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Index > Protein center > STAT3(Gene name) > Human
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  • STAT3 (Gene name),
  • Signal transducer and activator of transcription 3 (Protein name ),  STAT3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    STAT3(APRF);
    Protein name:
    Signal transducer and activator of transcription 3;
    Alternative:
    Acute-phase response factor;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Forms a homodimer or a heterodimer with a related family member (at least STAT1). Interacts with IL31RA, NCOA1, PELP1, SIPAR, SOCS7, STATIP1 and TMF1. Interacts with HCV core protein. Interacts with IL23R in presence of IL23. Interacts (via SH2 domain) with NLK. Interacts with ARL2BP; the interaction is enhanced by LIF and JAK1 expression (By similarity). Interacts with KPNA4 and KPNA5; KPNA4 may be the primary mediator of nuclear import (By similarity). Interacts with CAV2; the interaction is increased on insulin-induced tyrosine phosphorylation of CAV2 and leads to STAT3 activation (By similarity). Interacts with ARL2BP; interaction is enhanced with ARL2. Interacts with NEK6 (By similarity). Binds to CDK9 when activated and nuclear. Interacts with BMX.
    Function:
    Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA.
    Subcellular Location:
    Cytoplasm Nucleus Shuttles between the nucleus and the cytoplasm. Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4. Constitutive nuclear presence is independent of tyrosine phosphorylation. Predominantly present in the cytoplasm without stimuli. Upon leukemia inhibitory factor (LIF) stimulation, accumulates in the nucleus. The complex composed of BART and ARL2 plays an important role in the nuclear translocation and retention of STAT3.
    Protein Attributes:
    Sequence length:
    770
    Sequence:
    50:
    MAQWNQLQQL | DTRYLEQLHQ | LYSDSFPMEL | RQFLAPWIES | QDWAYAASKE | 
    100:
    SHATLVFHNL | LGEIDQQYSR | FLQESNVLYQ | HNLRRIKQFL | QSRYLEKPME | 
    150:
    IARIVARCLW | EESRLLQTAA | TAAQQGGQAN | HPTAAVVTEK | QQMLEQHLQD | 
    200:
    VRKRVQDLEQ | KMKVVENLQD | DFDFNYKTLK | SQGDMQDLNG | NNQSVTRQKM | 
    250:
    QQLEQMLTAL | DQMRRSIVSE | LAGLLSAMEY | VQKTLTDEEL | ADWKRRQQIA | 
    300:
    CIGGPPNICL | DRLENWITSL | AESQLQTRQQ | IKKLEELQQK | VSYKGDPIVQ | 
    350:
    HRPMLEERIV | ELFRNLMKSA | FVVERQPCMP | MHPDRPLVIK | TGVQFTTKVR | 
    400:
    LLVKFPELNY | QLKIKVCIDK | DSGDVAALRG | SRKFNILGTN | TKVMNMEESN | 
    450:
    NGSLSAEFKH | LTLREQRCGN | GGRANCDASL | IVTEELHLIT | FETEVYHQGL | 
    500:
    KIDLETHSLP | VVVISNICQM | PNAWASILWY | NMLTNNPKNV | NFFTKPPIGT | 
    550:
    WDQVAEVLSW | QFSSTTKRGL | SIEQLTTLAE | KLLGPGVNYS | GCQITWAKFC | 
    600:
    KENMAGKGFS | FWVWLDNIID | LVKKYILALW | NEGYIMGFIS | KERERAILST | 
    650:
    KPPGTFLLRF | SESSKEGGVT | FTWVEKDISG | KTQIQSVEPY | TKQQLNNMSF | 
    700:
    AEIIMGYKIM | DATNILVSPL | VYLYPDIPKE | EAFGKYCRPE | SQEHPEADPG | 
    750:
    SAAPYLKTKF | ICVTPTTCSN | TIDLPMSPRT | LDSLMQFGNN | GEGAEPSAGG | 
    770:
    QFESLTFDME | LTSECATSPM | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    MIM:
    Pfam:
    SMR:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Signal transducer and activator of transcription 3
    Cat.:
    E1743m
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    96T
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    ELISA Kit for Human Signal transducer and activator of transcription 3
    Cat.:
    E1743r
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    96T
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    ELISA Kit for Human Signal transducer and activator of transcription 3
    Cat.:
    E1743p
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    96T
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    ELISA Kit for Human Signal transducer and activator of transcription 3
    Cat.:
    E1743b
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    96T
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    ELISA Kit for Human Signal transducer and activator of transcription 3
    Cat.:
    E1743h
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    96T
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    ELISA Kit for Human Signal transducer and activator of transcription 3
    Cat.:
    E1743c
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    Packing:
    96T
    CLIA Kit for Human Signal transducer and activator of transcription 3
    Cat.:
    U1743c
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Signal transducer and activator of transcription 3
    Cat.:
