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Index > Protein center > PLEC(Gene name) > Human
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  • PLEC (Gene name),
  • Plectin (Protein name ),  PLEC_HUMAN from NCBI database.
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  • Gene name:
    PLEC(PLEC1);
    Protein name:
    Plectin(PCN;PLTN);
    Alternative:
    Plectin-1;Hemidesmosomal protein 1(HD1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer or homotetramer. Interacts (via actin-binding domain) with Nesprin-3. Interacts (via CH 1 domain) with VIM (via rod region) (By similarity). Interacts with COL17A1 (via N-terminus). Interacts (via N-terminus) with DST isoform 1 (via N-terminus).
    Function:
    Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintainance of myofibers integrity.
    Subcellular Location:
    Cytoplasm cytoskeleton Cell junction hemidesmosome
    Protein Attributes:
    Sequence length:
    4684
    Sequence:
    50:
    MVAGMLMPRD | QLRAIYEVLF | REGVMVAKKD | RRPRSLHPHV | PGVTNLQVMR | 
    100:
    AMASLRARGL | VRETFAWCHF | YWYLTNEGIA | HLRQYLHLPP | EIVPASLQRV | 
    150:
    RRPVAMVMPA | RRTPHVQAVQ | GPLGSPPKRG | PLPTEEQRVY | RRKELEEVSP | 
    200:
    ETPVVPATTQ | RTLARPGPEP | APATDERDRV | QKKTFTKWVN | KHLIKAQRHI | 
    250:
    SDLYEDLRDG | HNLISLLEVL | SGDSLPREKG | RMRFHKLQNV | QIALDYLRHR | 
    300:
    QVKLVNIRND | DIADGNPKLT | LGLIWTIILH | FQISDIQVSG | QSEDMTAKEK | 
    350:
    LLLWSQRMVE | GYQGLRCDNF | TSSWRDGRLF | NAIIHRHKPL | LIDMNKVYRQ | 
    400:
    TNLENLDQAF | SVAERDLGVT | RLLDPEDVDV | PQPDEKSIIT | YVSSLYDAMP | 
    450:
    RVPDVQDGVR | ANELQLRWQE | YRELVLLLLQ | WMRHHTAAFE | ERRFPSSFEE | 
    500:
    IEILWSQFLK | FKEMELPAKE | ADKNRSKGIY | QSLEGAVQAG | QLKVPPGYHP | 
    550:
    LDVEKEWGKL | HVAILEREKQ | LRSEFERLEC | LQRIVTKLQM | EAGLCEEQLN | 
    600:
    QADALLQSDV | RLLAAGKVPQ | RAGEVERDLD | KADSMIRLLF | NDVQTLKDGR | 
    650:
    HPQGEQMYRR | VYRLHERLVA | IRTEYNLRLK | AGVAAPATQV | AQVTLQSVQR | 
    700:
    RPELEDSTLR | YLQDLLAWVE | ENQHRVDGAE | WGVDLPSVEA | QLGSHRGLHQ | 
    750:
    SIEEFRAKIE | RARSDEGQLS | PATRGAYRDC | LGRLDLQYAK | LLNSSKARLR | 
    800:
    SLESLHSFVA | AATKELMWLN | EKEEEEVGFD | WSDRNTNMTA | KKESYSALMR | 
    850:
    ELELKEKKIK | ELQNAGDRLL | REDHPARPTV | ESFQAALQTQ | WSWMLQLCCC | 
    900:
    IEAHLKENAA | YFQFFSDVRE | AEGQLQKLQE | ALRRKYSCDR | SATVTRLEDL | 
    950:
    LQDAQDEKEQ | LNEYKGHLSG | LAKRAKAVVQ | LKPRHPAHPM | RGRLPLLAVC | 
    1000:
    DYKQVEVTVH | KGDECQLVGP | AQPSHWKVLS | SSGSEAAVPS | VCFLVPPPNQ | 
    1050:
