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Index > Protein center > SLC12A2(Gene name) > Human
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  • SLC12A2 (Gene name),
  • Solute carrier family 12 member 2 (Protein name ),  S12A2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SLC12A2(NKCC1);
    Protein name:
    Solute carrier family 12 member 2;
    Alternative:
    Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1;Basolateral Na-K-Cl symporter;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1212
    Sequence:
    50:
    MEPRPTAPSS | GAPGLAGVGE | TPSAAALAAA | RVELPGTAVP | SVPEDAAPAS | 
    100:
    RDGGGVRDEG | PAAAGDGLGR | PLGPTPSQSR | FQVDLVSENA | GRAAAAAAAA | 
    150:
    AAAAAAAGAG | AGAKQTPADG | EASGESEPAK | GSEEAKGRFR | VNFVDPAASS | 
    200:
    SAEDSLSDAA | GVGVDGPNVS | FQNGGDTVLS | EGSSLHSGGG | GGSGHHQHYY | 
    250:
    YDTHTNTYYL | RTFGHNTMDA | VPRIDHYRHT | AAQLGEKLLR | PSLAELHDEL | 
    300:
    EKEPFEDGFA | NGEESTPTRD | AVVTYTAESK | GVVKFGWIKG | VLVRCMLNIW | 
    350:
    GVMLFIRLSW | IVGQAGIGLS | VLVIMMATVV | TTITGLSTSA | IATNGFVRGG | 
    400:
    GAYYLISRSL | GPEFGGAIGL | IFAFANAVAV | AMYVVGFAET | VVELLKEHSI | 
    450:
    LMIDEINDIR | IIGAITVVIL | LGISVAGMEW | EAKAQIVLLV | ILLLAIGDFV | 
    500:
    IGTFIPLESK | KPKGFFGYKS | EIFNENFGPD | FREEETFFSV | FAIFFPAATG | 
    550:
    ILAGANISGD | LADPQSAIPK | GTLLAILITT | LVYVGIAVSV | GSCVVRDATG | 
    600:
    NVNDTIVTEL | TNCTSAACKL | NFDFSSCESS | PCSYGLMNNF | QVMSMVSGFT | 
    650:
    PLISAGIFSA | TLSSALASLV | SAPKIFQALC | KDNIYPAFQM | FAKGYGKNNE | 
    700:
    PLRGYILTFL | IALGFILIAE | LNVIAPIISN | FFLASYALIN | FSVFHASLAK | 
    750:
    SPGWRPAFKY | YNMWISLLGA | ILCCIVMFVI | NWWAALLTYV | IVLGLYIYVT | 
    800:
    YKKPDVNWGS | STQALTYLNA | LQHSIRLSGV | EDHVKNFRPQ | CLVMTGAPNS | 
    850:
    RPALLHLVHD | FTKNVGLMIC | GHVHMGPRRQ | AMKEMSIDQA | KYQRWLIKNK | 
    900:
    MKAFYAPVHA | DDLREGAQYL | MQAAGLGRMK | PNTLVLGFKK | DWLQADMRDV | 
    950:
    DMYINLFHDA | FDIQYGVVVI | RLKEGLDISH | LQGQEELLSS | QEKSPGTKDV | 
    1000:
    VVSVEYSKKS | DLDTSKPLSE | KPITHKVEEE | DGKTATQPLL | KKESKGPIVP | 
    1050:
    LNVADQKLLE | ASTQFQKKQG | KNTIDVWWLF | DDGGLTLLIP | YLLTTKKKWK | 
    1100:
    DCKIRVFIGG | KINRIDHDRR | AMATLLSKFR | IDFSDIMVLG | DINTKPKKEN | 
    1150:
    IIAFEEIIEP | YRLHEDDKEQ | DIADKMKEDE | PWRITDNELE | LYKTKTYRQI | 
    1200:
    RLNELLKEHS | STANIIVMSL | PVARKGAVSS | ALYMAWLEAL | SKDLPPILLV | 
    1212:
    RGNHQSVLTF | YS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    UniGene:
    String:
    MIM:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Solute carrier family 12 member 2
    Cat.:
    E0313h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Solute carrier family 12 member 2
    Cat.:
    E0313m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Solute carrier family 12 member 2
    Cat.:
    U0313h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Solute carrier family 12 member 2
    Cat.:
    U0313m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Solute carrier family 12 member 2
    Cat.:
    P0313Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Solute carrier family 12 member 2
    Cat.:
    P0313Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Solute carrier family 12 member 2
    Monoclonal Antibody for Human Solute carrier family 12 member 2
    Protein for Human Solute carrier family 12 member 2
    Protein for Human Solute carrier family 12 member 2

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Primary structure, functional expression, and chromosomal localization of the bumetanide-sensitive Na-K-Cl cotransporter in human colon."
      Payne J.A. , Xu J.-C. , Haas M. , Lytle Y.C. , Ward D. , Forbush B. III
      J. Biol. Chem.270:17977-17985(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Colon.
    2. 2.
      "Quantitation of Na(+)-K(+)-2Cl(-) cotransport splice variants in human tissues using kinetic polymerase chain reaction."
      Vibat C.R. , Holland M.J. , Kang J.J. , Putney L.K. , O'Donnell M.E.
      Anal. Biochem.298:218-230(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 740-1066 (ISOFORM 2)
      tissue: Eye.
    3. 3.
      "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T. , Yi W. , Lu B. , Park S.K. , Xu T. , Lee J.-D. , Yates J.R. III
      J. Proteome Res.7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-77 AND SER-79;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION
    6. 6.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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