CPOX ELISA Kit for Human(Homo sapiens) | EIAab.comCPOX ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CPOX(Gene name) > Human

CPOX (Gene name),

Coproporphyrinogen-III oxidase, mitochondrial (Protein name ), HEM6_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CPOX(CPO;CPX);

Protein name:

Coproporphyrinogen-III oxidase, mitochondrial(COX;Coprogen oxidase;Coproporphyrinogenase);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Homodimer.

Function:

Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III.

Subcellular Location:

Mitochondrion intermembrane space

Protein Attributes:

Sequence length:

454

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

454:

DWVR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000264193

String:

P36551

Pfam:

PF01218

KEGG:

hsa:1371

SMR:

P36551

MIM:

121300

UniGene:

Hs.476982

Uniprot:

P36551

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ELISA Kit for Human COX

Cat.:

E12790h

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Manual:

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Packing:

96T

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ELISA Kit for Human COX

Cat.:

E12790m

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Manual:

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Packing:

96T

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ELISA Kit for Human COX

Cat.:

E12790r

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Human COX

Cat.:

U12790r

Price:

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Packing:

96T

CLIA Kit for Human COX

Cat.:

U12790h

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MSDS:

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Packing:

96T

CLIA Kit for Human COX

Cat.:

U12790m

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Packing:

96T

Polyclonal Antibody for Human COX

Cat.:

P12790Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human COX

Cat.:

P12790Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human COX

Cat.:

P12790Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human COX

Protein for Human COX

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Coproporphyrinogen oxidase: gene organization and description of a mutation leading to exon 6 skipping."
Delfau-Larue M.H. , Martasek P. , Grandchamp B.
Hum. Mol. Genet.3:1325-1330(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Placenta.
2.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
tissue: Brain.
tissue: Thalamus.
3.

Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
Submitted (2005-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT ILE-294
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT ILE-294
tissue: Brain.
tissue: Placenta.
tissue: Uterus.
6.

"Molecular cloning, sequencing and expression of cDNA encoding human coproporphyrinogen oxidase."
Taketani S. , Kohno H. , Furukawa T. , Yoshinaga T. , Tokunaga R.
Biochim. Biophys. Acta1183:547-549(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 73-454 (ISOFORM 1)
tissue: Placenta.
7.

"Molecular cloning, sequencing, and functional expression of a cDNA encoding human coproporphyrinogen oxidase."
Martasek P. , Camadro J.-M. , Delfau-Larue M.H. , Dumas J.B. , Montagne J.J. , de Verneuil H. , Labbe P. , Grandchamp B.
Proc. Natl. Acad. Sci. U.S.A.91:3024-3028(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 101-454 (ISOFORM 1);VARIANT HIS-272
tissue: Foreskin.
8.

"The long, but not the short, presequence of human coproporphyrinogen oxidase is essential for its import and sorting to mitochondria."
Susa S. , Daimon M. , Ono H. , Li S. , Yoshida T. , Kato T.
Tohoku J. Exp. Med.200:39-45(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEOLYTIC PROCESSING
9.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.

"Structural basis of hereditary coproporphyria."
Lee D.-S. , Flachsova E. , Bodnarova M. , Demeler B. , Martasek P. , Raman C.S.
Proc. Natl. Acad. Sci. U.S.A.102:14232-14237(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.58 ANGSTROMS) OF 111-453 IN COMPLEX WITH CITRATE;MUTAGENESIS OF 392-TYR--LEU-418;ACTIVE SITE;SUBUNIT
11.

"Homozygous hereditary coproporphyria caused by an arginine to tryptophane substitution in coproporphyrinogen oxidase and common intragenic polymorphisms."
Martasek P. , Nordmann Y. , Grandchamp B.
Hum. Mol. Genet.3:477-480(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HCP TRP-331
12.

"Characterization and expression of cDNA encoding coproporphyrinogen oxidase from a patient with hereditary coproporphyria."
Fujita H. , Kondo M. , Taketani S. , Nomura N. , Furuyama K. , Akagi R. , Nagai T. , Terajima M. , Galbraith R.A. , Sassa S.
Hum. Mol. Genet.3:1807-1810(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HCP SER-189;VARIANTS HIS-272 AND ILE-294
13.

"A molecular defect in coproporphyrinogen oxidase gene causing harderoporphyria, a variant form of hereditary coproporphyria."
Lamoril J. , Martasek P. , Deybach J.-C. , da Silva V. , Grandchamp B. , Nordmann Y.
Hum. Mol. Genet.4:275-278(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HCP GLU-404
14.

"A novel missense mutation in exon 4 of the human coproporphyrinogen oxidase gene in two patients with hereditary coproporphyria."
Daimon M. , Gojyou E. , Sugawara M. , Yamatani K. , Tominaga M. , Sasaki H.
Hum. Genet.99:199-201(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HCP ARG-280
15.

"Three novel mutations in the coproporphyrinogen oxidase gene."
Lamoril J. , Deybach J.-C. , Puy H. , Grandchamp B. , Nordmann Y.
Hum. Mutat.9:78-80(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HCP 162-GLN--ALA-168 DEL AND ASP-295
16.

"Hereditary coproporphyria: exon screening by heteroduplex analysis detects three novel mutations in the coproporphyrinogen oxidase gene."
Schreiber W.E. , Zhang X. , Senz J. , Jamani A.
Hum. Mutat.10:196-200(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HCP LYS-201 AND SER-249
17.

"Systematic analysis of coproporphyrinogen oxidase gene defects in hereditary coproporphyria and mutation update."
Rosipal R. , Lamoril J. , Puy H. , da Silva V. , Gouya L. , de Rooij F.W.M. , Te Velde K. , Nordmann Y. , Martasek P. , Deybach J.-C.
Hum. Mutat.13:44-53(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HCP TRP-197; GLY-390 DEL AND ARG-427
18.

"Two novel mutations and coexistence of the 991C>T and the 1339C>T mutation on a single allele in the coproporphyrinogen oxidase gene in Swedish patients with hereditary coproporphyria."
Wiman A. , Floderus Y. , Harper P.
J. Hum. Genet.47:407-412(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HCP PHE-208; CYS-328; TRP-331 AND CYS-447
19.

"Biochemical and genetic characterization of four cases of hereditary coproporphyria in Spain."
To-Figueras J. , Badenas C. , Enriquez M.T. , Segura S. , Alvarez C. , Mila M. , Lecha M. , Herrero C.
Mol. Genet. Metab.85:160-163(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HCP ALA-135; ARG-214 AND ARG-249
20.

"Dual gene defects involving delta-aminolaevulinate dehydratase and coproporphyrinogen oxidase in a porphyria patient."
Akagi R. , Inoue R. , Muranaka S. , Tahara T. , Taketani S. , Anderson K.E. , Phillips J.D. , Sassa S.
Br. J. Haematol.132:237-243(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HCP ARG-279
21.

Akagi R. , Inoue R. , Muranaka S. , Tahara T. , Taketani S. , Anderson K.E. , Phillips J.D. , Sassa S.
Br. J. Haematol.132:662-662(2006)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM

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