FOLR2 ELISA Kit for Human(Homo sapiens) | EIAab.comFOLR2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > FOLR2(Gene name) > Human

FOLR2 (Gene name),

Folate receptor beta (Protein name ), FOLR2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

FOLR2;

Protein name:

Folate receptor beta(FR-beta);

Alternative:

Folate receptor, fetal/placental;Folate receptor 2;Placental folate-binding protein(FBP);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate to the interior of cells.

Subcellular Location:

Cell membrane Lipid-anchor GPI-anchor Secreted

Protein Attributes:

Sequence length:

255

Sequence:

50:

100:

150:

200:

250:

255:

LWLLG

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.433159

STRING:

9606.ENSP00000298223

KEGG:

hsa:2350

String:

P14207

MIM:

136425

Pfam:

PF03024

SMR:

P14207

Uniprot:

P14207

FOR

ELISA Kit for Human FR-beta

Cat.:

E2484h

Price:

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human FR-beta

Cat.:

E2484m

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MSDS:

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Packing:

96T

CLIA Kit for Human FR-beta

Cat.:

U2484h

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Human FR-beta

Cat.:

U2484m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human FR-beta

Cat.:

P2484Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human FR-beta

Cat.:

P2484Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human FR-beta

Protein for Human FR-beta

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Expression of the human placental folate receptor transcript is regulated in human tissues. Organization and full nucleotide sequence of the gene."
Page S.T. , Owen W.C. , Price K. , Elwood P.C.
J. Mol. Biol.229:1175-1183(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];TISSUE SPECIFICITY
2.

"Homologous membrane folate binding proteins in human placenta: cloning and sequence of a cDNA."
Ratnam M. , Marquardt H. , Duhring J.L. , Freisheim J.H.
Biochemistry28:8249-8254(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;FUNCTION;TISSUE SPECIFICITY;GLYCOSYLATION;SUBCELLULAR LOCATION
tissue: Placenta.
3.

"Characterization of the gene encoding a folate-binding protein expressed in human placenta. Identification of promoter activity in a G-rich SP1 site linked with the tandemly repeated GGAAG motif for the ets encoded GA-binding protein."
Sadasivan E. , Cedeno M.M. , Rothenberg S.P.
J. Biol. Chem.269:4725-4735(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Placenta.
4.

Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
Submitted (2005-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Cerebellum.
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Pancreas.
tissue: Placenta.
6.

"Folate coenzyme and antifolate transport proteins in normal and neoplastic cells."
Freisheim J.H. , Price E.M. , Ratnam M.
Adv. Enzyme Regul.29:13-26(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 68-86; 102-120 AND 173-184
7.

"Studies of the role of a particulate folate-binding protein in the uptake of 5-methyltetrahydrofolate by cultured human KB cells."
Antony A.C. , Kane M.A. , Portillo R.M. , Elwood P.C. , Kolhouse J.F.
J. Biol. Chem.260:14911-14917(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
8.

"Preferred sites of glycosylphosphatidylinositol modification in folate receptors and constraints in the primary structure of the hydrophobic portion of the signal."
Yan W. , Ratnam M.
Biochemistry34:14594-14600(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GPI-ANCHOR AT ASN-230
9.

"Proteolysis of the carboxyl-terminal GPI signal independent of GPI modification as a mechanism for selective protein secretion."
Wang J. , Shen F. , Yan W. , Wu M. , Ratnam M.
Biochemistry36:14583-14592(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING
10.

"All-trans retinoic acid is capable of inducing folate receptor beta expression in KG-1 cells."
Xu Y. , Wang T. , Tang R. , Tang S.
Tumor Biol.31:589-595(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY RETINOIC ACID
11.

"Structures of human folate receptors reveal biological trafficking states and diversity in folate and antifolate recognition."
Wibowo A.S. , Singh M. , Reeder K.M. , Carter J.J. , Kovach A.R. , Meng W. , Ratnam M. , Zhang F. , Dann C.E. III
Proc. Natl. Acad. Sci. U.S.A.110:15180-15188(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 24-228 IN COMPLEXES WITH FOLATE AND THE ANTIFOLATES METHOTREXATE; AMINOPTERIN AND PEMETREXED;FUNCTION;GLYCOSYLATION AT ASN-195;DISULFIDE BONDS
12.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] ASN-236

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