    U1743m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Signal transducer and activator of transcription 3
    Cat.:
    U1743h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    CLIA Kit for Human Signal transducer and activator of transcription 3
    Cat.:
    U1743p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Signal transducer and activator of transcription 3
    Cat.:
    U1743r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Signal transducer and activator of transcription 3
    Cat.:
    U1743b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Signal transducer and activator of transcription 3
    Cat.:
    P1743Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Signal transducer and activator of transcription 3
    Cat.:
    P1743Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Signal transducer and activator of transcription 3
    Polyclonal Antibody for Human Signal transducer and activator of transcription 3
    Cat.:
    P1743Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Signal transducer and activator of transcription 3
    Polyclonal Antibody for Human Signal transducer and activator of transcription 3
    Monoclonal Antibody for Human Signal transducer and activator of transcription 3
    Monoclonal Antibody for Human Signal transducer and activator of transcription 3
    Monoclonal Antibody for Human Signal transducer and activator of transcription 3
    Monoclonal Antibody for Human Signal transducer and activator of transcription 3
    Monoclonal Antibody for Human Signal transducer and activator of transcription 3
    Monoclonal Antibody for Human Signal transducer and activator of transcription 3
    Protein for Human Signal transducer and activator of transcription 3
    Protein for Human Signal transducer and activator of transcription 3
    Protein for Human Signal transducer and activator of transcription 3
    Protein for Human Signal transducer and activator of transcription 3
    Protein for Human Signal transducer and activator of transcription 3
    Protein for Human Signal transducer and activator of transcription 3

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    Linearity
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    References
    1. 1.
      "Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway."
      Akira S. , Nishio Y. , Inoue M. , Wang X.-J. , Wei S. , Matsusaka T. , Yoshida K. , Sudo T. , Naruto M. , Kishimoto T.
      Cell77:63-71(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT TYR-561
      tissue: Placenta.
    2. 2.
      "Highly conserved amino-acid sequence between murine STAT3 and a revised human STAT3 sequence."
      Della Pietra L. , Bressan A. , Pezzotti A. , Serlupi-Crescenzi O.
      Gene213:119-124(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Methods for treating chronic kidney disease."
      Feinstein E. , Adamsky S. , Erlich S. , Molitoris B.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    5. 5.
      SeattleSNPs variation discovery resource
      Submitted (2004-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ILE-143
    6. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND DEL-701)
      tissue: Kidney.
      tissue: Pancreas.
    8. 9.
      Della Pietra L. , Bressan A. , Pezzotti A.R. , Serlupi-Crescenzi O.
      Submitted (1997-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 564-704
      tissue: Liver.
    9. 10.
      "Requirement of serine phosphorylation for formation of STAT-promoter complexes."
      Zhang X. , Blenis J. , Li H.-C. , Schindler C. , Chen-Kiang S.
      Science267:1990-1994(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SERINE RESIDUES
    10. 11.
      "Specific inhibition of Stat3 signal transduction by PIAS3."
      Chung C.D. , Liao J. , Liu B. , Rao X. , Jay P. , Berta P. , Shuai K.
      Science278:1803-1805(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PIAS3
    11. 12.
      "Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation."
      Tsai Y.T. , Su Y.H. , Fang S.S. , Huang T.N. , Qiu Y. , Jou Y.S. , Shih H.M. , Kung H.J. , Chen R.H.
      Mol. Cell. Biol.20:2043-2054(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION BY BMX;INTERACTION WITH BMX;FUNCTION
    12. 13.
      "The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation."
      Yamamoto T. , Sekine Y. , Kashima K. , Kubota A. , Sato N. , Aoki N. , Matsuda T.
      Biochem. Biophys. Res. Commun.297:811-817(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN IL6 SIGNALING;PHOSPHORYLATION;DEPHOSPHORYLATION BY PTPN2
    13. 14.
      "Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a."
      Giraud S. , Bienvenu F. , Avril S. , Gascan H. , Heery D.M. , Coqueret O.
      J. Biol. Chem.277:8004-8011(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NCOA1
    14. 15.
      "Activation of STAT3 by the hepatitis C virus core protein leads to cellular transformation."
      Yoshida T. , Hanada T. , Tokuhisa T. , Kosai K. , Sata M. , Kohara M. , Yoshimura A.
      J. Exp. Med.196:641-653(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HCV CORE PROTEIN
    15. 16.
      "A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R."
      Parham C. , Chirica M. , Timans J. , Vaisberg E. , Travis M. , Cheung J. , Pflanz S. , Zhang R. , Singh K.P. , Vega F. , To W. , Wagner J. , O'Farrell A.-M. , McClanahan T.K. , Zurawski S. , Hannum C. , Gorman D. , Rennick D.M. , more...
      J. Immunol.168:5699-5708(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IL23R
    16. 17.
      "Identification and characterization of signal transducer and activator of transcription 3 recruitment sites within the epidermal growth factor receptor."
      Shao H. , Cheng H.Y. , Cook R.G. , Tweardy D.J.
      Cancer Res.63:3923-3930(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN EGFR SIGNALING;INTERACTION WITH EGFR
    17. 18.
      "Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway."
      Wierenga A.T. , Vogelzang I. , Eggen B.J. , Vellenga E.
      Exp. Hematol.31:398-405(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-705 AND SER-727
    18. 19.
      "Signal transduction via the stem cell factor receptor/c-Kit."
      Ronnstrand L.
      Cell. Mol. Life Sci.61:2535-2548(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON ROLE IN KIT SIGNALING
    19. 20.
      "Characterization of the signaling capacities of the novel gp130-like cytokine receptor."
      Dreuw A. , Radtke S. , Pflanz S. , Lippok B.E. , Heinrich P.C. , Hermanns H.M.
      J. Biol. Chem.279:36112-36120(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH IL31RA
    20. 21.
      "IRAK1 serves as a novel regulator essential for lipopolysaccharide-induced interleukin-10 gene expression."
      Huang Y. , Li T. , Sane D.C. , Li L.
      J. Biol. Chem.279:51697-51703(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-727 BY IRAK1
    21. 22.
      "TMF/ARA160 is a BC-box-containing protein that mediates the degradation of Stat3."
      Perry E. , Tsruya R. , Levitsky P. , Pomp O. , Taller M. , Weisberg S. , Parris W. , Kulkarni S. , Malovani H. , Pawson T. , Shpungin S. , Nir U.
      Oncogene23:8908-8919(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TMF1
    22. 23.
      "Proline-, glutamic acid-, and leucine-rich protein-1 is essential in growth factor regulation of signal transducers and activators of transcription 3 activation."
      Manavathi B. , Nair S.S. , Wang R.-A. , Kumar R. , Vadlamudi R.K.
      Cancer Res.65:5571-5577(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PELP1
    23. 24.
      "Physical and functional interactions between STAT3 and ZIP kinase."
      Sato N. , Kawai T. , Sugiyama K. , Muromoto R. , Imoto S. , Sekine Y. , Ishida M. , Akira S. , Matsuda T.
      Int. Immunol.17:1543-1552(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-727 BY ZIPK/DAPK3;INTERACTION WITH ZIPK/DAPK3;SUBCELLULAR LOCATION
    24. 25.
      "Suppressor of cytokine signaling 7 inhibits prolactin, growth hormone, and leptin signaling by interacting with STAT5 or STAT3 and attenuating their nuclear translocation."
      Martens N. , Uzan G. , Wery M. , Hooghe R. , Hooghe-Peters E.L. , Gertler A.
      J. Biol. Chem.280:13817-13823(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SOCS7
    25. 26.
      "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."
      Rush J. , Moritz A. , Lee K.A. , Guo A. , Goss V.L. , Spek E.J. , Zhang H. , Zha X.-M. , Polakiewicz R.D. , Comb M.J.
      Nat. Biotechnol.23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-705;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-704 (ISOFORM DEL-701);IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    26. 27.
      "Identification of STAT3 as a specific substrate of breast tumor kinase."
      Liu L. , Gao Y. , Qiu H. , Miller W.T. , Poli V. , Reich N.C.
      Oncogene25:4904-4912(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-705 BY PTK6
    27. 28.
      "Protein kinase Cepsilon interacts with signal transducers and activators of transcription 3 (Stat3), phosphorylates Stat3Ser727, and regulates its constitutive activation in prostate cancer."