    EAQEAVTRLE | AQHQALVTLW | HQLHVDMKSL | LAWQSLRRDV | QLIRSWSLAT | 
    1100:
    FRTLKPEEQR | QALHSLELHY | QAFLRDSQDA | GGFGPEDRLM | AEREYGSCSH | 
    1150:
    HYQQLLQSLE | QGAQEESRCQ | RCISELKDIR | LQLEACETRT | VHRLRLPLDK | 
    1200:
    EPARECAQRI | AEQQKAQAEV | EGLGKGVARL | SAEAEKVLAL | PEPSPAAPTL | 
    1250:
    RSELELTLGK | LEQVRSLSAI | YLEKLKTISL | VIRGTQGAEE | VLRAHEEQLK | 
    1300:
    EAQAVPATLP | ELEATKASLK | KLRAQAEAQQ | PTFDALRDEL | RGAQEVGERL | 
    1350:
    QQRHGERDVE | VERWRERVAQ | LLERWQAVLA | QTDVRQRELE | QLGRQLRYYR | 
    1400:
    ESADPLGAWL | QDARRRQEQI | QAMPLADSQA | VREQLRQEQA | LLEEIERHGE | 
    1450:
    KVEECQRFAK | QYINAIKDYE | LQLVTYKAQL | EPVASPAKKP | KVQSGSESVI | 
    1500:
    QEYVDLRTHY | SELTTLTSQY | IKFISETLRR | MEEEERLAEQ | QRAEERERLA | 
    1550:
    EVEAALEKQR | QLAEAHAQAK | AQAEREAKEL | QQRMQEEVVR | REEAAVDAQQ | 
    1600:
    QKRSIQEELQ | QLRQSSEAEI | QAKARQAEAA | ERSRLRIEEE | IRVVRLQLEA | 
    1650:
    TERQRGGAEG | ELQALRARAE | EAEAQKRQAQ | EEAERLRRQV | QDESQRKRQA | 
    1700:
    EVELASRVKA | EAEAAREKQR | ALQALEELRL | QAEEAERRLR | QAEVERARQV | 
    1750:
    QVALETAQRS | AEAELQSKRA | SFAEKTAQLE | RSLQEEHVAV | AQLREEAERR | 
    1800:
    AQQQAEAERA | REEAERELER | WQLKANEALR | LRLQAEEVAQ | QKSLAQAEAE | 
    1850:
    KQKEEAEREA | RRRGKAEEQA | VRQRELAEQE | LEKQRQLAEG | TAQQRLAAEQ | 
    1900:
    ELIRLRAETE | QGEQQRQLLE | EELARLQREA | AAATQKRQEL | EAELAKVRAE | 
    1950:
    MEVLLASKAR | AEEESRSTSE | KSKQRLEAEA | GRFRELAEEA | ARLRALAEEA | 
    2000:
    KRQRQLAEED | AARQRAEAER | VLAEKLAAIG | EATRLKTEAE | IALKEKEAEN | 
    2050:
    ERLRRLAEDE | AFQRRRLEEQ | AAQHKADIEE | RLAQLRKASD | SELERQKGLV | 
    2100:
    EDTLRQRRQV | EEEILALKAS | FEKAAAGKAE | LELELGRIRS | NAEDTLRSKE | 
    2150:
    QAELEAARQR | QLAAEEERRR | REAEERVQKS | LAAEEEAARQ | RKAALEEVER | 
    2200:
    LKAKVEEARR | LRERAEQESA | RQLQLAQEAA | QKRLQAEEKA | HAFAVQQKEQ | 
    2250:
    ELQQTLQQEQ | SVLDQLRGEA | EAARRAAEEA | EEARVQAERE | AAQSRRQVEE | 
    2300:
    AERLKQSAEE | QAQARAQAQA | AAEKLRKEAE | QEAARRAQAE | QAALRQKQAA | 
    2350:
    DAEMEKHKKF | AEQTLRQKAQ | VEQELTTLRL | QLEETDHQKN | LLDEELQRLK | 
    2400:
    AEATEAARQR | SQVEEELFSV | RVQMEELSKL | KARIEAENRA | LILRDKDNTQ | 
    2450:
    RFLQEEAEKM | KQVAEEAARL | SVAAQEAARL | RQLAEEDLAQ | QRALAEKMLK | 
    2500:
    EKMQAVQEAT | RLKAEAELLQ | QQKELAQEQA | RRLQEDKEQM | AQQLAEETQG | 
    2550:
    FQRTLEAERQ | RQLEMSAEAE | RLKLRVAEMS | RAQARAEEDA | QRFRKQAEEI | 
    2600:
    GEKLHRTELA | TQEKVTLVQT | LEIQRQQSDH | DAERLREAIA | ELEREKEKLQ | 
    2650:
    QEAKLLQLKS | EEMQTVQQEQ | LLQETQALQQ | SFLSEKDSLL | QRERFIEQEK | 
