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Index > Protein center > LHB(Gene name) > Human
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  • LHB (Gene name),
  • Lutropin subunit beta (Protein name ),  LSHB_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    LHB;
    Protein name:
    Lutropin subunit beta(Lutropin beta chain);
    Alternative:
    Luteinizing hormone subunit beta(LH-B;LSH-B;LSH-beta);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.
    Function:
    Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    141
    Sequence:
    50:
    MEMLQGLLLL | LLLSMGGAWA | SREPLRPWCH | PINAILAVEK | EGCPVCITVN | 
    100:
    TTICAGYCPT | MMRVLQAVLP | PLPQVVCTYR | DVRFESIRLP | GCPRGVDPVV | 
    141:
    SFPVALSCRC | GPCRRSTSDC | GGPKDHPLTC | DHPQLSGLLF | L
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    MIM:
    Pfam:
    String:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Lutropin beta chain
    Cat.:
    E1174h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Lutropin beta chain
    Cat.:
    E1174r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Lutropin beta chain
    Cat.:
    E1174d
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Lutropin beta chain
    MSDS:
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    ELISA Kit for Human Lutropin beta chain
    Cat.:
    E1174p
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Lutropin beta chain
    Cat.:
    E1174s
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Lutropin beta chain
    Cat.:
    E1174b
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Lutropin beta chain
    Cat.:
    E1174m
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human Lutropin beta chain
    Cat.:
    U1174m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human Lutropin beta chain
    Cat.:
    U1174d
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Lutropin beta chain
    Cat.:
    U1174r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Lutropin beta chain
    MSDS:
    Please sign in first.
    CLIA Kit for Human Lutropin beta chain
    Cat.:
    U1174p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Lutropin beta chain
    Cat.:
    U1174b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Lutropin beta chain
    Cat.:
    U1174h
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Lutropin beta chain
    Polyclonal Antibody for Human Lutropin beta chain
    Cat.:
    P1174Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Lutropin beta chain
    Polyclonal Antibody for Human Lutropin beta chain
    Polyclonal Antibody for Human Lutropin beta chain
    Cat.:
    P1174Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Lutropin beta chain
    Polyclonal Antibody for Human Lutropin beta chain
    Cat.:
    P1174Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Lutropin beta chain
    Monoclonal Antibody for Human Lutropin beta chain
    Monoclonal Antibody for Human Lutropin beta chain
    Monoclonal Antibody for Human Lutropin beta chain
    Monoclonal Antibody for Human Lutropin beta chain
    Monoclonal Antibody for Human Lutropin beta chain
    Monoclonal Antibody for Human Lutropin beta chain
    Protein for Human Lutropin beta chain
    Protein for Human Lutropin beta chain
    Protein for Human Lutropin beta chain
    Protein for Human Lutropin beta chain
    Protein for Human Lutropin beta chain
    Protein for Human Lutropin beta chain
    Protein for Human Lutropin beta chain

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    References
    1. 1.
      "Evolution of the genes for the beta subunits of human chorionic gonadotropin and luteinizing hormone."
      Talmadge K. , Vamvakopoulos N.C. , Fiddes J.C.
      Nature307:37-40(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "Human pituitary lutropin. Isolation, properties, and the complete amino acid sequence of the beta-subunit."
      Sairam M.R. , Li C.H.
      Biochim. Biophys. Acta412:70-81(1975) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 21-141
    3. 3.
      "The primary structure of the hormone-specific, beta subunit of human pituitary luteinizing hormone (hLH)."
      Shome B. , Parlow A.F.
      J. Clin. Endocrinol. Metab.36:618-621(1973) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY PROTEIN SEQUENCE OF 21-141
    4. 4.
      "Structure and significance of human luteinizing hormone-beta core fragment purified from human pituitary extracts."
      Birken S. , Chen Y. , Gawinowicz M.A. , Agosto G.M. , Canfield R.E. , Hartree A.S.
      Endocrinology133:985-989(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 26-40 AND 75-89
      tissue: Pituitary.
    5. 5.
      "Human luteinizing hormone. The amino acid sequence of the subunit."
      Closset J. , Hennen G. , Lequin R.M.
      FEBS Lett.29:97-100(1973) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY PARTIAL PROTEIN SEQUENCE
    6. 6.
      "NMR investigations of the N-linked oligosaccharides at individual glycosylation sites of human lutropin."
      Weisshaar G. , Hiyama J. , Renwick A.G.C. , Nimtz M.
      Eur. J. Biochem.195:257-268(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE OF CARBOHYDRATE
    7. 7.
      "Structure of a receptor-binding fragment from human luteinizing hormone beta-subunit determined by [1H]- and [15N]nuclear magnetic resonance spectroscopy."
      Keutmann H.T. , Hua Q.-X. , Weiss M.A.
      Mol. Endocrinol.6:904-913(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 58-77
    8. 8.
      "Hypogonadism caused by a single amino acid substitution in the beta subunit of luteinizing hormone."
      Weiss J. , Axelrod L. , Whitcomb R.W. , Harris P.E. , Crowley W.F. Jr. , Jameson J.L.
      N. Engl. J. Med.326:179-183(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HGON-LHB ARG-74
    9. 9.
      "A new molecular variant of luteinizing hormone associated with female infertility."
      Liao W.X. , Roy A.C. , Chan C. , Arulkumaran S. , Ratnam S.S.
      Fertil. Steril.69:102-106(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT SER-122
    10. 10.
      "Increased prevalence of luteinizing hormone beta-subunit variant in Japanese infertility patients."
      Takahashi K. , Kurioka H. , Ozaki T. , Kanasaki H. , Kohsaka M. , Miyazaki K. , Karino K.
      Hum. Reprod.13:3338-3344(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ARG-28 AND THR-35
    11. 11.
      "A novel Ala(-3)Thr mutation in the signal peptide of human luteinizing hormone beta-subunit: potentiation of the inositol phosphate signalling pathway and attenuation of the adenylate cyclase pathway by recombinant variant hormone."
      Jiang M. , Lamminen T. , Pakarinen P. , Hellman J. , Manna P. , Herrera R.J. , Huhtaniemi I.
      Mol. Hum. Reprod.8:201-212(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THR-18
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