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Index > Protein center > TBX3(Gene name) > Human
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  • TBX3 (Gene name),
  • T-box transcription factor TBX3 (Protein name ),  TBX3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    TBX3;
    Protein name:
    T-box transcription factor TBX3(T-box protein 3);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    743
    Sequence:
    50:
    MSLSMRDPVI | PGTSMAYHPF | LPHRAPDFAM | SAVLGHQPPF | FPALTLPPNG | 
    100:
    AAALSLPGAL | AKPIMDQLVG | AAETGIPFSS | LGPQAHLRPL | KTMEPEEEVE | 
    150:
    DDPKVHLEAK | ELWDQFHKRG | TEMVITKSGR | RMFPPFKVRC | SGLDKKAKYI | 
    200:
    LLMDIIAADD | CRYKFHNSRW | MVAGKADPEM | PKRMYIHPDS | PATGEQWMSK | 
    250:
    VVTFHKLKLT | NNISDKHGFT | LAFPSDHATW | QGNYSFGTQT | ILNSMHKYQP | 
    300:
    RFHIVRANDI | LKLPYSTFRT | YLFPETEFIA | VTAYQNDKIT | QLKIDNNPFA | 
    350:
    KGFRDTGNGR | REKRKQLTLQ | SMRVFDERHK | KENGTSDESS | SEQAAFNCFA | 
    400:
    QASSPAASTV | GTSNLKDLCP | SEGESDAEAE | SKEEHGPEAC | DAAKISTTTS | 
    450:
    EEPCRDKGSP | AVKAHLFAAE | RPRDSGRLDK | ASPDSRHSPA | TISSSTRGLG | 
    500:
    AEERRSPVRE | GTAPAKVEEA | RALPGKEAFA | PLTVQTDAAA | AHLAQGPLPG | 
    550:
    LGFAPGLAGQ | QFFNGHPLFL | HPSQFAMGGA | FSSMAAAGMG | PLLATVSGAS | 
    600:
    TGVSGLDSTA | MASAAAAQGL | SGASAATLPF | HLQQHVLASQ | GLAMSPFGSL | 
    650:
    FPYPYTYMAA | AAAASSAAAS | SSVHRHPFLN | LNTMRPRLRY | SPYSIPVPVP | 
    700:
    DGSSLLTTAL | PSMAAAAGPL | DGKVAALAAS | PASVAVDSGS | ELNSRSSTLS | 
    743:
    SSSMSLSPKL | CAEKEAATSE | LQSIQRLVSG | LEAKPDRSRS | ASP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    UniGene:
    UniGene:
    MIM:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human T-box protein 3
    Cat.:
    E13609r
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human T-box protein 3
    Cat.:
    E13609m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human T-box protein 3
    Cat.:
    E13609h
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human T-box protein 3
    MSDS:
    Please sign in first.
    CLIA Kit for Human T-box protein 3
    MSDS:
    Please sign in first.
    CLIA Kit for Human T-box protein 3
    Cat.:
    U13609m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human T-box protein 3
    Cat.:
    U13609h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human T-box protein 3
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Human T-box protein 3
    Polyclonal Antibody for Human T-box protein 3
    Polyclonal Antibody for Human T-box protein 3
    Polyclonal Antibody for Human T-box protein 3
    Monoclonal Antibody for Human T-box protein 3
    Monoclonal Antibody for Human T-box protein 3
    Monoclonal Antibody for Human T-box protein 3
    Monoclonal Antibody for Human T-box protein 3
    Protein for Human T-box protein 3
    Protein for Human T-box protein 3
    Protein for Human T-box protein 3
    Protein for Human T-box protein 3

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    References
    1. 1.
      "Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome."
      He M.-L. , Wen L. , Campbell C.E. , Wu J.Y. , Rao Y.
      Proc. Natl. Acad. Sci. U.S.A.96:10212-10217(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM I);FUNCTION
      tissue: Mammary carcinoma.
    2. 2.
      "Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome."
      Bamshad M. , Lin R.C. , Law D.J. , Watkins W.S. , Krakowiak P.A. , Moore M.E. , Franceschini P. , Lala R. , Holmes L.B. , Gebuhr T.C. , Schinzel A. , Bruneau B.G. , Seidman J.G. , Seidman C.E. , Jorde L.B.
      Nat. Genet.16:311-315(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-488 (ISOFORM I)
      tissue: Kidney.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 592-743;ALTERNATIVE SPLICING;VARIANTS UMS PRO-143 AND SER-149
    4. 4.
      "A novel gene expressed in human adrenal gland."
      Song H. , Gao G. , Peng Y. , Ren S. , Chen Z. , Han Z.
      Submitted (1999-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM III)
      tissue: Adrenal gland.
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM II)
      tissue: Brain.
    6. 6.
      "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T. , Yi W. , Lu B. , Park S.K. , Xu T. , Lee J.-D. , Yates J.R. III
      J. Proteome Res.7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-432 AND SER-438;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-371; SER-707; SER-738; SER-740 AND SER-742;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 8.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "Physical and functional interaction between PML and TBX2 in the establishment of cellular senescence."
      Martin N. , Benhamed M. , Nacerddine K. , Demarque M.D. , van Lohuizen M. , Dejean A. , Bischof O.
      EMBO J.31:95-109(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PML
    10. 10.
      "Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome."
      Coll M. , Seidman J.G. , Muller C.W.
      Structure10:343-356(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS) OF 101-311
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