REN ELISA Kit for Human(Homo sapiens) | EIAab.comREN ELISA Kit for Human(Homo sapiens)

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Index > Protein center > REN(Gene name) > Human

REN (Gene name),

Renin (Protein name ), RENI_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

REN;

Protein name:

Renin;

Alternative:

Angiotensinogenase;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with ATP6AP2.

Function:

Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.

Subcellular Location:

Secreted Membrane Associated to membranes via binding to ATP6AP2.

Protein Attributes:

Sequence length:

406

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

406:

GFALAR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

179820

Pfam:

PF07966

KEGG:

hsa:5972

String:

P00797

UniGene:

Hs.3210

SMR:

P00797

STRING:

9606.ENSP00000272190

Uniprot:

P00797

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ELISA Kit for Human Renin

Cat.:

E0889h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human Renin

Cat.:

E0889d

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Renin

Cat.:

U0889h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human Renin

Cat.:

U0889d

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Renin

Cat.:

P0889Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Renin

Protein for Human Renin

Cat.:

R0889h

Price:

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Packing:

1mg

Purity:

>90%

Protein for Human Renin

R&D Technical Data

12% SDS-PAGE analysis

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Cloning and sequence analysis of cDNA for human renin precursor."
Imai T. , Miyazaki H. , Hirose S. , Hori H. , Hayashi T. , Kageyama R. , Ohkubo H. , Nakanishi S. , Murakami K.
Proc. Natl. Acad. Sci. U.S.A.80:7405-7409(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1)
2.

"New possibilities for intracellular renin and inactive renin now that the structure of the human renin gene has been elucidated."
Morris B.J.
Clin. Sci.71:345-355(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 2)
3.

"Primary structure of the human renin gene."
Hardman J.A. , Hort Y.J. , Catanzaro D.F. , Tellam J.T. , Baxter J.D. , Morris B.J. , Shine J.
DNA3:457-468(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Fetal liver.
4.

Rieder M.J. , da Ponte S.H. , Kuldanek S.A. , Rajkumar N. , Smith J.D. , Toth E.J. , Krauss R.M. , Nickerson D.A.
Submitted (2003-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.

"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
6.

NIEHS SNPs program
Submitted (2007-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
7.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Colon.
tissue: Ovary.
9.

"Molecular cloning and nucleotide sequence of a human renin cDNA fragment."
Soubrier F. , Panthier J.-J. , Corvol P. , Rougeon F.
Nucleic Acids Res.11:7181-7190(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 108-406 (ISOFORM 1)
10.

"Human renin gene of renin-secreting tumor."
Fukamizu A. , Nishi K. , Nishimatsu S. , Miyazaki H. , Hirose S. , Murakami K.
Gene49:139-145(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-33
11.

"Identification of negative and positive regulatory elements in the human renin gene."
Burt D.W. , Nakamura N. , Kelley P. , Dzau V.J.
J. Biol. Chem.264:7357-7362(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-33
12.

"Segmental homology between the promoter region of the human renin gene and the mouse ren1 and ren2 promoter regions."
Soubrier F. , Panthier J.J. , Houot A.-M. , Rougeon F. , Corvol P.
Gene41:85-92(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-33
13.

"Isolation and characterization of recombinant human prorenin in Chinese hamster ovary cells."
Ishizuka Y. , Shoda A. , Yoshida S. , Kawamura Y. , Haraguchi K. , Murakami K.
J. Biochem.109:30-35(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 24-42 AND 67-86
14.

"Pivotal role of the renin/prorenin receptor in angiotensin II production and cellular responses to renin."
Nguyen G. , Delarue F. , Burckle C. , Bouzhir L. , Giller T. , Sraer J.-D.
J. Clin. Invest.109:1417-1427(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATP6AP2;CHARACTERIZATION
15.

"Structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5-A resolution."
Sielecki A.R. , Hayakawa K. , Fujinaga M. , Murphy M.E.P. , Fraser M. , Muir A.K. , Carilli C.T. , Lewicki J.A. , Baxter J.D. , James M.N.G.
Science243:1346-1351(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS)
16.

"X-ray analyses of peptide-inhibitor complexes define the structural basis of specificity for human and mouse renins."
Dhanaraj V. , Dealwis C.G. , Frazao C. , Badasso M. , Sibanda B.L. , Tickle I.J. , Cooper J.B. , Driessen H.P.C. , Newman M. , Aguilar C. , Wood S.P. , Blundell T.L. , Hobart P.M. , Geoghegan K.F. , Ammirati M.J. , Danley D.E. , O'Connor B.A. , Hoover D.J.
Nature357:466-472(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS)
17.

"A redox switch in angiotensinogen modulates angiotensin release."
Zhou A. , Carrell R.W. , Murphy M.P. , Wei Z. , Yan Y. , Stanley P.L. , Stein P.E. , Broughton Pipkin F. , Read R.J.
Nature468:108-111(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (4.33 ANGSTROMS) OF 24-406 OF MUTANT ALA-292 IN COMPLEX WITH ANGIOTENSINOGEN;DISULFIDE BONDS
18.

"Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis."
Gribouval O. , Gonzales M. , Neuhaus T. , Aziza J. , Bieth E. , Laurent N. , Bouton J.M. , Feuillet F. , Makni S. , Ben Amar H. , Laube G. , Delezoide A.-L. , Bouvier R. , Dijoud F. , Ollagnon-Roman E. , Roume J. , Joubert M. , Antignac C. , more...
Nat. Genet.37:964-968(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS RTD ASN-104 AND LYS-230
19.

"Dominant renin gene mutations associated with early-onset hyperuricemia, anemia, and chronic kidney failure."
Zivna M. , Hulkova H. , Matignon M. , Hodanova K. , Vylet'al P. , Kalbacova M. , Baresova V. , Sikora J. , Blazkova H. , Zivny J. , Ivanek R. , Stranecky V. , Sovova J. , Claes K. , Lerut E. , Fryns J.P. , Hart P.S. , Hart T.C. , more...
Am. J. Hum. Genet.85:204-213(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HNFJ2 ARG-16;CHARACTERIZATION OF VARIANT HNFJ2 ARG-16

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