    2700:
    AKLEQLFQDE | VAKAQQLREE | QQRQQQQMEQ | ERQRLVASME | EARRRQHEAE | 
    2750:
    EGVRRKQEEL | QQLEQQRRQQ | EELLAEENQR | LREQLQLLEE | QHRAALAHSE | 
    2800:
    EVTASQVAAT | KTLPNGRDAL | DGPAAEAEPE | HSFDGLRRKV | SAQRLQEAGI | 
    2850:
    LSAEELQRLA | QGHTTVDELA | RREDVRHYLQ | GRSSIAGLLL | KATNEKLSVY | 
    2900:
    AALQRQLLSP | GTALILLEAQ | AASGFLLDPV | RNRRLTVNEA | VKEGVVGPEL | 
    2950:
    HHKLLSAERA | VTGYKDPYTG | QQISLFQAMQ | KGLIVREHGI | RLLEAQIATG | 
    3000:
    GVIDPVHSHR | VPVDVAYRRG | YFDEEMNRVL | ADPSDDTKGF | FDPNTHENLT | 
    3050:
    YLQLLERCVE | DPETGLCLLP | LTDKAAKGGE | LVYTDSEARD | VFEKATVSAP | 
    3100:
    FGKFQGKTVT | IWEIINSEYF | TAEQRRDLLR | QFRTGRITVE | KIIKIIITVV | 
    3150:
    EEQEQKGRLC | FEGLRSLVPA | AELLESRVID | RELYQQLQRG | ERSVRDVAEV | 
    3200:
    DTVRRALRGA | NVIAGVWLEE | AGQKLSIYNA | LKKDLLPSDM | AVALLEAQAG | 
    3250:
    TGHIIDPATS | ARLTVDEAVR | AGLVGPEFHE | KLLSAEKAVT | GYRDPYTGQS | 
    3300:
    VSLFQALKKG | LIPREQGLRL | LDAQLSTGGI | VDPSKSHRVP | LDVACARGCL | 
    3350:
    DEETSRALSA | PRADAKAYSD | PSTGEPATYG | ELQQRCRPDQ | LTGLSLLPLS | 
    3400:
    EKAARARQEE | LYSELQARET | FEKTPVEVPV | GGFKGRTVTV | WELISSEYFT | 
    3450:
    AEQRQELLRQ | FRTGKVTVEK | VIKILITIVE | EVETLRQERL | SFSGLRAPVP | 
    3500:
    ASELLASGVL | SRAQFEQLKD | GKTTVKDLSE | LGSVRTLLQG | SGCLAGIYLE | 
    3550:
    DTKEKVSIYE | AMRRGLLRAT | TAALLLEAQA | ATGFLVDPVR | NQRLYVHEAV | 
    3600:
    KAGVVGPELH | EQLLSAEKAV | TGYRDPYSGS | TISLFQAMQK | GLVLRQHGIR | 
    3650:
    LLEAQIATGG | IIDPVHSHRV | PVDVAYQRGY | FSEEMNRVLA | DPSDDTKGFF | 
    3700:
    DPNTHENLTY | RQLLERCVED | PETGLRLLPL | KGAEKAEVVE | TTQVYTEEET | 
    3750:
    RRAFEETQID | IPGGGSHGGS | TMSLWEVMQS | DLIPEEQRAQ | LMADFQAGRV | 
    3800:
    TKERMIIIII | EIIEKTEIIR | QQGLASYDYV | RRRLTAEDLF | EARIISLETY | 
    3850:
    NLLREGTRSL | REALEAESAW | CYLYGTGSVA | GVYLPGSRQT | LSIYQALKKG | 
    3900:
    LLSAEVARLL | LEAQAATGFL | LDPVKGERLT | VDEAVRKGLV | GPELHDRLLS | 
    3950:
    AERAVTGYRD | PYTEQTISLF | QAMKKELIPT | EEALRLLDAQ | LATGGIVDPR | 
    4000:
    LGFHLPLEVA | YQRGYLNKDT | HDQLSEPSEV | RSYVDPSTDE | RLSYTQLLRR | 
    4050:
    CRRDDGTGQL | LLPLSDARKL | TFRGLRKQIT | MEELVRSQVM | DEATALQLRE | 
    4100:
    GLTSIEEVTK | NLQKFLEGTS | CIAGVFVDAT | KERLSVYQAM | KKGIIRPGTA | 
    4150:
    FELLEAQAAT | GYVIDPIKGL | KLTVEEAVRM | GIVGPEFKDK | LLSAERAVTG | 
    4200:
    YKDPYSGKLI | SLFQAMKKGL | ILKDHGIRLL | EAQIATGGII | DPEESHRLPV | 
    4250:
    EVAYKRGLFD | EEMNEILTDP | SDDTKGFFDP | NTEENLTYLQ | LMERCITDPQ | 
