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Index > Protein center > PTGDR(Gene name) > Human
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  • PTGDR (Gene name),
  • Prostaglandin D2 receptor (Protein name ),  PD2R_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PTGDR;
    Protein name:
    Prostaglandin D2 receptor(PGD receptor;PGD2 receptor);
    Alternative:
    Prostanoid DP receptor;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    359
    Sequence:
    50:
    MKSPFYRCQN | TTSVEKGNSA | VMGGVLFSTG | LLGNLLALGL | LARSGLGWCS | 
    100:
    RRPLRPLPSV | FYMLVCGLTV | TDLLGKCLLS | PVVLAAYAQN | RSLRVLAPAL | 
    150:
    DNSLCQAFAF | FMSFFGLSST | LQLLAMALEC | WLSLGHPFFY | RRHITLRLGA | 
    200:
    LVAPVVSAFS | LAFCALPFMG | FGKFVQYCPG | TWCFIQMVHE | EGSLSVLGYS | 
    250:
    VLYSSLMALL | VLATVLCNLG | AMRNLYAMHR | RLQRHPRSCT | RDCAEPRADG | 
    300:
    REASPQPLEE | LDHLLLLALM | TVLFTMCSLP | VIYRAYYGAF | KDVKEKNRTS | 
    350:
    EEAEDLRALR | FLSVISIVDP | WIFIIFRSPV | FRIFFHKIFI | RPLRYRSRCS | 
    359:
    NSTNMESSL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    Pfam:
    UniGene:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human PGD receptor
    Cat.:
    E15002h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human PGD receptor
    MSDS:
    Please sign in first.
    ELISA Kit for Human PGD receptor
    MSDS:
    Please sign in first.
    ELISA Kit for Human PGD receptor
    Cat.:
    E15002m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human PGD receptor
    MSDS:
    Please sign in first.
    CLIA Kit for Human PGD receptor
    MSDS:
    Please sign in first.
    CLIA Kit for Human PGD receptor
    MSDS:
    Please sign in first.
    CLIA Kit for Human PGD receptor
    Cat.:
    U15002h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human PGD receptor
    Polyclonal Antibody for Human PGD receptor
    Polyclonal Antibody for Human PGD receptor
    Polyclonal Antibody for Human PGD receptor
    Monoclonal Antibody for Human PGD receptor
    Monoclonal Antibody for Human PGD receptor
    Monoclonal Antibody for Human PGD receptor
    Monoclonal Antibody for Human PGD receptor
    Protein for Human PGD receptor
    Protein for Human PGD receptor
    Protein for Human PGD receptor
    Protein for Human PGD receptor

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    References
    1. 1.
      "Molecular cloning and characterization of the human prostanoid DP receptor."
      Boie Y. , Sawyer N. , Slipetz D.M. , Metters K.M. , Abramovitz M.
      J. Biol. Chem.270:18910-18916(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1)
    2. 2.
      Martin A.L. , Kaighin V.A. , Aronstam R.S.
      Submitted (2007-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Small intestine.
    3. 3.
      SeattleSNPs variation discovery resource
      Submitted (2006-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS CYS-7; GLU-198; ALA-301 AND GLN-332
    4. 4.
      "The DNA sequence and analysis of human chromosome 14."
      Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
      Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    7. 7.
      "Pharmacological and cardiovascular properties of a hydantoin derivative, BW 245 C, with high affinity and selectivity for PGD2 receptors."
      Town M.H. , Casals-Stenzel J. , Schillinger E.
      Prostaglandins25:13-28(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    8. 8.
      "Pharmacology and autoradiography of human DP prostanoid receptors using [(3)H]-BWA868C, a DP receptor-selective antagonist radioligand."
      Sharif N.A. , Williams G.W. , Davis T.L.
      Br. J. Pharmacol.131:1025-1038(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    9. 9.
      "Role of prostanoid DP receptor variants in susceptibility to asthma."
      Oguma T. , Palmer L.J. , Birben E. , Sonna L.A. , Asano K. , Lilly C.M.
      N. Engl. J. Med.351:1752-1763(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN SUSCEPTIBILITY TO ASRT1
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