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Index > Protein center > MEP1A(Gene name) > Human
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  • MEP1A (Gene name),
  • Meprin A subunit alpha (Protein name ),  MEP1A_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    MEP1A;
    Protein name:
    Meprin A subunit alpha;
    Alternative:
    N-benzoyl-L-tyrosyl-P-amino-benzoic acid hydrolase subunit alpha;Endopeptidase-2;PPH alpha;PABA peptide hydrolase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotetramer consisting of disulfide-linked alpha subunits, homooligomer consisting of disulfide-linked alpha subunit homodimers, or heterotetramer of two alpha and two beta subunits formed by non-covalent association of two disulfide-linked heterodimers (By similarity). Interacts with MBL2 through its carbohydrate moiety. This interaction may inhibit its catalytic activity.
    Function:
    N/A
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    746
    Sequence:
    50:
    MAWIRSTCIL | FFTLLFAHIA | AVPIKYLPEE | NVHDADFGEQ | KDISEINLAA | 
    100:
    GLDLFQGDIL | LQKSRNGLRD | PNTRWTFPIP | YILADNLGLN | AKGAILYAFE | 
    150:
    MFRLKSCVDF | KPYEGESSYI | IFQQFDGCWS | EVGDQHVGQN | ISIGQGCAYK | 
    200:
    AIIEHEILHA | LGFYHEQSRT | DRDDYVNIWW | DQILSGYQHN | FDTYDDSLIT | 
    250:
    DLNTPYDYES | LMHYQPFSFN | KNASVPTITA | KIPEFNSIIG | QRLDFSAIDL | 
    300:
    ERLNRMYNCT | TTHTLLDHCT | FEKANICGMI | QGTRDDTDWA | HQDSAQAGEV | 
    350:
    DHTLLGQCTG | AGYFMQFSTS | SGSAEEAALL | ESRILYPKRK | QQCLQFFYKM | 
    400:
    TGSPSDRLVV | WVRRDDSTGN | VRKLVKVQTF | QGDDDHNWKI | AHVVLKEEQK | 
    450:
    FRYLFQGTKG | DPQNSTGGIY | LDDITLTETP | CPTGVWTVRN | FSQVLENTSK | 
    500:
    GDKLQSPRFY | NSEGYGFGVT | LYPNSRESSG | YLRLAFHVCS | GENDAILEWP | 
    550:
    VENRQVIITI | LDQEPDVRNR | MSSSMVFTTS | KSHTSPAIND | TVIWDRPSRV | 
    600:
    GTYHTDCNCF | RSIDLGWSGF | ISHQMLKRRS | FLKNDDLIIF | VDFEDITHLS | 
    650:
    QTEVPTKGKR | LSPQGLILQG | QEQQVSEEGS | GKAMLEEALP | VSLSQGQPSR | 
    700:
    QKRSVENTGP | LEDHNWPQYF | RDPCDPNPCQ | NDGICVNVKG | MASCRCISGH | 
    746:
    AFFYTGERCQ | AVQVHGSVLG | MVIGGTAGVI | FLTFSIIAIL | SQRPRK
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    MIM:
    Pfam:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Meprin A subunit alpha
    Cat.:
    E2226h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Meprin A subunit alpha
    Cat.:
    E2226r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Meprin A subunit alpha
    Cat.:
    E2226m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Meprin A subunit alpha
    Cat.:
    U2226r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Meprin A subunit alpha
    Cat.:
    U2226h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Meprin A subunit alpha
    Cat.:
    U2226m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Meprin A subunit alpha
    Cat.:
    P2226Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Meprin A subunit alpha
    Cat.:
    P2226Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Meprin A subunit alpha
    Cat.:
    P2226Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Meprin A subunit alpha
    Monoclonal Antibody for Human Meprin A subunit alpha
    Monoclonal Antibody for Human Meprin A subunit alpha
    Protein for Human Meprin A subunit alpha
    Protein for Human Meprin A subunit alpha
    Protein for Human Meprin A subunit alpha

    R&D Technical Data
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    Precision
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    Linearity
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    References
    1. 1.
      Sterchi E.E.
      Submitted (1994-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT SER-606
      tissue: Jejunum.
    2. 2.
      "Expression of human meprin alpha."
      Haun R.S.
      Submitted (2002-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Small intestine.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS LEU-469 AND MET-726
      tissue: Colon.
      tissue: Small intestine.
    4. 4.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS LEU-469 AND GLY-476
    7. 7.
      "Cloning of the PABA peptide hydrolase alpha subunit (PPH alpha) from human small intestine and its expression in COS-1 cells."
      Dumermuth E. , Eldering J.A. , Gruenberg J. , Jiang W. , Sterchi E.E.
      FEBS Lett.335:367-375(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 32-746;VARIANT SER-606
      tissue: Jejunum.
    8. 8.
      "Human and mouse homo-oligomeric meprin A metalloendopeptidase: substrate and inhibitor specificities."
      Bylander J.E. , Bertenshaw G.P. , Matters G.L. , Hubbard S.J. , Bond J.S.
      Biol. Chem.388:1163-1172(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION;BIOPHYSICOCHEMICAL PROPERTIES
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