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Index > Protein center > Snca(Gene name) > Mouse
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  • Snca (Gene name),
  • Alpha-synuclein (Protein name ),  SYUA_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Snca(Syn);
    Protein name:
    Alpha-synuclein;
    Alternative:
    Non-A4 component of amyloid precursor(NACP);Non-A beta component of AD amyloid;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with UCHL1.
    Function:
    May be involved in the regulation of dopamine release and transport.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    140
    Sequence:
    50:
    MDVFMKGLSK | AKEGVVAAAE | KTKQGVAEAA | GKTKEGVLYV | GSKTKEGVVH | 
    100:
    GVTTVAEKTK | EQVTNVGGAV | VTGVTAVAQK | TVEGAGNIAA | ATGFVKKDQM | 
    140:
    GKGEEGYPQE | GILEDMPVDP | GSEAYEMPSE | EGYQDYEPEA | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    UniGene:
    KEGG:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Alpha-synuclein
    Cat.:
    E1222m
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    Packing:
    96T
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    ELISA Kit for Mouse Alpha-synuclein
    Cat.:
    E1222r
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    96T
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    ELISA Kit for Mouse Alpha-synuclein
    Cat.:
    E1222h
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    96T
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    ELISA Kit for Mouse Alpha-synuclein
    Cat.:
    E1222b
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    Packing:
    96T
    ELISA Kit for Mouse Alpha-synuclein
    Cat.:
    E1222p
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Alpha-synuclein
    Cat.:
    U1222b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Alpha-synuclein
    Cat.:
    U1222h
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Alpha-synuclein
    Cat.:
    U1222r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Alpha-synuclein
    Cat.:
    U1222p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Alpha-synuclein
    Cat.:
    U1222m
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Alpha-synuclein
    Cat.:
    P1222Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Alpha-synuclein
    Cat.:
    P1222Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Alpha-synuclein
    Cat.:
    P1222Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Alpha-synuclein
    Polyclonal Antibody for Mouse Alpha-synuclein
    Monoclonal Antibody for Mouse Alpha-synuclein
    Monoclonal Antibody for Mouse Alpha-synuclein
    Monoclonal Antibody for Mouse Alpha-synuclein
    Monoclonal Antibody for Mouse Alpha-synuclein
    Monoclonal Antibody for Mouse Alpha-synuclein
    Protein for Mouse Alpha-synuclein
    Protein for Mouse Alpha-synuclein
    Protein for Mouse Alpha-synuclein
    Protein for Mouse Alpha-synuclein
    Protein for Mouse Alpha-synuclein

    R&D Technical Data
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         12% SDS-PAGE Analysis

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    Precision
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    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤ 3.7%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤ 6.1%

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    Recovery
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    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    94

    91-98

    Plasma

    93

    93-99

     

     

     

     

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    Linearity
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    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    92-96%

    90-99%

    91-101%

    92-104%

    EDTA plasma(n=5)

    89-95%

    93-101%

    89-94%

    90-102%

    heparin plasma(n=5)

    93-102%

     

    94-103%

    96-102%

    91-101%

     

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    References
    1. 1.
      "Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development."
      Hsu L.J. , Mallory M. , Xia Y. , Veinbergs I. , Hashimoto M. , Yoshimoto M. , Thal L.J. , Saitoh T. , Masliah E.
      J. Neurochem.71:338-344(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "The cDNA cloning and ontogeny of mouse alpha-synuclein."
      Hong L. , Ko H.W. , Gwag B.J. , Joe E. , Lee S. , Kim Y.T. , Suh Y.-H.
      NeuroReport9:1239-1243(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      strain: ICR.
    3. 3.
      "Genomic cloning of the mouse alpha-synuclein and analysis of the promoter."
      Fog J.U. , Kallunki P.
      Submitted (1999-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1)
      strain: C57BL/6J.
      strain: Sv129/Ola.
      tissue: Brain.
    4. 4.
      "Human and mouse alpha-synuclein genes: comparative genomic sequence analysis and identification of a novel gene regulatory element."
      Touchman J.W. , Dehejia A. , Chiba-Falek O. , Cabin D.E. , Schwartz J.R. , Orrison B.M. , Polymeropoulos M.H. , Nussbaum R.L.
      Genome Res.11:78-86(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: 129/SvJ.
    5. 5.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      strain: C57BL/6J.
      strain: NOD.
      tissue: Liver.
      tissue: Spleen.
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: C57BL/6.
      tissue: Brain.
    7. 7.
      "Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice."
      Schlueter O.M. , Fornai F. , Alessandri M.G. , Takamori S. , Geppert M. , Jahn R. , Suedhof T.C.
      Neuroscience118:985-1002(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-54
      strain: 129/SvJ.
    8. 8.
      Lubec G. , Klug S.
      Submitted (2007-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 61-96;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Hippocampus.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-129
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