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Index > Protein center > TNFSF4(Gene name) > Human
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  • TNFSF4 (Gene name),
  • Tumor necrosis factor ligand superfamily member 4 (Protein name ),  TNFL4_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    TNFSF4(TXGP1);
    Protein name:
    Tumor necrosis factor ligand superfamily member 4;
    Alternative:
    OX40 ligand(OX40L);Glycoprotein Gp34;TAX transcriptionally-activated glycoprotein 1;
    CD:
    CD252;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotrimer.
    Function:
    Cytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.
    Subcellular Location:
    Membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    183
    Sequence:
    50:
    MERVQPLEEN | VGNAARPRFE | RNKLLLVASV | IQGLGLLLCF | TYICLHFSAL | 
    100:
    QVSHRYPRIQ | SIKVQFTEYK | KEKGFILTSQ | KEDEIMKVQN | NSVIINCDGF | 
    150:
    YLISLKGYFS | QEVNISLHYQ | KDEEPLFQLK | KVRSVNSLMV | ASLTYKDKVY | 
    183:
    LNVTTDNTSL | DDFHVNGGEL | ILIHQNPGEF | CVL
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    KEGG:
    SMR:
    MIM:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Tumor necrosis factor ligand superfamily member 4
    Cat.:
    E8964h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Tumor necrosis factor ligand superfamily member 4
    MSDS:
    Please sign in first.
    ELISA Kit for Human Tumor necrosis factor ligand superfamily member 4
    Cat.:
    E8964m
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    Packing:
    96T
    ELISA Kit for Human Tumor necrosis factor ligand superfamily member 4
    Cat.:
    E8964r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Tumor necrosis factor ligand superfamily member 4
    Cat.:
    U8964r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Tumor necrosis factor ligand superfamily member 4
    Cat.:
    U8964h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Tumor necrosis factor ligand superfamily member 4
    MSDS:
    Please sign in first.
    CLIA Kit for Human Tumor necrosis factor ligand superfamily member 4
    Cat.:
    U8964m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Tumor necrosis factor ligand superfamily member 4
    Cat.:
    P8964Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Tumor necrosis factor ligand superfamily member 4
    Polyclonal Antibody for Human Tumor necrosis factor ligand superfamily member 4
    Polyclonal Antibody for Human Tumor necrosis factor ligand superfamily member 4
    Cat.:
    P8964Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Tumor necrosis factor ligand superfamily member 4
    Monoclonal Antibody for Human Tumor necrosis factor ligand superfamily member 4
    Monoclonal Antibody for Human Tumor necrosis factor ligand superfamily member 4
    Monoclonal Antibody for Human Tumor necrosis factor ligand superfamily member 4
    Protein for Human Tumor necrosis factor ligand superfamily member 4
    Protein for Human Tumor necrosis factor ligand superfamily member 4
    Protein for Human Tumor necrosis factor ligand superfamily member 4
    Protein for Human Tumor necrosis factor ligand superfamily member 4

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    Linearity
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    References
    1. 1.
      "Molecular cloning and characterization of a novel glycoprotein, gp34, that is specifically induced by the human T-cell leukemia virus type I transactivator p40tax."
      Miura S. , Ohtani K. , Numata N. , Niki M. , Ohbo K. , Ina Y. , Gojobori T. , Tanaka Y. , Tozawa H. , Nakamura M. , Sugamura K.
      Mol. Cell. Biol.11:1313-1325(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Identification of a human OX-40 ligand, a costimulator of CD4+ T cells with homology to tumor necrosis factor."
      Godfrey W.R. , Fagnoni F.F. , Harara M.A. , Buck D. , Engleman E.G.
      J. Exp. Med.180:757-762(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    4. 4.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Testis.
    7. 7.
      "New variations in human OX40 ligand (CD134L) gene."
      Hikami K. , Tsuchiya N. , Tokunaga K.
      Genes Immun.1:521-522(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-67
    8. 8.
      "Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34."
      Baum P.R. , Gayle R.B. III , Ramsdell F. , Srinivasan S. , Sorensen R.A. , Watson M.L. , Seldin M.F. , Baker E. , Sutherland G.R. , Clifford K.N. , Alderson M.R. , Goodwin R.G. , Fanslow W.C.
      EMBO J.13:3992-4001(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
    9. 9.
      "Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus."
      Cunninghame Graham D.S. , Graham R.R. , Manku H. , Wong A.K. , Whittaker J.C. , Gaffney P.M. , Moser K.L. , Rioux J.D. , Altshuler D. , Behrens T.W. , Vyse T.J.
      Nat. Genet.40:83-89(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN SUSCEPTIBILITY TO SLE
    10. 10.
      "The crystal structure of the costimulatory OX40-OX40L complex."
      Compaan D.M. , Hymowitz S.G.
      Structure14:1321-1330(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.41 ANGSTROMS) OF 48-183 IN COMPLEX WITH TNFRSF4;SUBUNIT;DISULFIDE BOND;GLYCOSYLATION AT ASN-152
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