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Index > Protein center > Recql5(Gene name) > Mouse
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  • Recql5 (Gene name),
  • ATP-dependent DNA helicase Q5 (Protein name ),  RECQ5_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Recql5;
    Protein name:
    ATP-dependent DNA helicase Q5;
    Alternative:
    RECQL5beta;DNA helicase, RecQ-like type 5(RecQ5);RecQ protein-like 5;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Monomer. Interacts with TOP2A, TOP3A and TOP3B. Interacts with RNA polymerase II subunit POLR2A. Identified in a complex with the RNA polymerase II core bound to DNA. Interacts with RAD51.
    Function:
    DNA helicase that plays an important role in DNA replication, transcription and repair. Inhibits elongation of stalled transcripts at DNA damage sites by binding to the RNA polymerase II subunit POLR2A and blocking the TCEA1 binding site. Required for mitotic chromosome separation after cross-over events and cell cycle progress. Required for efficient DNA repair, including repair of inter-strand cross-links. Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination.
    Subcellular Location:
    Nucleus Nucleoplasm Recruited to sites of DNA damage, such as single-strand breaks and inter-strand cross-links, and at stalled replication forks.
    Protein Attributes:
    Sequence length:
    982
    Sequence:
    50:
    MSARPFSTPF | DRERRVRSTL | KKVFGFDSFK | TPLQESATMA | VVKGAEDVFV | 
    100:
    CMPTGAGKSL | CYQLPALLAS | GITIVVSPLI | ALIQDQVDHL | LALKVQVSSL | 
    150:
    NSKLSVQERK | ELLSDLERDK | PRTKLLYITP | EMAASASFQP | TLNSLVSRNL | 
    200:
    LSYLVVDEAH | CVSQWGHDFR | PDYLRLGALR | SRLAHAPCVA | LTATATPQVQ | 
    250:
    EDVFAALHLK | QPVASFKTPC | FRANLFYDVQ | FKELIPDVYG | NLRDFCLKAL | 
    300:
    GQKAENGSSS | GCGIVYCRTR | EACEQLAIEL | SSRGVNAKAY | HAGLKASDRT | 
    350:
    QVQNEWMEEK | VPVIVATISF | GMGVDKANVR | FVAHWNIAKS | MAGYYQESGR | 
    400:
    AGRDGKPSWC | RLYYSRNDRD | QVSFLIRKEL | AKLQEKRGNK | PSDKATLLAF | 
    450:
    DALVTFCEEV | GCRHAAIAKY | FGDAPPACAK | GCDYCQNPAA | ITKKLDALER | 
    500:
    SSSWSKTCIG | PSQGNGFDPE | LYEGGRRGYG | GFSRYDEGSG | GSGDEGRDEA | 
    550:
    HKREWNLFYQ | KQMSLRKGKE | PKIEEFTPPD | EDCPLREASS | RKIPKLTVKA | 
    600:
    REHCLRLLEE | ALISNHQAAG | STHGADLQAK | AVELEHETFR | NAKMVNLYKA | 
    650:
    SVLKKVAEIH | KASKDGQLYD | MESGTKSCGA | AAEFSEPSDY | DIPPTSHVYS | 
    700:
    LKPKRVGAGF | SKGPCSFQTA | TELLGKSHSQ | KQAPEAMLEG | GQEPPGWVCD | 
    750:
    LQDEDRSKPH | PGYQEKALGS | SVNCGDPSPE | KKTKGSSQGS | AKARASKKQQ | 
    800:
    LLATAARKDS | QNITRFLCQR | TESPPLPASV | PRSEDASPSC | GDVPGKCTQE | 
    850:
    VGAQGHLVAV | FQTEGPRERP | STCSLRDQSF | PEGQPSPLKE | TQAEKRPRPQ | 
    900:
    QGNPERRAQK | RLRPSTKSSI | LAEAKDSTLA | SDRSTENKVA | QEPCQLSASG | 
    950:
    TSLREAADIV | VRHLTPFYKE | GRFISKDLFK | GFARHLSHLL | AQQLSPGRSV | 
    982:
    KEEAQSLIKQ | FFHNRARCES | EADWHSLRGP | QR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse ATP-dependent DNA helicase Q5
    ELISA Kit for Mouse ATP-dependent DNA helicase Q5
    ELISA Kit for Mouse ATP-dependent DNA helicase Q5
    CLIA Kit for Mouse ATP-dependent DNA helicase Q5
    CLIA Kit for Mouse ATP-dependent DNA helicase Q5
    CLIA Kit for Mouse ATP-dependent DNA helicase Q5
    Polyclonal Antibody for Mouse ATP-dependent DNA helicase Q5
    Polyclonal Antibody for Mouse ATP-dependent DNA helicase Q5
    Polyclonal Antibody for Mouse ATP-dependent DNA helicase Q5
    Monoclonal Antibody for Mouse ATP-dependent DNA helicase Q5
    Monoclonal Antibody for Mouse ATP-dependent DNA helicase Q5
    Monoclonal Antibody for Mouse ATP-dependent DNA helicase Q5
    Protein for Mouse ATP-dependent DNA helicase Q5
    Protein for Mouse ATP-dependent DNA helicase Q5
    Protein for Mouse ATP-dependent DNA helicase Q5

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning, genomic structure and chromosomal localization of the gene encoding mouse DNA helicase RECQL5beta."
      Ohhata T. , Araki R. , Fukumura R. , Kuroiwa A. , Matsuda Y. , Abe M.
      Gene280:59-66(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 412-982
      tissue: Fibroblast.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 234-982
      strain: C57BL/6J.
      tissue: Embryo.
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