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Index > Protein center > FOXC2(Gene name) > Human
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  • FOXC2 (Gene name),
  • Forkhead box protein C2 (Protein name ),  FOXC2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    FOXC2(FKHL14;MFH1);
    Protein name:
    Forkhead box protein C2;
    Alternative:
    Mesenchyme fork head protein 1(MFH-1 protein);Forkhead-related protein FKHL14;Transcription factor FKH-14;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Transcriptional activator. Might be involved in the formation of special mesenchymal tissues.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    501
    Sequence:
    50:
    MQARYSVSDP | NALGVVPYLS | EQNYYRAAGS | YGGMASPMGV | YSGHPEQYSA | 
    100:
    GMGRSYAPYH | HHQPAAPKDL | VKPPYSYIAL | ITMAIQNAPE | KKITLNGIYQ | 
    150:
    FIMDRFPFYR | ENKQGWQNSI | RHNLSLNECF | VKVPRDDKKP | GKGSYWTLDP | 
    200:
    DSYNMFENGS | FLRRRRRFKK | KDVSKEKEER | AHLKEPPPAA | SKGAPATPHL | 
    250:
    ADAPKEAEKK | VVIKSEAASP | ALPVITKVET | LSPESALQGS | PRSAASTPAG | 
    300:
    SPDGSLPEHH | AAAPNGLPGF | SVENIMTLRT | SPPGGELSPG | AGRAGLVVPP | 
    350:
    LALPYAAAPP | AAYGQPCAQG | LEAGAAGGYQ | CSMRAMSLYT | GAERPAHMCV | 
    400:
    PPALDEALSD | HPSGPTSPLS | ALNLAAGQEG | ALAATGHHHQ | HHGHHHPQAP | 
    450:
    PPPPAPQPQP | TPQPGAAAAQ | AASWYLNHSG | DLNHLPGHTF | AAQQQTFPNV | 
    500:
    REMFNSHRLG | IENSTLGESQ | VSGNASCQLP | YRSTPPLYRH | AAPYSYDCTK | 
    501:
    Y
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    MIM:
    SMR:
    Pfam:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Forkhead box protein C2
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    E12449h
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    MSDS:
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    96T
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    ELISA Kit for Human Forkhead box protein C2
    Cat.:
    E12449r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Forkhead box protein C2
    Cat.:
    E12449m
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Forkhead box protein C2
    Cat.:
    U12449r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Forkhead box protein C2
    Cat.:
    U12449h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Forkhead box protein C2
    Cat.:
    U12449m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Forkhead box protein C2
    Cat.:
    P12449Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Forkhead box protein C2
    Polyclonal Antibody for Human Forkhead box protein C2
    Monoclonal Antibody for Human Forkhead box protein C2
    Monoclonal Antibody for Human Forkhead box protein C2
    Monoclonal Antibody for Human Forkhead box protein C2
    Protein for Human Forkhead box protein C2
    Protein for Human Forkhead box protein C2
    Protein for Human Forkhead box protein C2

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    Precision
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    Linearity
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    References
    1. 1.
      "Isolation of the mouse (MFH-1) and human (FKHL 14) mesenchyme fork head-1 genes reveals conservation of their gene and protein structures."
      Miura N. , Iida K. , Kakinuma H. , Yang X.-L. , Sugiyama T.
      Genomics41:489-492(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];FUNCTION
    2. 2.
      NIEHS SNPs program
      Submitted (2009-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT PHE-191
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Mutations in FOXC2 (MFH-1), a forkhead family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndrome."
      Fang J. , Dagenais S.L. , Erickson R.P. , Arlt M.F. , Glynn M.W. , Gorski J.L. , Seaver L.H. , Glover T.W.
      Am. J. Hum. Genet.67:1382-1388(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN LMPH2
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN LYMPHEDEMA SYNDROMES
    6. 6.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-240;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 7.
      "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T. , Yi W. , Lu B. , Park S.K. , Xu T. , Lee J.-D. , Yates J.R. III
      J. Proteome Res.7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-235 AND SER-240;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 8.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-219;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-215; SER-219; SER-232; SER-240 AND SER-288;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-232 AND SER-240;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 12.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-240;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;PHOSPHORYLATION AT SER-219; SER-232; SER-240; THR-247; SER-251; SER-281; SER-288 AND SER-367;IDENTIFICATION BY MASS SPECTROMETRY
    14. 14.
      "Solution structure and dynamics of the DNA-binding domain of the adipocyte-transcription factor FREAC-11."
      van Dongen M.J. , Cederberg A. , Carlsson P. , Enerback S. , Wikstrom M.
      J. Mol. Biol.296:351-359(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 70-162
    15. 15.
      "Analysis of lymphoedema-distichiasis families for FOXC2 mutations reveals small insertions and deletions throughout the gene."
      Bell R. , Brice G. , Child A.H. , Murday V.A. , Mansour S. , Sandy C.J. , Collin J.R.O. , Brady A.F. , Callen D.F. , Burnand K. , Mortimer P. , Jeffery S.
      Hum. Genet.108:546-551(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT LYD LEU-125
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