      Aziz M.H. , Manoharan H.T. , Church D.R. , Dreckschmidt N.E. , Zhong W. , Oberley T.D. , Wilding G. , Verma A.K.
      Cancer Res.67:8828-8838(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PRKCE;PHOSPHORYLATION AT SER-727
    28. 29.
      "STAT3 nuclear import is independent of tyrosine phosphorylation and mediated by importin-alpha3."
      Liu L. , McBride K.M. , Reich N.C.
      Proc. Natl. Acad. Sci. U.S.A.102:8150-8155(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;NUCLEAR IMPORT MOTIF
    29. 30.
      "The functional role of an interleukin 6-inducible CDK9.STAT3 complex in human gamma-fibrinogen gene expression."
      Hou T. , Ray S. , Brasier A.R.
      J. Biol. Chem.282:37091-37102(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CDK9
    30. 31.
      "Role for DYRK family kinases on regulation of apoptosis."
      Yoshida K.
      Biochem. Pharmacol.76:1389-1394(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-727 BY DYRK2
    31. 32.
      "Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts."
      Tauzin S. , Ding H. , Khatib K. , Ahmad I. , Burdevet D. , van Echten-Deckert G. , Lindquist J.A. , Schraven B. , Din N.U. , Borisch B. , Hoessli D.C.
      Blood111:2310-2320(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH LYN AND PAG1
    32. 33.
      "BART is essential for nuclear retention of STAT3."
      Muromoto R. , Sekine Y. , Imoto S. , Ikeda O. , Okayama T. , Sato N. , Matsuda T.
      Int. Immunol.20:395-403(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ARL2BP;PHOSPHORYLATION AT SERINE RESIDUES;SUBCELLULAR LOCATION
    33. 34.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-727;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    34. 35.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-727;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    35. 36.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    36. 37.
      "The Fer tyrosine kinase cooperates with interleukin-6 to activate signal transducer and activator of transcription 3 and promote human prostate cancer cell growth."
      Zoubeidi A. , Rocha J. , Zouanat F.Z. , Hamel L. , Scarlata E. , Aprikian A.G. , Chevalier S.
      Mol. Cancer Res.7:142-155(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FER;PHOSPHORYLATION BY FER
    37. 38.
      "Acetylation directs survivin nuclear localization to repress STAT3 oncogenic activity."
      Wang H. , Holloway M.P. , Ma L. , Cooper Z.A. , Riolo M. , Samkari A. , Elenitoba-Johnson K.S. , Chin Y.E. , Altura R.A.
      J. Biol. Chem.285:36129-36137(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BIRC5/SURVIVIN
    38. 39.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-727;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    39. 40.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    40. 41.
      "Mechanisms of STAT protein activation by oncogenic KIT mutants in neoplastic mast cells."
      Chaix A. , Lopez S. , Voisset E. , Gros L. , Dubreuil P. , De Sepulveda P.
      J. Biol. Chem.286:5956-5966(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-705 IN RESPONSE TO KIT SIGNALING;PHOSPHORYLATION AT SER-727
    41. 42.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH EIF2AK2
    42. 43.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    43. 44.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    44. 45.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AD-HIES GLN-382; LEU-382; TRP-382; LEU-384; SER-384; GLN-423; VAL-463 DEL; ASN-611; VAL-621; ILE-622; LEU-637; MET-637; GLN-644 DEL AND CYS-657
    45. 46.
      "Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome."
      Minegishi Y. , Saito M. , Tsuchiya S. , Tsuge I. , Takada H. , Hara T. , Kawamura N. , Ariga T. , Pasic S. , Stojkovic O. , Metin A. , Karasuyama H.
      Nature448:1058-1062(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AD-HIES GLN-382; TRP-382; ILE-389; TYR-437 AND VAL-463 DEL;CHARACTERIZATION OF VARIANTS AD-HIES GLN-382; TRP-382; ILE-389; TYR-437 AND VAL-463 DEL
    46. 47.
      "Signal transducer and activator of transcription 3 mutation with invasive eosinophilic disease."
      Crosby K. , Swender D. , Chernin L. , Hafez-Khayyata S. , Ochs H. , Tcheurekdjian H. , Hostoffer R.
      Allergy Rhinol. (Providence)3:E94-E97(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AD-HIES ILE-389
    47. 48.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN ADMIO;VARIANTS ADMIO ARG-392; LYS-646; ASN-658 AND MET-716
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