    4300:
    TGLCLLPLKE | KKRERKTSSK | SSVRKRRVVI | VDPETGKEMS | VYEAYRKGLI | 
    4350:
    DHQTYLELSE | QECEWEEITI | SSSDGVVKSM | IIDRRSGRQY | DIDDAIAKNL | 
    4400:
    IDRSALDQYR | AGTLSITEFA | DMLSGNAGGF | RSRSSSVGSS | SSYPISPAVS | 
    4450:
    RTQLASWSDP | TEETGPVAGI | LDTETLEKVS | ITEAMHRNLV | DNITGQRLLE | 
    4500:
    AQACTGGIID | PSTGERFPVT | DAVNKGLVDK | IMVDRINLAQ | KAFCGFEDPR | 
    4550:
    TKTKMSAAQA | LKKGWLYYEA | GQRFLEVQYL | TGGLIEPDTP | GRVPLDEALQ | 
    4600:
    RGTVDARTAQ | KLRDVGAYSK | YLTCPKTKLK | ISYKDALDRS | MVEEGTGLRL | 
    4650:
    LEAAAQSTKG | YYSPYSVSGS | GSTAGSRTGS | RTGSRAGSRR | GSFDATGSGF | 
    4684:
    SMTFSSSSYS | SSGYGRRYAS | GSSASLGGPE | SAVA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    UniGene:
    MIM:
    Pfam:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human PCN
    Cat.:
    E15105h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human PCN
    MSDS:
    Please sign in first.
    ELISA Kit for Human PCN
    Cat.:
    E15105m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human PCN
    MSDS:
    Please sign in first.
    CLIA Kit for Human PCN
    MSDS:
    Please sign in first.
    CLIA Kit for Human PCN
    Cat.:
    U15105h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human PCN
    Polyclonal Antibody for Human PCN
    Polyclonal Antibody for Human PCN
    Monoclonal Antibody for Human PCN
    Monoclonal Antibody for Human PCN
    Monoclonal Antibody for Human PCN
    Protein for Human PCN
    Protein for Human PCN
    Protein for Human PCN

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Human plectin: organization of the gene, sequence analysis, and chromosome localization (8q24)."
      Liu C.-G. , Maercker C. , Castanon M.J. , Hauptmann R. , Wiche G.
      Proc. Natl. Acad. Sci. U.S.A.93:4278-4283(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Placenta.
    2. 2.
      "Loss of plectin causes epidermolysis bullosa with muscular dystrophy: cDNA cloning and genomic organization."
      McLean W.H.I. , Pulkkinen L. , Smith F.J.D. , Rugg E.L. , Lane E.B. , Bullrich F. , Burgeson R.E. , Amano S. , Hudson D.L. , Owaribe K. , McGrath J.A. , McMillan J.R. , Eady R.A.J. , Leigh I.M. , Christiano A.M. , Uitto J.
      Genes Dev.10:1724-1735(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 2 AND 3);DISEASE;VARIANT VAL-1321
    3. 3.
      "Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation."
      Zhang T. , Haws P. , Wu Q.
      Genome Res.14:79-89(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 4; 5; 6; 7; 8 AND 9)
    4. 5.
