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Index > Protein center > VDAC1(Gene name) > Rabbit
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  • VDAC1 (Gene name),
  • Voltage-dependent anion-selective channel protein 1 (Protein name ),  VDAC1_RABIT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    VDAC1;
    Protein name:
    Voltage-dependent anion-selective channel protein 1(VDAC-1);
    Alternative:
    Outer mitochondrial membrane protein porin 1;
    Organism:
    Rabbit (Oryctolagus cuniculus). 
    General Annotation
    Sub Unit:
    Interacts with hexokinases (By similarity). Interacts with BCL2L1.
    Function:
    Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
    Subcellular Location:
    Mitochondrion outer membrane Cell membrane
    Protein Attributes:
    Sequence length:
    283
    Sequence:
    50:
    MAVPPTYADL | GKSARDVFTK | GYGFGLIKLD | LKTKSENGLE | FTSSGSANTE | 
    100:
    TTKVTGSLET | KYRWTEYGLT | FTEKWNTDNT | LGTEITVEDQ | LARGLKLTFD | 
    150:
    SSFSPNTGKK | NAKIKTGYKR | EHINLGCDVD | FDIAGPSIRG | ALVLGYEGWL | 
    200:
    AGYQMNFETA | KSRVTQSNFA | VGYKTDEFQL | HTNVNDGTEF | GGSIYQKVNK | 
    250:
    KLETAVNLAW | TAGNSNTRFG | IAAKYQIDPD | ACFSAKVNNS | SLIGLGYTQT | 
    283:
    LKPGIKLTLS | ALLDGKNVNA | GGHKLGLGLE | FQA
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    String:
    UniGene:
    Uniprot:
     
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    U12942p
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    Packing:
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    Monoclonal Antibody for Rabbit VDAC-1
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    Monoclonal Antibody for Rabbit VDAC-1
    Monoclonal Antibody for Rabbit VDAC-1
    Protein for Rabbit VDAC-1
    Protein for Rabbit VDAC-1
    Protein for Rabbit VDAC-1
    Protein for Rabbit VDAC-1
    Protein for Rabbit VDAC-1
    Protein for Rabbit VDAC-1

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    References
    1. 1.
      Rae J.L.
      Submitted (1999-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: New Zealand white.
      tissue: Corneal endothelium.
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