Plcg1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comPlcg1 ELISA Kit for Rat(Rattus norvegicus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Plcg1(Gene name) > Rat

Plcg1 (Gene name),

1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 (Protein name ), PLCG1_RAT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Plcg1;

Protein name:

1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1;

Alternative:

Phospholipase C-gamma-1(PLC-gamma-1);Phosphoinositide phospholipase C-gamma-1;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts (via SH2 domain) with FGFR1, FGFR2, FGFR3 and FGFR4 (phosphorylated). Interacts (via SH3 domain) with AGAP2. Interacts with LAT (phosphorylated) upon TCR activation. Interacts (via SH3 domain) with the Pro-rich domain of TNK1. Associates with BLNK, VAV1, GRB2 and NCK1 in a B-cell antigen receptor-dependent fashion. Interacts with CBLB in activated T-cells; which inhibits phosphorylation. Interacts with SHB. Interacts (via SH3 domain) with the Arg/Gly-rich-flanked Pro-rich domains of KHDRBS1/SAM68. This interaction is selectively regulated by arginine methylation of KHDRBS1/SAM68. Interacts with INPP5D/SHIP1, THEMIS and CLNK (By similarity). Interacts with RALGPS1. Interacts (via the SH2 domains) with VIL1 (phosphorylated at C-terminus tyrosine phosphorylation sites). Interacts (via SH2 domain) with RET (By similarity). Interacts with AXL and KIT.

Function:

Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand-mediated activation of receptor-type tyrosine kinases, such as fibroblast growth factor receptors. Plays a role in actin reorganization and cell migration.

Subcellular Location:

Cell projection lamellipodium Cell projection ruffle Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.

Protein Attributes:

Sequence length:

1290

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1200:

1250:

1290:

ARYQQPFEDF | RISQEHLADH | FDSRERRAPR | RTRVNGDNRL |

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

UniGene:

Rn.11243

STRING:

10116.ENSRNOP00000022276

KEGG:

rno:25738

String:

P10686

Pfam:

PF00168

SMR:

P10686

Uniprot:

P10686

FOR

ELISA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

Cat.:

E0269h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

Cat.:

E0269m

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

Please sign in first.

ELISA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

Cat.:

E0269b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

ELISA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

Cat.:

E0269r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

Cat.:

U0269b

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

Cat.:

U0269h

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

Cat.:

U0269r

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

Cat.:

U0269m

Price:

Please sign in first.

MSDS:

Please sign in first.

Packing:

96T

Polyclonal Antibody for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

Cat.:

P0269Rb-m

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

Cat.:

P0269Rb-h

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

Cat.:

P0269Rb-r

Price:

Please sign in first.

Packing:

40ug/0.2ml

Polyclonal Antibody for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

Monoclonal Antibody for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

Protein for Rat 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Inositol phospholipid-specific phospholipase C: complete cDNA and protein sequences and sequence homology to tyrosine kinase-related oncogene products."
Suh P.-G. , Ryu S.H. , Moon K.H. , Suh H.W. , Rhee S.G.
Proc. Natl. Acad. Sci. U.S.A.85:5419-5423(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Promoter region of the rat phospholipase C-gamma 1 gene."
Lee S.J. , Ryu S.H. , Suh P.G.
Biochem. Biophys. Res. Commun.194:294-300(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-29
3.

"Signal transduction by fibroblast growth factor receptor-4 (FGFR-4). Comparison with FGFR-1."
Vainikka S. , Joukov V. , Wennstrom S. , Bergman M. , Pelicci P.G. , Alitalo K.
J. Biol. Chem.269:18320-18326(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FGFR4;PHOSPHORYLATION
4.

"Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE."
Ye K. , Aghdasi B. , Luo H.R. , Moriarity J.L. , Wu F.Y. , Hong J.J. , Hurt K.J. , Bae S.S. , Suh P.-G. , Snyder S.H.
Nature415:541-544(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AGAP2;MUTAGENESIS OF PRO-842
5.

"Structural characterization of the split pleckstrin homology domain in phospholipase C-gamma1 and its interaction with TRPC3."
Wen W. , Yan J. , Zhang M.
J. Biol. Chem.281:12060-12068(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 489-553 AND 663-759

Product Feedback Wall

* Email:
*Comments: