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Index > Protein center > NT5E(Gene name) > Human
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  • NT5E (Gene name),
  • 5'-nucleotidase (Protein name ),  5NTD_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    NT5E(NT5;NTE);
    Protein name:
    5'-nucleotidase(5'-NT);
    Alternative:
    Ecto-5'-nucleotidase;
    CD:
    CD73;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked.
    Function:
    Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor
    Protein Attributes:
    Sequence length:
    574
    Sequence:
    50:
    MCPRAARAPA | TLLLALGAVL | WPAAGAWELT | ILHTNDVHSR | LEQTSEDSSK | 
    100:
    CVNASRCMGG | VARLFTKVQQ | IRRAEPNVLL | LDAGDQYQGT | IWFTVYKGAE | 
    150:
    VAHFMNALRY | DAMALGNHEF | DNGVEGLIEP | LLKEAKFPIL | SANIKAKGPL | 
    200:
    ASQISGLYLP | YKVLPVGDEV | VGIVGYTSKE | TPFLSNPGTN | LVFEDEITAL | 
    250:
    QPEVDKLKTL | NVNKIIALGH | SGFEMDKLIA | QKVRGVDVVV | GGHSNTFLYT | 
    300:
    GNPPSKEVPA | GKYPFIVTSD | DGRKVPVVQA | YAFGKYLGYL | KIEFDERGNV | 
    350:
    ISSHGNPILL | NSSIPEDPSI | KADINKWRIK | LDNYSTQELG | KTIVYLDGSS | 
    400:
    QSCRFRECNM | GNLICDAMIN | NNLRHTDEMF | WNHVSMCILN | GGGIRSPIDE | 
    450:
    RNNGTITWEN | LAAVLPFGGT | FDLVQLKGST | LKKAFEHSVH | RYGQSTGEFL | 
    500:
    QVGGIHVVYD | LSRKPGDRVV | KLDVLCTKCR | VPSYDPLKMD | EVYKVILPNF | 
    550:
    LANGGDGFQM | IKDELLRHDS | GDQDINVVST | YISKMKVIYP | AVEGRIKFST | 
    574:
    GSHCHGSFSL | IFLSLWAVIF | VLYQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    MIM:
    KEGG:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human 5'-NT
    Cat.:
    E0104m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human 5'-NT
    Cat.:
    E0104r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human 5'-NT
    Cat.:
    E0104h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human 5'-NT
    Cat.:
    E0104b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 5'-NT
    Cat.:
    U0104h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human 5'-NT
    Cat.:
    U0104m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 5'-NT
    Cat.:
    U0104r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 5'-NT
    Cat.:
    U0104b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human 5'-NT
    Cat.:
    P0104Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human 5'-NT
    Cat.:
    P0104Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human 5'-NT
    Polyclonal Antibody for Human 5'-NT
    Cat.:
    P0104Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human 5'-NT
    Monoclonal Antibody for Human 5'-NT
    Monoclonal Antibody for Human 5'-NT
    Monoclonal Antibody for Human 5'-NT
    Protein for Human 5'-NT
    Protein for Human 5'-NT
    Protein for Human 5'-NT
    Protein for Human 5'-NT

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Primary structure of human placental 5'-nucleotidase and identification of the glycolipid anchor in the mature form."
      Misumi Y. , Ogata S. , Ohkubo K. , Hirose S. , Ikehara Y.
      Eur. J. Biochem.191:563-569(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE;GPI-ANCHOR AT SER-549
      tissue: Placenta.
    2. 2.
      "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
      Otsuki T. , Ota T. , Nishikawa T. , Hayashi K. , Suzuki Y. , Yamamoto J. , Wakamatsu A. , Kimura K. , Sakamoto K. , Hatano N. , Kawai Y. , Ishii S. , Saito K. , Kojima S. , Sugiyama T. , Ono T. , Okano K. , Yoshikawa Y. , more...
      DNA Res.12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    3. 3.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "Isolation and characterization of the promoter of the human 5'-nucleotidase (CD73)-encoding gene."
      Hansen K.R. , Resta R. , Webb C.F. , Thompson L.F.
      Gene167:307-312(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-113
      tissue: Placenta.
    5. 5.
      Zanoni L. , Rosi F. , Pagani R. , Marinello E.
      Submitted (1998-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 359-489;VARIANT ALA-376
      tissue: Leukocyte.
    6. 6.
      "Characterization of soluble vs membrane-bound human placental 5'-nucleotidase."
      Klemens M.R. , Sherman W.R. , Holmberg N.J. , Ruedi J.M. , Low M.G. , Thompson L.F.
      Biochem. Biophys. Res. Commun.172:1371-1377(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 27-40
      tissue: Placenta.
    7. 7.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-311; ASN-333 AND ASN-403
      tissue: Liver.
    8. 8.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-333
      tissue: Leukemic T-cell.
    9. 9.
      "The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism."
      Garavaglia S. , Bruzzone S. , Cassani C. , Canella L. , Allegrone G. , Sturla L. , Mannino E. , Millo E. , De Flora A. , Rizzi M.
      Biochem. J.441:131-141(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBSTRATE SPECIFICITY
    10. 10.
      "Crystal structure of the human ecto-5'-nucleotidase (CD73): insights into the regulation of purinergic signaling."
      Knapp K. , Zebisch M. , Pippel J. , El-Tayeb A. , Muller C.E. , Strater N.
      Structure20:2161-2173(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.58 ANGSTROMS) OF 27-549 IN COMPLEXES WITH ATP ANALOG AND ZINC IONS;SUBUNIT;GLYCOSYLATION AT ASN-311;DISULFIDE BONDS
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CALJA TYR-358
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