Protein name:
Voltage-dependent anion-selective channel protein 1 (VDAC-1) ;
Alternative:
Outer mitochondrial membrane protein porin 1 ;
Organism:
Rabbit (Oryctolagus cuniculus).
General Annotation
Sub Unit:
Interacts with hexokinases (By similarity). Interacts with BCL2L1.
Function:
Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
Subcellular Location:
Mitochondrion outer membrane
Cell membrane
Protein Attributes:
50:
MAVPPTYADL | GKSARDVFTK | GYGFGLIKLD | LKTKSENGLE | FTSSGSANTE |
100:
TTKVTGSLET | KYRWTEYGLT | FTEKWNTDNT | LGTEITVEDQ | LARGLKLTFD |
150:
SSFSPNTGKK | NAKIKTGYKR | EHINLGCDVD | FDIAGPSIRG | ALVLGYEGWL |
200:
AGYQMNFETA | KSRVTQSNFA | VGYKTDEFQL | HTNVNDGTEF | GGSIYQKVNK |
250:
KLETAVNLAW | TAGNSNTRFG | IAAKYQIDPD | ACFSAKVNNS | SLIGLGYTQT |
283:
LKPGIKLTLS | ALLDGKNVNA | GGHKLGLGLE | FQA
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rabbit
Human
Rat
Mouse
Bovine
Pig
ELISA Kit for Rabbit VDAC-1
ELISA Kit for Rabbit VDAC-1
ELISA Kit for Rabbit VDAC-1
ELISA Kit for Rabbit VDAC-1
ELISA Kit for Rabbit VDAC-1
ELISA Kit for Rabbit VDAC-1
CLIA Kit for Rabbit VDAC-1
CLIA Kit for Rabbit VDAC-1
CLIA Kit for Rabbit VDAC-1
CLIA Kit for Rabbit VDAC-1
CLIA Kit for Rabbit VDAC-1
CLIA Kit for Rabbit VDAC-1
Polyclonal Antibody for Rabbit VDAC-1
Polyclonal Antibody for Rabbit VDAC-1
Polyclonal Antibody for Rabbit VDAC-1
Polyclonal Antibody for Rabbit VDAC-1
Polyclonal Antibody for Rabbit VDAC-1
Polyclonal Antibody for Rabbit VDAC-1
Monoclonal Antibody for Rabbit VDAC-1
Monoclonal Antibody for Rabbit VDAC-1
Monoclonal Antibody for Rabbit VDAC-1
Monoclonal Antibody for Rabbit VDAC-1
Monoclonal Antibody for Rabbit VDAC-1
Monoclonal Antibody for Rabbit VDAC-1
Protein for Rabbit VDAC-1
Protein for Rabbit VDAC-1
Protein for Rabbit VDAC-1
Protein for Rabbit VDAC-1
Protein for Rabbit VDAC-1
Protein for Rabbit VDAC-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
Rae J.L.
Submitted (1999-12) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
New Zealand white .
tissue :
Corneal endothelium .