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Index > Protein center > Jag1(Gene name) > Mouse
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  • Jag1 (Gene name),
  • Protein jagged-1 (Protein name ),  JAG1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Jag1;
    Protein name:
    Protein jagged-1(Jagged1);
    Alternative:

    CD:
    CD339;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with NOTCH1, NOTCH2 and NOTCH3.
    Function:
    Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). May regulate fibroblast growth factor-induced angiogenesis.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    1218
    Sequence:
    50:
    MRSPRTRGRP | GRPLSLLLAL | LCALRAKVCG | ASGQFELEIL | SMQNVNGELQ | 
    100:
    NGNCCGGVRN | PGDRKCTRDE | CDTYFKVCLK | EYQSRVTAGG | PCSFGSGSTP | 
    150:
    VIGGNTFNLK | ASRGNDRNRI | VLPFSFAWPR | SYTLLVEAWD | SSNDTIQPDS | 
    200:
    IIEKASHSGM | INPSRQWQTL | KQNTGIAHFE | YQIRVTCDDH | YYGFGCNKFC | 
    250:
    RPRDDFFGHY | ACDQNGNKTC | MEGWMGPDCN | KAICRQGCSP | KHGSCKLPGD | 
    300:
    CRCQYGWQGL | YCDKCIPHPG | CVHGTCNEPW | QCLCETNWGG | QLCDKDLNYC | 
    350:
    GTHQPCLNRG | TCSNTGPDKY | QCSCPEGYSG | PNCEIAEHAC | LSDPCHNRGS | 
    400:
    CKETSSGFEC | ECSPGWTGPT | CSTNIDDCSP | NNCSHGGTCQ | DLVNGFKCVC | 
    450:
    PPQWTGKTCQ | LDANECEAKP | CVNARSCKNL | IASYYCDCLP | GWMGQNCDIN | 
    500:
    INDCLGQCQN | DASCRDLVNG | YRCICPPGYA | GDHCERDIDE | CASNPCLNGG | 
    550:
    HCQNEINRFQ | CLCPTGFSGN | LCQLDIDYCE | PNPCQNGAQC | YNRASDYFCK | 
    600:
    CPEDYEGKNC | SHLKDHCRTT | TCEVIDSCTV | AMASNDTPEG | VRYISSNVCG | 
    650:
    PHGKCKSQSG | GKFTCDCNKG | FTGTYCHENI | NDCESNPCKN | GGTCIDGVNS | 
    700:
    YKCICSDGWE | GAHCENNIND | CSQNPCHYGG | TCRDLVNDFY | CDCKNGWKGK | 
    750:
    TCHSRDSQCD | EATCNNGGTC | YDEVDTFKCM | CPGGWEGTTC | NIARNSSCLP | 
    800:
    NPCHNGGTCV | VNGDSFTCVC | KEGWEGPICT | QNTNDCSPHP | CYNSGTCVDG | 
    850:
    DNWYRCECAP | GFAGPDCRIN | INECQSSPCA | FGATCVDEIN | GYQCICPPGH | 
    900:
    SGAKCHEVSG | RSCITMGRVI | LDGAKWDDDC | NTCQCLNGRV | ACSKVWCGPR | 
    950:
    PCRLHKSHNE | CPSGQSCIPV | LDDQCFVRPC | TGVGECRSSS | LQPVKTKCTS | 
    1000:
    DSYYQDNCAN | ITFTFNKEMM | SPGLTTEHIC | SELRNLNILK | NVSAEYSIYI | 
    1050:
    ACEPSLSANN | EIHVAISAED | IRDDGNPVKE | ITDKIIDLVS | KRDGNSSLIA | 
    1100:
    AVAEVRVQRR | PLKNRTDFLV | PLLSSVLTVA | WVCCLVTAFY | WCVRKRRKPS | 
    1150:
    SHTHSAPEDN | TTNNVREQLN | QIKNPIEKHG | ANTVPIKDYE | NKNSKMSKIR | 
    1200:
    THNSEVEEDD | MDKHQQKVRF | AKQPVYTLVD | REEKAPSGTP | TKHPNWTNKQ | 
    1218:
    DNRDLESAQS | LNRMEYIV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Jagged1
    Cat.:
    E2164r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Jagged1
    Cat.:
    E2164h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Jagged1
    Cat.:
    E2164m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Jagged1
    Cat.:
    U2164r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Jagged1
    Cat.:
    U2164h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Jagged1
    Cat.:
    U2164m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Jagged1
    Cat.:
    P2164Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Jagged1
    Cat.:
    P2164Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Jagged1
    Cat.:
    P2164Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Jagged1
    Monoclonal Antibody for Mouse Jagged1
    Monoclonal Antibody for Mouse Jagged1
    Protein for Mouse Jagged1
    Protein for Mouse Jagged1
    Protein for Mouse Jagged1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Mouse Jagged1 physically interacts with Notch2 and other Notch receptors: assessment by quantitative methods."
      Shimizu K. , Chiba S. , Kumano K. , Hosoya N. , Takahashi T. , Kanda Y. , Hamada Y. , Yazaki Y. , Hirai H.
      J. Biol. Chem.274:32961-32969(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];RECEPTOR INTERACTION
      strain: Swiss Webster / NIH.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Brain.
    3. 3.
      "The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome."
      Loomes K.M. , Underkoffler L.A. , Morabito J. , Gottlieb S. , Piccoli D.A. , Spinner N.B. , Baldwin H.S. , Oakey R.J.
      Hum. Mol. Genet.8:2443-2449(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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