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Index > Protein center > UGDH(Gene name) > Human
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  • UGDH (Gene name),
  • UDP-glucose 6-dehydrogenase (Protein name ),  UGDH_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    UGDH;
    Protein name:
    UDP-glucose 6-dehydrogenase(UDP-Glc dehydrogenase;UDP-GlcDH;UDPGDH);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homohexamer.
    Function:
    Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    494
    Sequence:
    50:
    MFEIKKICCI | GAGYVGGPTC | SVIAHMCPEI | RVTVVDVNES | RINAWNSPTL | 
    100:
    PIYEPGLKEV | VESCRGKNLF | FSTNIDDAIK | EADLVFISVN | TPTKTYGMGK | 
    150:
    GRAADLKYIE | ACARRIVQNS | NGYKIVTEKS | TVPVRAAESI | RRIFDANTKP | 
    200:
    NLNLQVLSNP | EFLAEGTAIK | DLKNPDRVLI | GGDETPEGQR | AVQALCAVYE | 
    250:
    HWVPREKILT | TNTWSSELSK | LAANAFLAQR | ISSINSISAL | CEATGADVEE | 
    300:
    VATAIGMDQR | IGNKFLKASV | GFGGSCFQKD | VLNLVYLCEA | LNLPEVARYW | 
    350:
    QQVIDMNDYQ | RRRFASRIID | SLFNTVTDKK | IAILGFAFKK | DTGDTRESSS | 
    400:
    IYISKYLMDE | GAHLHIYDPK | VPREQIVVDL | SHPGVSEDDQ | VSRLVTISKD | 
    450:
    PYEACDGAHA | VVICTEWDMF | KELDYERIHK | KMLKPAFIFD | GRRVLDGLHN | 
    494:
    ELQTIGFQIE | TIGKKVSSKR | IPYAPSGEIP | KFSLQDPPNK | KPKV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    MIM:
    SMR:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human UDP-Glc dehydrogenase
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    E12968r
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    ELISA Kit for Human UDP-Glc dehydrogenase
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    E12968m
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    ELISA Kit for Human UDP-Glc dehydrogenase
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    E12968b
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    ELISA Kit for Human UDP-Glc dehydrogenase
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    E12968c
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    ELISA Kit for Human UDP-Glc dehydrogenase
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    E12968h
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    CLIA Kit for Human UDP-Glc dehydrogenase
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    U12968b
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    CLIA Kit for Human UDP-Glc dehydrogenase
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    U12968m
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    CLIA Kit for Human UDP-Glc dehydrogenase
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    U12968c
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    CLIA Kit for Human UDP-Glc dehydrogenase
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    U12968h
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    CLIA Kit for Human UDP-Glc dehydrogenase
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    U12968r
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    Polyclonal Antibody for Human UDP-Glc dehydrogenase
    Polyclonal Antibody for Human UDP-Glc dehydrogenase
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    P12968Rb-h
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    40ug/0.2ml
    Polyclonal Antibody for Human UDP-Glc dehydrogenase
    Polyclonal Antibody for Human UDP-Glc dehydrogenase
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    P12968Rb-r
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    Packing:
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    Polyclonal Antibody for Human UDP-Glc dehydrogenase
    Cat.:
    P12968Rb-m
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human UDP-Glc dehydrogenase
    Monoclonal Antibody for Human UDP-Glc dehydrogenase
    Monoclonal Antibody for Human UDP-Glc dehydrogenase
    Monoclonal Antibody for Human UDP-Glc dehydrogenase
    Monoclonal Antibody for Human UDP-Glc dehydrogenase
    Protein for Human UDP-Glc dehydrogenase
    Protein for Human UDP-Glc dehydrogenase
    Protein for Human UDP-Glc dehydrogenase
    Protein for Human UDP-Glc dehydrogenase
    Protein for Human UDP-Glc dehydrogenase

    R&D Technical Data
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    Precision
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    Linearity
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    References
    1. 1.
      "Molecular cloning and characterization of the human and mouse UDP-glucose dehydrogenase genes."
      Spicer A.P. , Kaback L.A. , Smith T.J. , Seldin M.F.
      J. Biol. Chem.273:25117-25124(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Placenta.
    2. 2.
      "cDNA cloning and expression analysis of the human UDPglucose dehydrogenase."
      Peng H.L. , Lou M.D. , Chang M.L. , Chang H.Y.
      Proc. Natl. Sci. Counc. Repub. China, B, Life Sci.22:166-172(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
      tissue: Liver.
    3. 3.
      "Characterization of human gene encoding UDP-glucose dehydrogenase."
      Chang M.L. , Chang H.Y. , Peng H.L.
      Submitted (2000-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3)
      tissue: Thymus.
    5. 5.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Skin.
    8. 8.
      Raghuram V. , Foskett J.K.
      Submitted (1998-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 214-388 (ISOFORM 1/2/3)
    9. 9.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-107;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      "Structural and kinetic evidence that catalytic reaction of human UDP-glucose 6-dehydrogenase involves covalent thiohemiacetal and thioester enzyme intermediates."
      Egger S. , Chaikuad A. , Klimacek M. , Kavanagh K.L. , Oppermann U. , Nidetzky B.
      J. Biol. Chem.287:2119-2129(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 1-466;ACTIVE SITE
    13. 13.
      "Conformational flexibility in the allosteric regulation of human UDP-alpha-D-glucose 6-dehydrogenase."
      Sennett N.C. , Kadirvelraj R. , Wood Z.A.
      Biochemistry50:9651-9663(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS);SUBUNIT;ENZYME REGULATION;ALLOSTERIC REGULATION
    14. 14.
      "Structure and mechanism of human UDP-glucose 6-dehydrogenase."
      Egger S. , Chaikuad A. , Kavanagh K.L. , Oppermann U. , Nidetzky B.
      J. Biol. Chem.286:23877-23887(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 1-466 IN COMPLEX WITH NAD; UDP-GLUCOSE AND UDP-GLUCURONATE;SUBUNIT;ACTIVE SITE
    15. 15.
      "Structural basis of cooperativity in human UDP-glucose dehydrogenase."
      Rajakannan V. , Lee H.S. , Chong S.H. , Ryu H.B. , Bae J.Y. , Whang E.Y. , Huh J.W. , Cho S.W. , Kang L.W. , Choe H. , Robinson R.C.
      PLoS ONE6:E25226-E25226(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 1-487 IN COMPLEX WITH UDP-GLUCOSE;SUBUNIT;ACTIVE SITE
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