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Index > Protein center > Ube2a(Gene name) > Mouse
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  • Ube2a (Gene name),
  • Ubiquitin-conjugating enzyme E2 A (Protein name ),  UBE2A_MOUSE from NCBI database.
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  • General Annotation
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  • Gene name:
    Ube2a(Rad6a);
    Protein name:
    Ubiquitin-conjugating enzyme E2 A;
    Alternative:
    Ubiquitin carrier protein A;RAD6 homolog A(HR6A;mHR6A);Ubiquitin-protein ligase A;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with RAD18 and WAC.
    Function:
    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    152
    Sequence:
    50:
    MSTPARRRLM | RDFKRLQEDP | PAGVSGAPSE | NNIMVWNAVI | FGPEGTPFED | 
    100:
    GTFKLTIEFT | EEYPNKPPTV | RFVSKMFHPN | VYADGSICLD | ILQNRWSPTY | 
    150:
    DVSSILTSIQ | SLLDEPNPNS | PANSQAAQLY | QENKREYEKR | VSAIVEQSWR | 
    152:
    DC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    UniGene:
    KEGG:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Ubiquitin-conjugating enzyme E2 A
    Cat.:
    E0991h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse Ubiquitin-conjugating enzyme E2 A
    Cat.:
    E0991m
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    MSDS:
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    Packing:
    96T
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    CLIA Kit for Mouse Ubiquitin-conjugating enzyme E2 A
    Cat.:
    U0991h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Mouse Ubiquitin-conjugating enzyme E2 A
    Cat.:
    U0991m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Ubiquitin-conjugating enzyme E2 A
    Cat.:
    P0991Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Ubiquitin-conjugating enzyme E2 A
    Cat.:
    P0991Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Ubiquitin-conjugating enzyme E2 A
    Monoclonal Antibody for Mouse Ubiquitin-conjugating enzyme E2 A
    Protein for Mouse Ubiquitin-conjugating enzyme E2 A
    Protein for Mouse Ubiquitin-conjugating enzyme E2 A

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation of mHR6A, a gene highly homologous to the male fertility gene mHR6B."
      Roest H.P. , van Klaveren J. , Koken M.H.M. , Vermey M. , van Cappellen W.A. , Baarends W.M. , Hoogerbrugge J.W. , Bootsma D. , Hoeijmakers J.H.J. , Grootegoed J.A. , de Wit J.
      Submitted (1998-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BCBA.
      tissue: Brain.
    2. 2.
      Kwon Y.T. , Varshavsky A.
      Submitted (2001-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6.
      tissue: Skeletal muscle.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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