    600:
    GRARAPISNY | IMLADTDKIK | SFEEDLKTYK | AIEKILRNKC | SKSVDTSETE | 
    650:
    TEPIVDDDDV | FPPYVLRTDE | NSPRVTINTA | IGHINRYCAR | LPSDPFTHLA | 
    700:
    PKCKTRELPD | HTFYSTLYLP | INSPLRASIV | GPPMSCARLA | ERVVALICCE | 
    750:
    KLHKIGELDD | HLMPVGKETV | KYEEELDLHD | EEETSVPGRP | GSTKRRQCYP | 
    800:
    KAIPECLRDS | YPKPDQPCYL | YVIGMVLTTP | LPDELNFRRR | KLYPPEDTTR | 
    850:
    CFGILTAKPI | PQIPHFPVYT | RSGEVTISIE | LKKSGFTLSL | QMLELITRLH | 
    900:
    QYIFSHILRL | EKPALEFKPT | EADSAYCVLP | LNIVDDSSTL | DIDFKFMEDI | 
    950:
    EKSEARTGIP | STQYTKEMPF | IFKLEDYQDA | VIIPRYRNFD | QPHRFYVADV | 
    1000:
    YTDLTPLSKF | PSPEYETFAE | YYKTKYNLDL | TNLNQPLLDV | DHTSSRLNLL | 
    1050:
    TPRHLNQKGK | ALPLSSAEKR | KAKWESLQNK | QILVPELCAI | HPIPASLWRK | 
    1100:
    AVCLPSILYR | LHCLLTAEEL | RAQTATDAGV | GVKSLPADFR | YPNLDFGWKK | 
    1150:
    SIDSKSFISI | PSSSLVENEN | YCKHSTIVVP | ENAAHQGANR | TSSAEKHDQM | 
    1200:
    SVSYRTLLDE | SPSKLQIDVS | AELAAINGVS | YNKNLANGNC | DLVNRDFCQG | 
    1250:
    NQLNYCRQEI | PVQPTTSYPI | QNLYSSENQP | KPSNECTLLS | NKYLDGNANR | 
    1300:
    STSDGCPKMT | VTTSTSTALN | LSKDKVDSEK | NTSSGYSSKT | LGPNPGLILQ | 
    1350:
    ALTLSNASDG | FNLERLEMLG | DSFLKHAITT | YLFCTYPDAH | EGRLSYMRSK | 
    1400:
    KVSNCNLYRL | GKKKGLPSRM | VVSIFDPPVN | WLPPGYIVNQ | DKSNTDKWEK | 
    1450:
    EETTKENLLA | NGKLDYDDDD | EEDEDLMWRL | PKEETDFEDD | FLEYDQEHIK | 
    1500:
    FIDSMLMGSG | AFVKKISLSH | FSTTDSNYEW | KAPKKSSLGN | VPFSSDFDDF | 
    1550:
    DYSSWDAMCY | LDPSKAVEED | DFVVGFWNPS | EENCGVDAGK | QSISYDLHTE | 
    1600:
    QCIADKSIAD | CVEALLGCYL | TSCGERAAQL | FLCSLGLKVL | PVIKKTDWES | 
    1650:
    TLCATGENCN | SEQKNLSPNS | VSACIVNSEP | SLYKDLEYGC | LKIPPRCMFD | 
    1700:
    HPDAEKTLNH | LISGFENFEK | KINYSFKNKA | YLLQAFTHAS | YHYNTITDCY | 
    1750:
    QRLEFLGDAI | LDYLITKHLY | EDPRQHSPGV | LTDLRSALVN | NTIFASLAVK | 
    1800:
    YDYHKYFKAV | SPELFHVIDD | FVQFQMEKNE | MQGMDSELRR | SEEDEEKEED | 
    1850:
    IEVPKAMGDI | FESLAGAIYM | DSGMSLEMVW | QVYYPMMRPL | IEKFSANVPR | 
    1900:
    SPVRELLEME | PETAKFSPAE | RTYDGKVRVT | VEVVGKGKFK | GVGRSYRIAK | 
    1921:
    SAAARRALRS | LKANQPQVPN | S
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken Endoribonuclease Dicer
    Cat.:
    E0156h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Chicken Endoribonuclease Dicer
    Cat.:
    E0156m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Chicken Endoribonuclease Dicer
    Cat.:
    E0156c
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Chicken Endoribonuclease Dicer
    Cat.:
    E0156b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Chicken Endoribonuclease Dicer
    Cat.:
    U0156b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Endoribonuclease Dicer
    Cat.:
    U0156c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Chicken Endoribonuclease Dicer
    Cat.:
    U0156h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Chicken Endoribonuclease Dicer
    Cat.:
    U0156m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Chicken Endoribonuclease Dicer
    Polyclonal Antibody for Chicken Endoribonuclease Dicer
    Cat.:
    P0156Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Chicken Endoribonuclease Dicer
    Polyclonal Antibody for Chicken Endoribonuclease Dicer
    Cat.:
    P0156Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Chicken Endoribonuclease Dicer
    Monoclonal Antibody for Chicken Endoribonuclease Dicer
    Monoclonal Antibody for Chicken Endoribonuclease Dicer
    Monoclonal Antibody for Chicken Endoribonuclease Dicer
    Protein for Chicken Endoribonuclease Dicer
    Protein for Chicken Endoribonuclease Dicer
    Protein for Chicken Endoribonuclease Dicer
    Protein for Chicken Endoribonuclease Dicer

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    Precision
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    References
    1. 1.
      "Dicer is essential for formation of the heterochromatin structure in vertebrate cells."
      Fukagawa T. , Nogami M. , Yoshikawa M. , Ikeno M. , Okazaki T. , Takami Y. , Nakayama T. , Oshimura M.
      Nat. Cell Biol.6:784-791(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
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