      Bienvenut W.V. , Lilla S. , von Kriegsheim A. , Lempens A. , Kolch W.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 14-21; 209-227; 237-248; 301-316; 329-336; 350-365; 372-417; 510-517; 588-597; 631-675; 697-706; 714-724; 734-740; 751-764; 857-869; 897-908; 927-934; 1029-1037; 1045-1052; 1076-1088; 1131-1139; 1166-1175; 1187-1210; 1216-1224; 1227-1243; 1251-1266; 1274-1291; 1318-1335; 1338-1344; 1351-1364; 1366-1382; 1411-1438; 1473-1479; 1499-1508; 1554-1563; 1596-1603; 1606-1616; 1628-1638; 1649-1657; 1671-1679; 1699-1709; 1732-1744; 1783-1792; 1825-1833; 1846-1854; 1867-1875; 1888-1908; 1976-1994; 2006-2014; 2048-2055; 2058-2068; 2079-2087; 2098-2108; 2130-2139; 2142-2150; 2172-2182; 2199-2217; 2310-2316; 2319-2329; 2340-2348; 2361-2379; 2402-2409; 2420-2429; 2432-2442; 2462-2473; 2483-2503; 2512-2521; 2565-2575; 2587-2594; 2651-2663; 2685-2693; 2705-2761; 2768-2787; 2795-2821; 2833-2841; 2847-2881; 2885-2903; 2942-2968; 2979-3007; 3028-3039; 3045-3053; 3095-3106; 3109-3127; 3132-3139; 3146-3154; 3175-3183; 3213-3231; 3244-3259; 3270-3285; 3289-3297; 3317-3335; 3356-3368; 3374-3384; 3424-3436; 3447-3469; 3477-3485; 3506-3513; 3519-3540; 3544-3568; 3601-3637; 3648-3661; 3667-3676; 3686-3702; 3739-3749; 3771-3781; 3784-3804; 3839-3878; 3887-3897; 3926-3963; 3969-3999; 4004-4018; 4027-4060; 4084-4091; 4122-4138; 4159-4167; 4179-4205; 4278-4296; 4339-4348; 4354-4360; 4384-4401; 4429-4447; 4467-4475; 4492-4500; 4543-4551; 4590-4627 AND 4668-4684;PHOSPHORYLATION AT SER-4385;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Ovarian carcinoma.
    5. 6.
      "Analysis of the interactions between BP180, BP230, plectin and the integrin alpha6beta4 important for hemidesmosome assembly."
      Koster J. , Geerts D. , Favre B. , Borradori L. , Sonnenberg A.
      J. Cell Sci.116:387-399(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH COL17A1;SUBCELLULAR LOCATION
    6. 7.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-125; SER-149; SER-720; SER-1435; SER-1721; THR-4030 AND THR-4411;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 8.
      "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
      Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
      Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic kidney.
    8. 9.
      "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T. , Yi W. , Lu B. , Park S.K. , Xu T. , Lee J.-D. , Yates J.R. III
      J. Proteome Res.7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 10.
      "Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment."
      Carrascal M. , Ovelleiro D. , Casas V. , Gay M. , Abian J.
      J. Proteome Res.7:5167-5176(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: T-cell.
    10. 11.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1435;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-125; SER-149; SER-720; SER-4382; SER-4385; SER-4386; SER-4389; SER-4390; SER-4391; SER-4392; SER-4396; SER-4613; SER-4622; SER-4626 AND SER-4642;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-42 (ISOFORMS 2 AND 3);PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-21 (ISOFORM 4);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 13.
      "TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton."
      Nery F.C. , Zeng J. , Niland B.P. , Hewett J. , Farley J. , Irimia D. , Li Y. , Wiche G. , Sonnenberg A. , Breakefield X.O.
      J. Cell Sci.121:3476-3486(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TOR1A
    13. 14.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 15.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-720; THR-4030 AND SER-4626;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 16.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-4386; SER-4389; SER-4396; SER-4613; SER-4618 AND SER-4626;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-42 (ISOFORMS 2 AND 3);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    16. 17.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-3091 AND LYS-3420;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    17. 18.
      "Mutation in exon 1f of PLEC, leading to disruption of plectin isoform 1f, causes autosomal-recessive limb-girdle muscular dystrophy."
