Protein name:
Pro-interleukin-16 ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Homotetramer (Probable). Pro-interleukin-16 interacts (via PDZ 2 domain) with PPP1R12A, PPP1R12B and PPP1R12C. Pro-interleukin-16 interacts with GRIN2A. Pro-interleukin-16 interacts with GABPB1. Pro-interleukin-16 interacts (via PDZ 3 domain) with HDAC3.
Function:
Pro-interleukin-16 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
Subcellular Location:
Pro-interleukin-16
Cytoplasm
Nucleus
Protein Attributes:
50:
MDYSLETTAE | DPWVRISDCI | KNLFSPIMSE | NHNHVPLQPD | APLGEEDGMR |
100:
GHPDGAAAKL | DTTGGGPKAY | KQAGGSTVKK | GPPVAPKPAW | FRQSLKGLRN |
150:
RVPDSRREMA | ASCQPTPTSR | ERPGPPLRAS | SSIKQRISSF | ETFSSAHPPD |
200:
RGAQRLSLQA | SSSSGEAAEL | PRKQEGERAS | GPSGQGAPPT | MEQQRPEPEQ |
250:
LPPASPATSE | ASNPGVSGHP | PLEQQPGQKT | LSSDPDPLSR | LLATQMEGPR |
300:
GPVVKMPSQR | ARSFPLSRTQ | SCEMKPLDEK | TSKLYSISSQ | VSSAVMKSLL |
350:
CLPSSLSFGQ | IPCSPKEGVL | PPTAFSEDPT | NSSAEASASD | TSFSLNLSEL |
400:
REYTEGLSES | TEANDCDHCT | SQPGQSVISL | LSTEELKKLI | EEVKVLDEAT |
450:
LKQLDSIHVT | ILHKEEGAGL | GFSLAGGADL | ENKVITVHRV | FPNGLASQEG |
500:
TIQKGNEVLS | INGKSLKGAT | HNDALAILRQ | AREPRQAVIV | TRRPTLEATT |
550:
DLNSSTDSSG | SASVTSDVSI | ESAEATVCTV | TLEKTSAGLG | FSLEGGKGSL |
600:
HGDKPLTVNR | IFKGLASEQS | DTVQPGDEIV | HLAGTAMQGL | TRFEAWNIIK |
627:
ALPDGPVTIV | LRRKSLQSKG | TPAAGDP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Mouse
ELISA Kit for Bovine Pro-interleukin-16
ELISA Kit for Bovine Pro-interleukin-16
ELISA Kit for Bovine Pro-interleukin-16
CLIA Kit for Bovine Pro-interleukin-16
CLIA Kit for Bovine Pro-interleukin-16
CLIA Kit for Bovine Pro-interleukin-16
Polyclonal Antibody for Bovine Pro-interleukin-16
Polyclonal Antibody for Bovine Pro-interleukin-16
Polyclonal Antibody for Bovine Pro-interleukin-16
Monoclonal Antibody for Bovine Pro-interleukin-16
Monoclonal Antibody for Bovine Pro-interleukin-16
Monoclonal Antibody for Bovine Pro-interleukin-16
Protein for Bovine Pro-interleukin-16
Protein for Bovine Pro-interleukin-16
Protein for Bovine Pro-interleukin-16
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]