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Index > Protein center > FGF20(Gene name) > Human
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  • FGF20 (Gene name),
  • Fibroblast growth factor 20 (Protein name ),  FGF20_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    FGF20;
    Protein name:
    Fibroblast growth factor 20(FGF-20);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer. Interacts with FGFR2 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
    Function:
    Neurotrophic factor that regulates central nervous development and function.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    211
    Sequence:
    50:
    MAPLAEVGGF | LGGLEGLGQQ | VGSHFLLPPA | GERPPLLGER | RSAAERSARG | 
    100:
    GPGAAQLAHL | HGILRRRQLY | CRTGFHLQIL | PDGSVQGTRQ | DHSLFGILEF | 
    150:
    ISVAVGLVSI | RGVDSGLYLG | MNDKGELYGS | EKLTSECIFR | EQFEENWYNT | 
    200:
    YSSNIYKHGD | TGRRYFVALN | KDGTPRDGAR | SKRHQKFTHF | LPRPVDPERV | 
    211:
    PELYKDLLMY | T
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    UniGene:
    SMR:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human FGF-20
    Cat.:
    E9707m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human FGF-20
    Cat.:
    E9707r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human FGF-20
    Cat.:
    E9707h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human FGF-20
    Cat.:
    U9707h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human FGF-20
    Cat.:
    U9707m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human FGF-20
    Cat.:
    U9707r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human FGF-20
    Cat.:
    P9707Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human FGF-20
    Polyclonal Antibody for Human FGF-20
    Cat.:
    P9707Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human FGF-20
    Monoclonal Antibody for Human FGF-20
    Monoclonal Antibody for Human FGF-20
    Protein for Human FGF-20
    Protein for Human FGF-20
    Protein for Human FGF-20

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning and characterization of human FGF-20 on chromosome 8p21.3-p22."
      Kirikoshi H. , Sagara N. , Saitoh T. , Tanaka K. , Sekihara H. , Shiokawa K. , Katoh M.
      Biochem. Biophys. Res. Commun.274:337-343(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "FGF-20, a novel neurotrophic factor, preferentially expressed in the substantia nigra pars compacta of rat brain."
      Ohmachi S. , Watanabe Y. , Mikami T. , Kusu N. , Ibi T. , Akaike A. , Itoh N.
      Biochem. Biophys. Res. Commun.277:355-360(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    3. 3.
      "Identification of a novel human fibroblast growth factor and characterization of its role in oncogenesis."
      Jeffers M. , Shimkets R. , Prayaga S. , Boldog F. , Yang M. , Burgess C. , Fernandes E. , Rittman B. , Shimkets J. , LaRochelle W.J. , Lichenstein H.S.
      Cancer Res.61:3131-3138(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    4. 4.
      NIEHS SNPs program
      Submitted (2004-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ARG-116; ALA-175 AND ASN-206
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    7. 7.
      "Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family."
      Zhang X. , Ibrahimi O.A. , Olsen S.K. , Umemori H. , Mohammadi M. , Ornitz D.M.
      J. Biol. Chem.281:15694-15700(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FGFR2 AND FGFR4;FUNCTION IN STIMULATION OF CELL PROLIFERATION
    8. 8.
      "Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein."
      Wang G. , van der Walt J.M. , Mayhew G. , Li Y.J. , Zuchner S. , Scott W.K. , Martin E.R. , Vance J.M.
      Am. J. Hum. Genet.82:283-289(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POSSIBLE ASSOCIATION WITH PARKINSON DISEASE
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NO EVIDENCE OF ASSOCIATION WITH PARKINSON DISEASE
    10. 10.
      "Fibroblast growth factor signalling: from development to cancer."
      Turner N. , Grose R.
      Nat. Rev. Cancer10:116-129(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    11. 11.
      "FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man."
      Barak H. , Huh S.H. , Chen S. , Jeanpierre C. , Martinovic J. , Parisot M. , Bole-Feysot C. , Nitschke P. , Salomon R. , Antignac C. , Ornitz D.M. , Kopan R.
      Dev. Cell22:1191-1207(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN RHDA2
    12. 12.
      "Homodimerization controls the fibroblast growth factor 9 subfamily's receptor binding and heparan sulfate-dependent diffusion in the extracellular matrix."
      Kalinina J. , Byron S.A. , Makarenkova H.P. , Olsen S.K. , Eliseenkova A.V. , Larochelle W.J. , Dhanabal M. , Blais S. , Ornitz D.M. , Day L.A. , Neubert T.A. , Pollock P.M. , Mohammadi M.
      Mol. Cell. Biol.29:4663-4678(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS);SUBUNIT;HEPARIN-BINDING
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