      Gundesli H. , Talim B. , Korkusuz P. , Balci-Hayta B. , Cirak S. , Akarsu N.A. , Topaloglu H. , Dincer P.
      Am. J. Hum. Genet.87:834-841(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF ISOFORM 9;INVOLVEMENT IN LGMD2Q
    18. 19.
      "BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin."
      Steiner-Champliaud M.F. , Schneider Y. , Favre B. , Paulhe F. , Praetzel-Wunder S. , Faulkner G. , Konieczny P. , Raith M. , Wiche G. , Adebola A. , Liem R.K. , Langbein L. , Sonnenberg A. , Fontao L. , Borradori L.
      Exp. Cell Res.316:297-313(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DST
    19. 20.
      "Plectin deficiency leads to both muscular dystrophy and pyloric atresia in epidermolysis bullosa simplex."
      Natsuga K. , Nishie W. , Shinkuma S. , Arita K. , Nakamura H. , Ohyama M. , Osaka H. , Kambara T. , Hirako Y. , Shimizu H.
      Hum. Mutat.31:E1687-E1698(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN MD-EBS AND EBS-PA
    20. 21.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-113; SER-125; SER-149; SER-720; SER-1435; SER-1732; THR-4030; SER-4382; SER-4396; SER-4400; SER-4613; SER-4622 AND SER-4642;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-42 (ISOFORMS 2 AND 3);PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-20 AND SER-21 (ISOFORM 4);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    21. 22.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    22. 23.
      "Novel interactions of ankyrins-G at the costameres: the muscle-specific Obscurin/Titin-Binding-related Domain (OTBD) binds plectin and filamin C."
      Maiweilidan Y. , Klauza I. , Kordeli E.
      Exp. Cell Res.317:724-736(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ANK3
    23. 24.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1435 AND THR-4030;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    24. 25.
      "The structure of a tandem pair of spectrin repeats of plectin reveals a modular organization of the plakin domain."
      Sonnenberg A. , Rojas A.M. , de Pereda J.M.
      J. Mol. Biol.368:1379-1391(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS) OF 409-640
    25. 26.
      "Structural and functional analysis of the actin binding domain of plectin suggests alternative mechanisms for binding to F-actin and integrin beta4."
      Garcia-Alvarez B. , Bobkov A. , Sonnenberg A. , de Pereda J.M.
      Structure11:615-625(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.15 ANGSTROMS) OF 159-403
    26. 27.
      "Homozygous deletion mutations in the plectin gene (PLEC1) in patients with epidermolysis bullosa simplex associated with late-onset muscular dystrophy."
      Pulkkinen L. , Smith F.J.D. , Shimizu H. , Murata S. , Yaoita H. , Hachisuka H. , Nishikawa T. , McLean W.H.I. , Uitto J.
      Hum. Mol. Genet.5:1539-1546(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MD-EBS 1003-GLN--ALA-1005 DEL
    27. 28.
      "A compound heterozygous one amino-acid insertion/nonsense mutation in the plectin gene causes epidermolysis bullosa simplex with plectin deficiency."
      Bauer J.W. , Rouan F. , Kofler B. , Rezniczek G.A. , Kornacker I. , Muss W. , Hametner R. , Klausegger A. , Huber A. , Pohla-Gubo G. , Wiche G. , Uitto J. , Hintner H.
      Am. J. Pathol.158:617-625(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MD-EBS LEU-429 INS
    28. 29.
      "A site-specific plectin mutation causes dominant epidermolysis bullosa simplex Ogna: two identical de novo mutations."
      Koss-Harnes D. , Hoeyheim B. , Anton-Lamprecht I. , Gjesti A. , Joergensen R.S. , Jahnsen F.L. , Olaisen B. , Wiche G. , Gedde-Dahl T. Jr.
      J. Invest. Dermatol.118:87-93(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT O-EBS TRP-2110
    29. 30.
      "Identification of a lethal form of epidermolysis bullosa simplex associated with a homozygous genetic mutation in plectin."
      Charlesworth A. , Gagnoux-Palacios L. , Bonduelle M. , Ortonne J.-P. , De Raeve L. , Meneguzzi G.
      J. Invest. Dermatol.121:1344-1348(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN EBS-PA
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