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Index > Protein center > WIBG(Gene name) > Bovine
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  • WIBG (Gene name),
  • Partner of Y14 and mago (Protein name ),  WIBG_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    WIBG(PYM);
    Protein name:
    Partner of Y14 and mago;
    Alternative:
    Protein wibg homolog;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Interacts (via N-terminus) with MAGOH and RBM8A; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.
    Function:
    Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions.
    Subcellular Location:
    Cytoplasm Nucleus nucleolus Nucleus nucleoplasm Shuttles between the nucleus and the cytoplasm. Nuclear export is mediated by XPO1/CRM1.
    Protein Attributes:
    Sequence length:
    203
    Sequence:
    50:
    MATPYVTDET | GGKYIASTQR | PDGTWRKQRR | VKEGYVPQEE | VPVYENKYVK | 
    100:
    FFKSKPELPP | GLSPEATAPI | TASRPEGGEP | ALSKTAKRNL | KRKEKRRQQQ | 
    150:
    EKGEAEALSR | TLEKVSLGET | AQVPSAPQAS | RAAPTAASDQ | PDSAATTEKA | 
    200:
    KKIKNLKKKL | RQVEELQQRI | QAGEISQPSK | EQLEKLARRR | ALEEELEDLE | 
    203:
    LGL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Partner of Y14 and mago
    ELISA Kit for Bovine Partner of Y14 and mago
    ELISA Kit for Bovine Partner of Y14 and mago
    CLIA Kit for Bovine Partner of Y14 and mago
    CLIA Kit for Bovine Partner of Y14 and mago
    CLIA Kit for Bovine Partner of Y14 and mago
    Polyclonal Antibody for Bovine Partner of Y14 and mago
    Polyclonal Antibody for Bovine Partner of Y14 and mago
    Polyclonal Antibody for Bovine Partner of Y14 and mago
    Monoclonal Antibody for Bovine Partner of Y14 and mago
    Monoclonal Antibody for Bovine Partner of Y14 and mago
    Monoclonal Antibody for Bovine Partner of Y14 and mago
    Protein for Bovine Partner of Y14 and mago
    Protein for Bovine Partner of Y14 and mago
    Protein for Bovine Partner of Y14 and mago

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2007-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Fetal liver.
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