PIGR ELISA Kit for Human(Homo sapiens) | EIAab.comPIGR ELISA Kit for Human(Homo sapiens)

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Index > Protein center > PIGR(Gene name) > Human

PIGR (Gene name),

Polymeric immunoglobulin receptor (Protein name ), PIGR_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

PIGR;

Protein name:

Polymeric immunoglobulin receptor(PIgR;Poly-Ig receptor);

Alternative:

Hepatocellular carcinoma-associated protein TB6;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.

Subcellular Location:

Secretory component Secreted

Protein Attributes:

Sequence length:

764

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

764:

STVAAEAQDG | PQEA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:5284

Pfam:

PF07686

MIM:

173880

String:

P01833

STRING:

9606.ENSP00000348888

SMR:

P01833

UniGene:

Hs.497589

Uniprot:

P01833

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ELISA Kit for Human PIgR

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E1286h

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96T

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ELISA Kit for Human PIgR

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E1286b

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96T

ELISA Kit for Human PIgR

Cat.:

E1286m

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96T

ELISA Kit for Human PIgR

Cat.:

E1286r

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Packing:

96T

ELISA Kit for Human PIgR

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ELISA Kit for Human PIgR

Cat.:

E1286p

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Packing:

96T

CLIA Kit for Human PIgR

Cat.:

U1286r

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96T

CLIA Kit for Human PIgR

Cat.:

U1286b

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MSDS:

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Packing:

96T

CLIA Kit for Human PIgR

Cat.:

U1286m

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human PIgR

Cat.:

U1286p

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MSDS:

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Packing:

96T

CLIA Kit for Human PIgR

Cat.:

U1286h

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Manual:

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Packing:

96T

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CLIA Kit for Human PIgR

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Polyclonal Antibody for Human PIgR

Cat.:

P1286Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human PIgR

Cat.:

P1286Rb-r

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40ug/0.2ml

Polyclonal Antibody for Human PIgR

Cat.:

P1286Rb-m

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40ug/0.2ml

Monoclonal Antibody for Human PIgR

Protein for Human PIgR

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤3.5

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤7.1

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

Recovery was determined by spiking various levels of PIgR into serum and plasma .

Sample Type	Average(%)	Recovery Range (%)
Serum	88	79-99
Plasma	95	90-103

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of PIgR and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	85-98%	80-96%	93-101%	93-105%
EDTA plasma(n=5)	90-101%	85-94%	89-96%	87-99%
heparin plasma(n=5)	83-94%	90-102%	94-103%	92-101%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The human transmembrane secretory component (poly-Ig receptor): molecular cloning, restriction fragment length polymorphism and chromosomal sublocalization."
Krajci P. , Grzeschik K.H. , Geurts van Kessel A.H. , Olaisen B. , Brandtzaeg P.
Hum. Genet.87:642-648(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT SER-365
2.

"Molecular cloning and exon-intron mapping of the gene encoding human transmembrane secretory component (the poly-Ig receptor)."
Krajci P. , Kvale D. , Tasken K. , Brandtzaeg P.
Eur. J. Immunol.22:2309-2315(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT SER-365
3.

"Cloning and characterization of hepatocellular carcinoma associated-genes."
Dong X. , Pang X. , Cheng W.
Submitted (2002-11) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
4.

"The full-ORF clone resource of the German cDNA consortium."
Bechtel S. , Rosenfelder H. , Duda A. , Schmidt C.P. , Ernst U. , Wellenreuther R. , Mehrle A. , Schuster C. , Bahr A. , Bloecker H. , Heubner D. , Hoerlein A. , Michel G. , Wedler H. , Koehrer K. , Ottenwaelder B. , Poustka A. , Wiemann S. , more...
BMC Genomics8:399-399(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-365
tissue: Small intestine.
5.

"Molecular cloning of the human transmembrane secretory component (poly-Ig receptor) and its mRNA expression in human tissues."
Krajci P. , Solberg R. , Sandberg M. , Oyen O. , Jahnsen T. , Brandtzaeg P.
Biochem. Biophys. Res. Commun.158:783-789(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 72-764;VARIANT SER-365
6.

"The primary structure of human free secretory component and the arrangement of disulfide bonds."
Eiffert H. , Quentin E. , Decker J. , Hillemeir S. , Hufschmidt M. , Klingmueller D. , Weber M.H. , Hilschmann N.
Hoppe-Seyler's Z. Physiol. Chem.365:1489-1495(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 19-577;VARIANT SER-365;DISULFIDE BONDS;GLYCOSYLATION AT ASN-83; ASN-90; ASN-135; ASN-186; ASN-421; ASN-469 AND ASN-499
7.

"Determination of the molecular structure of the human free secretory component."
Eiffert H. , Quentin E. , Wiederhold M. , Hillemeir S. , Decker J. , Weber M. , Hilschmann N.
Biol. Chem. Hoppe-Seyler372:119-128(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 19-577;VARIANT SER-365
8.

"Human free secretory component is composed of the first 585 amino acid residues of the polymeric immunoglobulin receptor."
Hughes G.J. , Frutiger S. , Savoy L.-A. , Reason A.J. , Morris H.R. , Jaton J.-C.
FEBS Lett.410:443-446(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 118-138; 212-230; 232-268; 273-288 AND 578-603
9.

"A proteomic analysis of human bile."
Kristiansen T.Z. , Bunkenborg J. , Gronborg M. , Molina H. , Thuluvath P.J. , Argani P. , Goggins M.G. , Maitra A. , Pandey A.
Mol. Cell. Proteomics3:715-728(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-83; ASN-90; ASN-421 AND ASN-469
tissue: Bile.
10.

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-90; ASN-421 AND ASN-469
tissue: Plasma.
11.

"Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry."
Ramachandran P. , Boontheung P. , Xie Y. , Sondej M. , Wong D.T. , Loo J.A.
J. Proteome Res.5:1493-1503(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-83; ASN-90; ASN-186; ASN-421; ASN-469 AND ASN-499
tissue: Saliva.
12.

"Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry."
Picariello G. , Ferranti P. , Mamone G. , Roepstorff P. , Addeo F.
Proteomics8:3833-3847(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-83; ASN-90; ASN-135; ASN-186; ASN-421; ASN-469 AND ASN-499
tissue: Milk.
13.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-421 AND ASN-469
tissue: Liver.
14.

"A strategy for precise and large scale identification of core fucosylated glycoproteins."
Jia W. , Lu Z. , Fu Y. , Wang H.P. , Wang L.H. , Chi H. , Yuan Z.F. , Zheng Z.B. , Song L.N. , Han H.H. , Liang Y.M. , Wang J.L. , Cai Y. , Zhang Y.K. , Deng Y.L. , Ying W.T. , He S.M. , Qian X.H.
Mol. Cell. Proteomics8:913-923(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-469
15.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
16.

"Crystal structure of a polymeric immunoglobulin binding fragment of the human polymeric immunoglobulin receptor."
Hamburger A.E. , West A.P. Jr. , Bjorkman P.J.
Structure12:1925-1935(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 19-127

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