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Index > Protein center > LCN1(Gene name) > Human
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  • LCN1 (Gene name),
  • Lipocalin-1 (Protein name ),  LCN1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    LCN1(VEGP);
    Protein name:
    Lipocalin-1;
    Alternative:
    Tear prealbumin(TP);Tear lipocalin(Tlc);Von Ebner gland protein(VEG protein);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer (By similarity). Binds to LMBR1L which may mediate its endocytosis.
    Function:
    Could play a role in taste reception. Could be necessary for the concentration and delivery of sapid molecules in the gustatory system. Can bind various ligands, with chemical structures ranging from lipids and retinoids to the macrocyclic antibiotic rifampicin and even to microbial siderophores. Exhibits an extremely wide ligand pocket.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    176
    Sequence:
    50:
    MKPLLLAVSL | GLIAALQAHH | LLASDEEIQD | VSGTWYLKAM | TVDREFPEMN | 
    100:
    LESVTPMTLT | TLEGGNLEAK | VTMLISGRCQ | EVKAVLEKTD | EPGKYTADGG | 
    150:
    KHVAYIIRSH | VKDHYIFYCE | GELHGKPVRG | VKLVGRDPKN | NLEALEDFEK | 
    176:
    AAGARGLSTE | SILIPRQSET | CSPGSD
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    Pfam:
    MIM:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Lipocalin-1
    Cat.:
    E1413h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Lipocalin-1
    Cat.:
    E1413p
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Lipocalin-1
    Cat.:
    U1413p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Lipocalin-1
    Cat.:
    U1413h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Lipocalin-1
    Cat.:
    P1413Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Lipocalin-1
    Monoclonal Antibody for Human Lipocalin-1
    Monoclonal Antibody for Human Lipocalin-1
    Protein for Human Lipocalin-1
    Protein for Human Lipocalin-1

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Molecular cloning of human von Ebner's gland protein, a member of the lipocalin superfamily highly expressed in lingual salivary glands."
      Blaeker M. , Kock K. , Ahlers C. , Buck F. , Schmale H.
      Biochim. Biophys. Acta1172:131-137(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Tongue.
    2. 2.
      "cDNA cloning and sequencing reveals human tear prealbumin to be a member of the lipophilic-ligand carrier protein superfamily."
      Redl B. , Holzfeind P. , Lottspeich F.
      J. Biol. Chem.267:20282-20287(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Tear.
    3. 3.
      "Cloning of a human lacrimal lipocalin secreted in tears."
      Lassagne H. , Gachon A.-M.
      Exp. Eye Res.56:605-609(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Tear.
    4. 4.
      "Structural organization of the gene encoding the human lipocalin tear prealbumin and synthesis of the recombinant protein in Escherichia coli."
      Holzfeind P. , Redl B.
      Gene139:177-183(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 19-38
      tissue: Nasal mucus.
    9. 9.
      "Molecular cloning of a novel lipocalin-1 interacting human cell membrane receptor using phage display."
      Wojnar P. , Lechner M. , Merschak P. , Redl B.
      J. Biol. Chem.276:20206-20212(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LMBR1L
      tissue: Pituitary.
    10. 10.
      "Antisense down-regulation of lipocalin-interacting membrane receptor expression inhibits cellular internalization of lipocalin-1 in human NT2 cells."
      Wojnar P. , Lechner M. , Redl B.
      J. Biol. Chem.278:16209-16215(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LMBR1L;ENDOCYTOSIS
    11. 11.
      "The 1.8-A crystal structure of human tear lipocalin reveals an extended branched cavity with capacity for multiple ligands."
      Breustedt D.A. , Korndorfer I.P. , Redl B. , Skerra A.
      J. Biol. Chem.280:484-493(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 23-175
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