Gene name:
XBP1 (TREB5;XBP2) ;
Protein name:
X-box-binding protein 1 (XBP-1) ;
Alternative:
Tax-responsive element-binding protein 5 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by activating unfolded protein response (UPR) target genes via direct binding to the UPR element (UPRE). Binds DNA preferably to the CRE-like element 5'-GATGACGTG[TG]N(3)[AT]T-3', and also to some TPA response elements (TRE). Binds to the HLA DR-alpha promoter. Binds to the Tax-responsive element (TRE) of HTLV-I.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MVVVAAAPNP | ADGTPKVLLL | SGQPASAAGA | PAGQALPLMV | PAQRGASPEA |
100:
ASGGLPQARK | RQRLTHLSPE | EKALRRKLKN | RVAAQTARDR | KKARMSELEQ |
150:
QVVDLEEENQ | KLLLENQLLR | EKTHGLVVEN | QELRQRLGMD | ALVAEEEAEA |
200:
KGNEVRPVAG | SAESAALRLR | APLQQVQAQL | SPLQNISPWI | LAVLTLQIQS |
250:
LISCWAFWTT | WTQSCSSNAL | PQSLPAWRSS | QRSTQKDPVP | YQPPFLCQWG |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
ELISA Kit for Human XBP-1
ELISA Kit for Human XBP-1
ELISA Kit for Human XBP-1
ELISA Kit for Human XBP-1
Polyclonal Antibody for Human XBP-1
Polyclonal Antibody for Human XBP-1
Polyclonal Antibody for Human XBP-1
Polyclonal Antibody for Human XBP-1
Monoclonal Antibody for Human XBP-1
Monoclonal Antibody for Human XBP-1
Monoclonal Antibody for Human XBP-1
Monoclonal Antibody for Human XBP-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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