Gene name:
SLC12A1 (NKCC2) ;
Protein name:
Solute carrier family 12 member 1 ;
Alternative:
Kidney-specific Na-K-Cl symporter ;Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 ;
Organism:
Rabbit (Oryctolagus cuniculus).
General Annotation
Function:
Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MSLNNSSSVF | LDSVPTNTNR | FQVNVINENH | ESCAAGIDNT | DPPHYEETSF |
100:
GDEQNRLRIS | FRPGNQECYD | NFLQTGETTK | TDASFHTYDS | HTNTYYLQTF |
150:
GHNTMDAVPK | IEYYRNTGSV | SGPKVNRPSL | LEIHEQLAKN | VAVTPGSADR |
200:
VANGEGMPGE | EHAENKEEDN | KAGAVKFGWV | KGVLVRCMLN | IWGVMLFIRL |
250:
SWIVGEAGIG | LGVVIILLST | MVTSITGLST | SAIATNGFVR | GGGAYYLISR |
300:
SLGPEFGGSI | GLIFAFANAV | AVAMYVVGFA | ETVVDLLKES | DSMMVDPTND |
350:
IRIIGSITVV | ILLGISVAGM | EWEAKAQVIL | LIILLIAIAN | FFIGTVIPSN |
400:
NEKKSRGFFN | YQASIFAENF | GPSFTKGEGF | FSVFAIFFPA | ATGILAGANI |
450:
SGDLEDPQDA | IPRGTMLAIF | ITTVAYIGVA | ICVGACVVRD | ATGSMNDTII |
500:
SGINCNGSAA | CGLGYDFSRC | RHEPCQYGLM | NNFQVMSMVS | GFGPLITAGI |
550:
FSATLSSALA | SLVSAAKVFQ | ALCKDNIYKA | LQFFAKGYGK | NNEPLRGYIL |
600:
TFVIAMAFIL | IAELNTIAPI | ISNFFLASYA | LINFSCFHAS | YAKSPGWRPA |
650:
YGIYNMWVSL | FGAVLCCAVM | FVINWWAAVI | TYVIEFFLYI | YVTYKKPDVN |
700:
WGSSTQALSY | VSALDNALEL | TTVEDHVKNF | RPQCFVLTGG | PMTRPALLDI |
750:
TYAFTKNSGL | CICCEVFVGP | RKLCVKEMNS | GMAKKQAWLI | KNKIKAFYAA |
800:
VAADCFRDGV | RSLLQASGLG | RMKPNTLVIG | YKKKWRKAPL | TEIENYVGII |
850:
HDAFDFEIGV | VIVRISQGFD | ISQVLQVQEE | LEKLEQERLA | LEATIKDNEC |
900:
EEGNGGIRGL | FKKVGKLNIT | KPTPKKDSSI | NTIQSMHVGE | FNQKLVEAST |
950:
QFKKKQGKGT | IDVWWLFDDG | GLTLLIPYIL | TLRKKWKDCK | LRIYVGGKIN |
1000:
RIEEEKIAMA | SLLSKFRIKF | ADIHVIGDIN | IKPNKESWKF | FEEMIEPYRL |
1050:
HESCKDLTTA | EKLKRETPWK | ITDAELEAVK | EKSYRQVRLN | ELLQEHSRAA |
1099:
NLIVLSLPVA | RKGSISDLLY | MAWLEILTKN | LPPVLLVRGN | HKNVLTFYS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Rabbit
Mouse
ELISA Kit for Rabbit Solute carrier family 12 member 1
ELISA Kit for Rabbit Solute carrier family 12 member 1
ELISA Kit for Rabbit Solute carrier family 12 member 1
ELISA Kit for Rabbit Solute carrier family 12 member 1
CLIA Kit for Rabbit Solute carrier family 12 member 1
CLIA Kit for Rabbit Solute carrier family 12 member 1
CLIA Kit for Rabbit Solute carrier family 12 member 1
CLIA Kit for Rabbit Solute carrier family 12 member 1
Polyclonal Antibody for Rabbit Solute carrier family 12 member 1
Polyclonal Antibody for Rabbit Solute carrier family 12 member 1
Polyclonal Antibody for Rabbit Solute carrier family 12 member 1
Polyclonal Antibody for Rabbit Solute carrier family 12 member 1
Monoclonal Antibody for Rabbit Solute carrier family 12 member 1
Monoclonal Antibody for Rabbit Solute carrier family 12 member 1
Monoclonal Antibody for Rabbit Solute carrier family 12 member 1
Monoclonal Antibody for Rabbit Solute carrier family 12 member 1
Protein for Rabbit Solute carrier family 12 member 1
Protein for Rabbit Solute carrier family 12 member 1
Protein for Rabbit Solute carrier family 12 member 1
Protein for Rabbit Solute carrier family 12 member 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A; B AND F)
strain :
New Zealand white .
tissue :
Kidney .