Gene name:
MUM1 (EXPAND1) ;
Protein name:
PWWP domain-containing protein MUM1 ;
Alternative:
Protein expandere ;Mutated melanoma-associated antigen 1 (MUM-1) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with TP53BP1 (via BRCT domain); the interaction is not dependent on its phosphorylation status. Binds nucleosomes.
Function:
Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
Subcellular Location:
Nucleus
Recuited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.
Protein Attributes:
50:
MADAKYVLCR | WEKRLWPAKV | LARTATSTKN | KRRKEYFLAV | QILSLEEKIK |
100:
VKSTEVEILE | KSQIEAIASS | LASQNEVPAA | PLEELAYRRS | LRVALDVLSE |
150:
GSIWSQESSA | GTGRADRSLR | GKPMEHVSSP | CDSNSSSLPR | GDVLGSSRPH |
200:
RRRPCVQQSL | SSSFTCEKDP | ECKVDHKKGL | RKSENPRGPL | VLPAGGGAQD |
250:
ESGSRIHHKN | WTLASKRGGN | SAQKASLCLN | GSSLSEDDTE | RDMGSKGGSW |
300:
AAPSLPSGVR | EDDPCANAEG | HDPGLPLGSL | TAPPAPEPSA | CSEPGECPAK |
350:
KRPRLDGSQR | PPAVQLEPMA | AGAAPSPGPG | PGPRESVTPR | STARLGPPPS |
400:
HASADATRCL | PCPDSQKLEK | ECQSSEESMG | SNSMRSILEE | DEEDEEPPRV |
450:
LLYHEPRSFE | VGMLVWHKHK | KYPFWPAVVK | SVRQRDKKAS | VLYIEGHMNP |
500:
KMKGFTVSLK | SLKHFDCKEK | QTLLNQARED | FNQDIGWCVS | LITDYRVRLG |
550:
CGSFAGSFLE | YYAADISYPV | RKSIQQDVLG | TKLPQLSKGS | PEEPVVGCPL |
600:
GQRQPCRKML | PDRSRAARDR | ANQKLVEYIV | KAKGAESHLR | AILKSRKPSR |
650:
WLQTFLSSSQ | YVTCVETYLE | DEGQLDLVVK | YLQGVYQEVG | AKVLQRTNGD |
700:
RIRFILDVLL | PEAIICAISA | VDEVDYKTAE | EKYIKGPSLS | YREKEIFDNQ |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Bovine
Mouse
ELISA Kit for Human PWWP domain-containing protein MUM1
ELISA Kit for Human PWWP domain-containing protein MUM1
ELISA Kit for Human PWWP domain-containing protein MUM1
ELISA Kit for Human PWWP domain-containing protein MUM1
CLIA Kit for Human PWWP domain-containing protein MUM1
CLIA Kit for Human PWWP domain-containing protein MUM1
CLIA Kit for Human PWWP domain-containing protein MUM1
CLIA Kit for Human PWWP domain-containing protein MUM1
Polyclonal Antibody for Human PWWP domain-containing protein MUM1
Polyclonal Antibody for Human PWWP domain-containing protein MUM1
Polyclonal Antibody for Human PWWP domain-containing protein MUM1
Polyclonal Antibody for Human PWWP domain-containing protein MUM1
Monoclonal Antibody for Human PWWP domain-containing protein MUM1
Monoclonal Antibody for Human PWWP domain-containing protein MUM1
Monoclonal Antibody for Human PWWP domain-containing protein MUM1
Monoclonal Antibody for Human PWWP domain-containing protein MUM1
Protein for Human PWWP domain-containing protein MUM1
Protein for Human PWWP domain-containing protein MUM1
Protein for Human PWWP domain-containing protein MUM1
Protein for Human PWWP domain-containing protein MUM1
R&D Technical Data
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Precision
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Recovery
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Linearity
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3);VARIANT ARG-219
tissue :
Brain .
tissue :
PNS .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-411;VARIANT ARG-219
tissue :
Melanoma .
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[
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 421-710 (ISOFORMS 1/2)
tissue :
Placenta .
tissue :
Thyroid .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;IDENTIFICATION BY MASS SPECTROMETRY;SUBCELLULAR LOCATION;DOMAIN PWWP;INTERACTION WITH TP53BP1 AND NUCLEOSOMES
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.82 ANGSTROMS) OF 405-538;INTERACTION WITH TRIMETHYLATED HISTONE H3