Protein name:
T-box transcription factor TBX3 (T-box protein 3) ;
Alternative:
Organism:
Human (Homo sapiens).
General Annotation
Function:
Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MSLSMRDPVI | PGTSMAYHPF | LPHRAPDFAM | SAVLGHQPPF | FPALTLPPNG |
100:
AAALSLPGAL | AKPIMDQLVG | AAETGIPFSS | LGPQAHLRPL | KTMEPEEEVE |
150:
DDPKVHLEAK | ELWDQFHKRG | TEMVITKSGR | RMFPPFKVRC | SGLDKKAKYI |
200:
LLMDIIAADD | CRYKFHNSRW | MVAGKADPEM | PKRMYIHPDS | PATGEQWMSK |
250:
VVTFHKLKLT | NNISDKHGFT | LAFPSDHATW | QGNYSFGTQT | ILNSMHKYQP |
300:
RFHIVRANDI | LKLPYSTFRT | YLFPETEFIA | VTAYQNDKIT | QLKIDNNPFA |
350:
KGFRDTGNGR | REKRKQLTLQ | SMRVFDERHK | KENGTSDESS | SEQAAFNCFA |
400:
QASSPAASTV | GTSNLKDLCP | SEGESDAEAE | SKEEHGPEAC | DAAKISTTTS |
450:
EEPCRDKGSP | AVKAHLFAAE | RPRDSGRLDK | ASPDSRHSPA | TISSSTRGLG |
500:
AEERRSPVRE | GTAPAKVEEA | RALPGKEAFA | PLTVQTDAAA | AHLAQGPLPG |
550:
LGFAPGLAGQ | QFFNGHPLFL | HPSQFAMGGA | FSSMAAAGMG | PLLATVSGAS |
600:
TGVSGLDSTA | MASAAAAQGL | SGASAATLPF | HLQQHVLASQ | GLAMSPFGSL |
650:
FPYPYTYMAA | AAAASSAAAS | SSVHRHPFLN | LNTMRPRLRY | SPYSIPVPVP |
700:
DGSSLLTTAL | PSMAAAAGPL | DGKVAALAAS | PASVAVDSGS | ELNSRSSTLS |
743:
SSSMSLSPKL | CAEKEAATSE | LQSIQRLVSG | LEAKPDRSRS | ASP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Mouse
Human
Chicken
ELISA Kit for Human T-box protein 3
ELISA Kit for Human T-box protein 3
ELISA Kit for Human T-box protein 3
ELISA Kit for Human T-box protein 3
CLIA Kit for Human T-box protein 3
CLIA Kit for Human T-box protein 3
CLIA Kit for Human T-box protein 3
CLIA Kit for Human T-box protein 3
Polyclonal Antibody for Human T-box protein 3
Polyclonal Antibody for Human T-box protein 3
Polyclonal Antibody for Human T-box protein 3
Polyclonal Antibody for Human T-box protein 3
Monoclonal Antibody for Human T-box protein 3
Monoclonal Antibody for Human T-box protein 3
Monoclonal Antibody for Human T-box protein 3
Monoclonal Antibody for Human T-box protein 3
Protein for Human T-box protein 3
Protein for Human T-box protein 3
Protein for Human T-box protein 3
Protein for Human T-box protein 3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM I);FUNCTION
tissue :
Mammary carcinoma .
2.
"Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome."
Bamshad M.
,
Lin R.C.
,
Law D.J.
,
Watkins W.S.
,
Krakowiak P.A.
,
Moore M.E.
,
Franceschini P.
,
Lala R.
,
Holmes L.B.
,
Gebuhr T.C.
,
Schinzel A.
,
Bruneau B.G.
,
Seidman J.G.
,
Seidman C.E.
,
Jorde L.B.
Nat. Genet.16:311-315(1997)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-488 (ISOFORM I)
tissue :
Kidney .
3.
"The spectrum of mutations in TBX3: genotype/phenotype relationship in ulnar-mammary syndrome."
Bamshad M.
,
Le T.
,
Watkins W.S.
,
Dixon M.E.
,
Kramer B.E.
,
Roeder A.D.
,
Carey J.C.
,
Root S.
,
Schinzel A.
,
Van Maldergem L.
,
Gardner R.J.M.
,
Lin R.C.
,
Seidman C.E.
,
Seidman J.G.
,
Wallerstein R.
,
Moran E.
,
Sutphen R.
,
Campbell C.E.
,
Jorde L.B.
more...
Am. J. Hum. Genet.64:1550-1562(1999)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 592-743;ALTERNATIVE SPLICING;VARIANTS UMS PRO-143 AND SER-149
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM III)
tissue :
Adrenal gland .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM II)
tissue :
Brain .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-432 AND SER-438;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-371; SER-707; SER-738; SER-740 AND SER-742;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH PML
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 101-311