Ppp2r2d ELISA Kit for Mouse(Mus musculus) | EIAab.comPpp2r2d ELISA Kit for Mouse(Mus musculus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Ppp2r2d(Gene name) > Mouse

Ppp2r2d (Gene name),

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (Protein name ), 2ABD_MOUSE from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Ppp2r2d(D7Ertd753e;Kiaa1541);

Protein name:

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform;

Alternative:

PP2A subunit B isoform PR55-delta;PP2A subunit B isoform B55-delta;PP2A subunit B isoform delta;PP2A subunit B isoform R2-delta;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Interacts with ENSA (when phosphorylated at 'Ser-67') and ARPP19 (when phosphorylated at 'Ser-62'), leading to inhibit PP2A activity.

Function:

B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

453

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

453:

KIN

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

SMR:

Q925E7

UniGene:

Mm.258739

Pfam:

PF00400

KEGG:

mmu:52432

String:

Q925E7

Uniprot:

Q925E7

FOR

ELISA Kit for Mouse Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

CLIA Kit for Mouse Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

Polyclonal Antibody for Mouse Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

Monoclonal Antibody for Mouse Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

Protein for Mouse Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Analysis of mDRA (Mouse Down-regulated in Adenoma) interaction in yeast two-hybrid system."
Chang H. , Lee S. , Park K.
Submitted (2001-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: C57BL/6J.
2.

"Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Koseki H. , Hiraoka S. , Saga Y. , Nagase T. , Ohara O. , Koga H.
DNA Res.10:167-180(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Natural killer cell.
3.

Okazaki N. , Kikuno R. , Nagase T. , Ohara O. , Koga H.
Submitted (2004-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
tissue: Brain.

Product Feedback Wall

* Email:
*Comments: