LAMA3 ELISA Kit for Human(Homo sapiens) | EIAab.comLAMA3 ELISA Kit for Human(Homo sapiens)

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LAMA3 (Gene name),

Laminin subunit alpha-3 (Protein name ), LAMA3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

LAMA3(LAMNA);

Protein name:

Laminin subunit alpha-3;

Alternative:

Epiligrin subunit alpha;Epiligrin 170 kDa subunit(E170);Laminin-5 subunit alpha;Kalinin subunit alpha;Laminin-7 subunit alpha;Laminin-6 subunit alpha;Nicein subunit alpha;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Alpha-3 is a subunit of laminin-5 (laminin-332 or epiligrin/kalinin/nicein), laminin-6 (laminin-311 or K-laminin) and laminin-7 (laminin-321 or KS-laminin).

Function:

Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes.

Subcellular Location:

Secreted extracellular space extracellular matrix basement membrane Major component.

Protein Attributes:

Sequence length:

3333

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GCLRNIHVNH | IPVPVTEALE | VQGPVSLNGC | PDQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q16787

MIM:

226700

UniGene:

Hs.436367

String:

Q16787

KEGG:

hsa:3909

STRING:

9606.ENSP00000324532

Pfam:

PF00052

Uniprot:

Q16787

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ELISA Kit for Human Laminin subunit alpha-3

Cat.:

E1345h

Price:

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Manual:

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Packing:

96T

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ELISA Kit for Human Laminin subunit alpha-3

Cat.:

E1345m

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Human Laminin subunit alpha-3

Cat.:

U1345h

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Laminin subunit alpha-3

Cat.:

U1345m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Laminin subunit alpha-3

Cat.:

P1345Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Laminin subunit alpha-3

Cat.:

P1345Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Laminin subunit alpha-3

Protein for Human Laminin subunit alpha-3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"An unusual N-terminal deletion of the laminin alpha3a isoform leads to the chronic granulation tissue disorder laryngo-onycho-cutaneous syndrome."
McLean W.H.I. , Irvine A.D. , Hamill K.J. , Whittock N.V. , Coleman-Campbell C.M. , Mellerio J.E. , Ashton G.S. , Dopping-Hepenstal P.J.H. , Eady R.A.J. , Jamil T. , Phillips R.J. , Shabbir S.G. , Haroon T.S. , Khurshid K. , Moore J.E. , Page B. , Darling J. , Atherton D.J. , more...
Hum. Mol. Genet.12:2395-2409(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3 AND 4);DISEASE
2.

"Characterization of laminin 5B and NH2-terminal proteolytic fragment of its alpha3B chain: promotion of cellular adhesion, migration, and proliferation."
Kariya Y. , Yasuda C. , Nakashima Y. , Ishida K. , Tsubota Y. , Miyazaki K.
J. Biol. Chem.279:24774-24784(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 2);VARIANT GLY-2834
3.

Stockwell T.B. , Busam D.A. , Ferriera S.M. , Brownley A.N. , Strausberg R.L. , Kirkness E.F. , Rogers Y.-H. , Levy S.
Submitted (2007-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"DNA sequence and analysis of human chromosome 18."
Nusbaum C. , Zody M.C. , Borowsky M.L. , Kamal M. , Kodira C.D. , Taylor T.D. , Whittaker C.A. , Chang J.L. , Cuomo C.A. , Dewar K. , FitzGerald M.G. , Yang X. , Abouelleil A. , Allen N.R. , Anderson S. , Bloom T. , Bugalter B. , Butler J. , more...
Nature437:551-555(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"Cloning of the laminin alpha 3 chain gene (LAMA3) and identification of a homozygous deletion in a patient with Herlitz junctional epidermolysis bullosa."
Vidal F. , Baudoin C. , Miquel C. , Galliano M.-F. , Christiano A.M. , Uitto J. , Ortonne J.-P. , Meneguzzi G.
Genomics30:273-280(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-2858 (ISOFORM 1);NUCLEOTIDE SEQUENCE [MRNA] OF 1528-2858 (ISOFORMS 1/2)
tissue: Keratinocyte.
6.

"Mutation in LAMA3 gene in a patient affected by H-Jeb."
Aberdam D. , Vidal F. , Baudoin C. , Miquel C. , Ortonne J.-P. , Meneguzzi G.
Submitted (1995-02) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1528-3333 (ISOFORMS 1/2);VARIANT GLY-2834
7.

"Cloning of the LamA3 gene encoding the alpha 3 chain of the adhesive ligand epiligrin. Expression in wound repair."
Ryan M.C. , Tizard R. , Vandevanter D.R. , Carter W.G.
J. Biol. Chem.269:22779-22787(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT GLY-2834
tissue: Keratinocyte.
8.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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