Gene name:
IL1RAP (C3orf13;IL1R3) ;
Protein name:
Interleukin-1 receptor accessory protein (IL-1 receptor accessory protein;IL-1RAcP) ;
Alternative:
Interleukin-1 receptor 3 (IL-1R-3;IL-1R3) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
The signaling-competent complex is a heterodimer of IL1R2 and IL1RAP bound to IL1B.
Function:
Mediates interleukin-1-dependent activation of NF-kappa-B. Isoform 1 is part of the membrane-bound form of the IL-1 receptor. Signaling involves formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. Isoform 2 modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.
Subcellular Location:
Isoform 3
Secreted
Protein Attributes:
50:
MTLLWCVVSL | YFYGILQSDA | SERCDDWGLD | TMRQIQVFED | EPARIKCPLF |
100:
EHFLKFNYST | AHSAGLTLIW | YWTRQDRDLE | EPINFRLPEN | RISKEKDVLW |
150:
FRPTLLNDTG | NYTCMLRNTT | YCSKVAFPLE | VVQKDSCFNS | PMKLPVHKLY |
200:
IEYGIQRITC | PNVDGYFPSS | VKPTITWYMG | CYKIQNFNNV | IPEGMNLSFL |
250:
IALISNNGNY | TCVVTYPENG | RTFHLTRTLT | VKVVGSPKNA | VPPVIHSPND |
300:
HVVYEKEPGE | ELLIPCTVYF | SFLMDSRNEV | WWTIDGKKPD | DITIDVTINE |
350:
SISHSRTEDE | TRTQILSIKK | VTSEDLKRSY | VCHARSAKGE | VAKAAKVKQK |
400:
VPAPRYTVEL | ACGFGATVLL | VVILIVVYHV | YWLEMVLFYR | AHFGTDETIL |
450:
DGKEYDIYVS | YARNAEEEEF | VLLTLRGVLE | NEFGYKLCIF | DRDSLPGGIV |
500:
TDETLSFIQK | SRRLLVVLSP | NYVLQGTQAL | LELKAGLENM | ASRGNINVIL |
550:
VQYKAVKETK | VKELKRAKTV | LTVIKWKGEK | SKYPQGRFWK | QLQVAMPVKK |
570:
SPRRSSSDEQ | GLSYSSLKNV |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Human IL-1 receptor accessory protein
ELISA Kit for Human IL-1 receptor accessory protein
ELISA Kit for Human IL-1 receptor accessory protein
CLIA Kit for Human IL-1 receptor accessory protein
CLIA Kit for Human IL-1 receptor accessory protein
CLIA Kit for Human IL-1 receptor accessory protein
Polyclonal Antibody for Human IL-1 receptor accessory protein
Polyclonal Antibody for Human IL-1 receptor accessory protein
Polyclonal Antibody for Human IL-1 receptor accessory protein
Monoclonal Antibody for Human IL-1 receptor accessory protein
Monoclonal Antibody for Human IL-1 receptor accessory protein
Monoclonal Antibody for Human IL-1 receptor accessory protein
Protein for Human IL-1 receptor accessory protein
Protein for Human IL-1 receptor accessory protein
Protein for Human IL-1 receptor accessory protein
R&D Technical Data
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Precision
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Recovery
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Linearity
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Placenta .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Skin .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cervix carcinoma .
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