In the early diagnosis of diabetes in the treatment and prognosis of shows an important role, Ⅰ diabetes (T1DM) is due to autoimmune injury islet beta cells, thus reduce insulin sensitivity or reduce the secretion disease, including insulin autoantibody (IAA) is a very important indicator. IAA is an antibody to endogenous insulin and the only specific antibody to islet beta cells. In diabetic autoantibodies, IAA appears earliest and lasts for a short time. Most of IAA combines with insulin to make it lose its biological activity, so the measurement of IAA can provide an important basis for the treatment of diabetes, and is also an ideal indicator for the evaluation of insulin. The positive rate of IAA in classic T1DM patients can reach 65%, which has a good sensitivity to the diagnosis of T1DM. Currently, the enzyme linked immunoassay is mainly used to detect IAA.
E1264h produced by Wuhan EIAAB technology co., LTD. is a microwave strip plate ELISA (enzyme-linked immunosorbent assay) kit available for the analysis of the presence of lysins and metalo proteinases 30(insulin autoantibody) in biological samples. The concentration gradient of the standard or positive control product of the kit provides theoretical kit detection range for biological study samples containing insulin autoantibodies. The E1264h kit ELISA was used to detect the target of insulin autoantibody antigen in the samples based on the antibody - insulin autoantibody antigen interaction (immunoadsorption) and the HRP colorimetric detection system.
Product link:
https://www.eiaab.com.cn/product-detail/elisa_kit/10109_eiaab/