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Index > Protein center > ENTPD1(Gene name) > Human
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  • ENTPD1 (Gene name),
  • Ectonucleoside triphosphate diphosphohydrolase 1 (Protein name ),  ENTP1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ENTPD1(CD39);
    Protein name:
    Ectonucleoside triphosphate diphosphohydrolase 1(NTPDase 1);
    Alternative:
    Ecto-apyrase;Ecto-ATP diphosphohydrolase 1(Ecto-ATPDase 1;Ecto-ATPase 1);Lymphoid cell activation antigen;
    CD:
    CD39;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked.
    Function:
    In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation. Hydrolyzes ATP and ADP equally well.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    510
    Sequence:
    50:
    MEDTKESNVK | TFCSKNILAI | LGFSSIIAVI | ALLAVGLTQN | KALPENVKYG | 
    100:
    IVLDAGSSHT | SLYIYKWPAE | KENDTGVVHQ | VEECRVKGPG | ISKFVQKVNE | 
    150:
    IGIYLTDCME | RAREVIPRSQ | HQETPVYLGA | TAGMRLLRME | SEELADRVLD | 
    200:
    VVERSLSNYP | FDFQGARIIT | GQEEGAYGWI | TINYLLGKFS | QKTRWFSIVP | 
    250:
    YETNNQETFG | ALDLGGASTQ | VTFVPQNQTI | ESPDNALQFR | LYGKDYNVYT | 
    300:
    HSFLCYGKDQ | ALWQKLAKDI | QVASNEILRD | PCFHPGYKKV | VNVSDLYKTP | 
    350:
    CTKRFEMTLP | FQQFEIQGIG | NYQQCHQSIL | ELFNTSYCPY | SQCAFNGIFL | 
    400:
    PPLQGDFGAF | SAFYFVMKFL | NLTSEKVSQE | KVTEMMKKFC | AQPWEEIKTS | 
    450:
    YAGVKEKYLS | EYCFSGTYIL | SLLLQGYHFT | ADSWEHIHFI | GKIQGSDAGW | 
    500:
    TLGYMLNLTN | MIPAEQPLST | PLSHSTYVFL | MVLFSLVLFT | VAIIGLLIFH | 
    510:
    KPSYFWKDMV | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    KEGG:
    SMR:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human NTPDase 1
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    E9075m
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    Packing:
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    ELISA Kit for Human NTPDase 1
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    ELISA Kit for Human NTPDase 1
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    ELISA Kit for Human NTPDase 1
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    E9075h
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    ELISA Kit for Human NTPDase 1
    Cat.:
    E9075b
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    Packing:
    96T
    CLIA Kit for Human NTPDase 1
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    U9075p
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    Packing:
    96T
    CLIA Kit for Human NTPDase 1
    Cat.:
    U9075m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NTPDase 1
    Cat.:
    U9075h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human NTPDase 1
    Cat.:
    U9075b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human NTPDase 1
    Cat.:
    U9075r
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human NTPDase 1
    Polyclonal Antibody for Human NTPDase 1
    Cat.:
    P9075Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NTPDase 1
    Polyclonal Antibody for Human NTPDase 1
    Cat.:
    P9075Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human NTPDase 1
    Monoclonal Antibody for Human NTPDase 1
    Monoclonal Antibody for Human NTPDase 1
    Monoclonal Antibody for Human NTPDase 1
    Monoclonal Antibody for Human NTPDase 1
    Monoclonal Antibody for Human NTPDase 1
    Protein for Human NTPDase 1
    Protein for Human NTPDase 1
    Protein for Human NTPDase 1
    Protein for Human NTPDase 1
    Protein for Human NTPDase 1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Loss of ATP diphosphohydrolase activity with endothelial cell activation."
      Robson S.C. , Kaczmarek E. , Siegel J.B. , Candinas D. , Koziak K. , Millan M. , Hancock W.W. , Bach F.H.
      J. Exp. Med.185:153-163(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Umbilical vein.
    3. 3.
      "The cDNA cloning of human placental ecto-ATP diphosphohydrolases I and II."
      Matsumoto M. , Sakurai Y. , Kokubo T. , Yagi H. , Makita K. , Matsui T. , Titani K. , Fujimura Y. , Narita N.
      FEBS Lett.453:335-340(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3)
      tissue: Placenta.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 4; 5 AND 6)
      tissue: Brain.
      tissue: Synovium.
      tissue: Trachea.
      tissue: Uterus.
    5. 5.
      "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
      Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
      tissue: Lung.
    8. 8.
      "Purification and properties of human placental ATP diphosphohydrolase."
      Christoforidis S. , Papamarcaki T. , Galaris D. , Kellner R. , Tsolas O.
      Eur. J. Biochem.234:66-74(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 240-242; 162-166; 185-189; 210-223; 243-249 AND 288-297
      tissue: Placenta.
    9. 9.
      "Placental ecto-ATP diphosphohydrolase: its structural feature distinct from CD39, localization and inhibition on shear-induced platelet aggregation."
      Makita K. , Shimoyama T. , Sakurai Y. , Yagi H. , Matsumoto M. , Narita N. , Sakamoto Y. , Saito S. , Ikeda Y. , Suzuki M. , Titani K. , Fujimura Y.
      Int. J. Hematol.68:297-310(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-30; 49-65; 94-97; 88-93; 193-223; 245-265; 382-385 AND 399-405 (ISOFORM 2)
      tissue: Placenta.
    10. 10.
      "Identification and characterization of CD39/vascular ATP diphosphohydrolase."
      Kaczmarek E. , Koziak K. , Sevigny J. , Siegel J.B. , Anrather J. , Beaudoin A.R. , Bach F.H. , Robson S.C.
      J. Biol. Chem.271:33116-33122(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;COFACTOR
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
    12. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PALMITOYLATION AT CYS-13
    13. 13.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-73 AND ASN-292
      tissue: Liver.
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