Gene name:
SLC12A2 (NKCC1) ;
Protein name:
Solute carrier family 12 member 2 ;
Alternative:
Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1 ;Basolateral Na-K-Cl symporter ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MEPRPTAPSS | GAPGLAGVGE | TPSAAALAAA | RVELPGTAVP | SVPEDAAPAS |
100:
RDGGGVRDEG | PAAAGDGLGR | PLGPTPSQSR | FQVDLVSENA | GRAAAAAAAA |
150:
AAAAAAAGAG | AGAKQTPADG | EASGESEPAK | GSEEAKGRFR | VNFVDPAASS |
200:
SAEDSLSDAA | GVGVDGPNVS | FQNGGDTVLS | EGSSLHSGGG | GGSGHHQHYY |
250:
YDTHTNTYYL | RTFGHNTMDA | VPRIDHYRHT | AAQLGEKLLR | PSLAELHDEL |
300:
EKEPFEDGFA | NGEESTPTRD | AVVTYTAESK | GVVKFGWIKG | VLVRCMLNIW |
350:
GVMLFIRLSW | IVGQAGIGLS | VLVIMMATVV | TTITGLSTSA | IATNGFVRGG |
400:
GAYYLISRSL | GPEFGGAIGL | IFAFANAVAV | AMYVVGFAET | VVELLKEHSI |
450:
LMIDEINDIR | IIGAITVVIL | LGISVAGMEW | EAKAQIVLLV | ILLLAIGDFV |
500:
IGTFIPLESK | KPKGFFGYKS | EIFNENFGPD | FREEETFFSV | FAIFFPAATG |
550:
ILAGANISGD | LADPQSAIPK | GTLLAILITT | LVYVGIAVSV | GSCVVRDATG |
600:
NVNDTIVTEL | TNCTSAACKL | NFDFSSCESS | PCSYGLMNNF | QVMSMVSGFT |
650:
PLISAGIFSA | TLSSALASLV | SAPKIFQALC | KDNIYPAFQM | FAKGYGKNNE |
700:
PLRGYILTFL | IALGFILIAE | LNVIAPIISN | FFLASYALIN | FSVFHASLAK |
750:
SPGWRPAFKY | YNMWISLLGA | ILCCIVMFVI | NWWAALLTYV | IVLGLYIYVT |
800:
YKKPDVNWGS | STQALTYLNA | LQHSIRLSGV | EDHVKNFRPQ | CLVMTGAPNS |
850:
RPALLHLVHD | FTKNVGLMIC | GHVHMGPRRQ | AMKEMSIDQA | KYQRWLIKNK |
900:
MKAFYAPVHA | DDLREGAQYL | MQAAGLGRMK | PNTLVLGFKK | DWLQADMRDV |
950:
DMYINLFHDA | FDIQYGVVVI | RLKEGLDISH | LQGQEELLSS | QEKSPGTKDV |
1000:
VVSVEYSKKS | DLDTSKPLSE | KPITHKVEEE | DGKTATQPLL | KKESKGPIVP |
1050:
LNVADQKLLE | ASTQFQKKQG | KNTIDVWWLF | DDGGLTLLIP | YLLTTKKKWK |
1100:
DCKIRVFIGG | KINRIDHDRR | AMATLLSKFR | IDFSDIMVLG | DINTKPKKEN |
1150:
IIAFEEIIEP | YRLHEDDKEQ | DIADKMKEDE | PWRITDNELE | LYKTKTYRQI |
1200:
RLNELLKEHS | STANIIVMSL | PVARKGAVSS | ALYMAWLEAL | SKDLPPILLV |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Solute carrier family 12 member 2
ELISA Kit for Human Solute carrier family 12 member 2
CLIA Kit for Human Solute carrier family 12 member 2
CLIA Kit for Human Solute carrier family 12 member 2
Polyclonal Antibody for Human Solute carrier family 12 member 2
Polyclonal Antibody for Human Solute carrier family 12 member 2
Monoclonal Antibody for Human Solute carrier family 12 member 2
Monoclonal Antibody for Human Solute carrier family 12 member 2
Protein for Human Solute carrier family 12 member 2
Protein for Human Solute carrier family 12 member 2
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Colon .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 740-1066 (ISOFORM 2)
tissue :
Eye .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-77 AND SER-79;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ENZYME REGULATION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]