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Index > Protein center > TFPI2(Gene name) > Human
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  • TFPI2 (Gene name),
  • Tissue factor pathway inhibitor 2 (Protein name ),  TFPI2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    TFPI2;
    Protein name:
    Tissue factor pathway inhibitor 2(TFPI-2);
    Alternative:
    Placental protein 5(PP5);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    May play a role in the regulation of plasmin-mediated matrix remodeling. Inhibits trypsin, plasmin, factor VIIa/tissue factor and weakly factor Xa. Has no effect on thrombin.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    235
    Sequence:
    50:
    MDPARPLGLS | ILLLFLTEAA | LGDAAQEPTG | NNAEICLLPL | DYGPCRALLL | 
    100:
    RYYYDRYTQS | CRQFLYGGCE | GNANNFYTWE | ACDDACWRIE | KVPKVCRLQV | 
    150:
    SVDDQCEGST | EKYFFNLSSM | TCEKFFSGGC | HRNRIENRFP | DEATCMGFCA | 
    200:
    PKKIPSFCYS | PKDEGLCSAN | VTRYYFNPRY | RTCDAFTYTG | CGGNDNNFVS | 
    235:
    REDCKRACAK | ALKKKKKMPK | LRFASRIRKI | RKKQF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    UniGene:
    Pfam:
    MIM:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human TFPI-2
    Cat.:
    E1940h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human TFPI-2
    Cat.:
    E1940m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human TFPI-2
    Cat.:
    E1940b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human TFPI-2
    Cat.:
    U1940b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human TFPI-2
    Cat.:
    U1940h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human TFPI-2
    Cat.:
    U1940m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human TFPI-2
    Cat.:
    P1940Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human TFPI-2
    Polyclonal Antibody for Human TFPI-2
    Cat.:
    P1940Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human TFPI-2
    Monoclonal Antibody for Human TFPI-2
    Monoclonal Antibody for Human TFPI-2
    Protein for Human TFPI-2
    Protein for Human TFPI-2
    Protein for Human TFPI-2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "cDNA cloning and mRNA expression of a serine proteinase inhibitor secreted by cancer cells: identification as placental protein 5 and tissue factor pathway inhibitor-2."
      Miyagi Y. , Koshikawa N. , Yasumitsu H. , Miyagi E. , Hirahara F. , Aoki I. , Misugi K. , Umeda M. , Miyazaki K.
      J. Biochem.116:939-942(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE
      tissue: Placenta.
    2. 2.
      "Molecular cloning, expression, and partial characterization of a second human tissue-factor-pathway inhibitor."
      Sprecher C.A. , Kisiel W. , Mathewes S. , Foster D.C.
      Proc. Natl. Acad. Sci. U.S.A.91:3353-3357(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Placenta.
    3. 3.
      "Genomic structure and promoter activity of the human tissue factor pathway inhibitor-2 gene."
      Kamei S. , Kazama Y. , Kuijper J.L. , Foster D.C. , Kisiel W.
      Biochim. Biophys. Acta1517:430-435(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      Xu Y. , Li T. , Du G.
      Submitted (2004-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
      tissue: Placenta.
    6. 6.
      "The DNA sequence of human chromosome 7."
      Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
      Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    9. 10.
      "Novel extracellular matrix-associated serine proteinase inhibitors from human skin fibroblasts."
      Rao C.N. , Liu Y.Y. , Peavey C.L. , Woodley D.T.
      Arch. Biochem. Biophys.317:311-314(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 23-42;FUNCTION
      tissue: Fibroblast.
    10. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 23-35; 47-53 AND 133-146
      tissue: Placenta.
    11. 12.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    12. 13.
      "Crystal structure of Kunitz domain 1 (KD1) of tissue factor pathway inhibitor-2 in complex with trypsin. Implications for KD1 specificity of inhibition."
      Schmidt A.E. , Chand H.S. , Cascio D. , Kisiel W. , Bajaj S.P.
      J. Biol. Chem.280:27832-27838(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) OF 28-90 IN COMPLEX WITH BOVINE TRYPSIN;DISULFIDE BONDS
    13. 14.
      "Protein phosphatase complex PP5/PPP2R3C dephosphorylates P-glycoprotein/ABCB1 and down-regulates the expression and function."
      Katayama K. , Yamaguchi M. , Noguchi K. , Sugimoto Y.
      Cancer Lett.345:124-131(2014) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PPP2R3C
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