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Index > Protein center > GOT2(Gene name) > Human
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  • GOT2 (Gene name),
  • Aspartate aminotransferase, mitochondrial (Protein name ),  AATM_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GOT2;
    Protein name:
    Aspartate aminotransferase, mitochondrial(mAspAT);
    Alternative:
    Glutamate oxaloacetate transaminase 2;Fatty acid-binding protein(FABP-1);Transaminase A;Plasma membrane-associated fatty acid-binding protein(FABPpm);Kynurenine--oxoglutarate transaminase IV;Kynurenine--oxoglutarate transaminase 4;Transaminase A;Plasma membrane-associated fatty acid-binding protein(FABPpm);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids.
    Subcellular Location:
    Mitochondrion matrix Cell membrane Exposure to alcohol promotes translocation to the cell membrane.
    Protein Attributes:
    Sequence length:
    430
    Sequence:
    50:
    MALLHSGRVL | PGIAAAFHPG | LAAAASARAS | SWWTHVEMGP | PDPILGVTEA | 
    100:
    FKRDTNSKKM | NLGVGAYRDD | NGKPYVLPSV | RKAEAQIAAK | NLDKEYLPIG | 
    150:
    GLAEFCKASA | ELALGENSEV | LKSGRFVTVQ | TISGTGALRI | GASFLQRFFK | 
    200:
    FSRDVFLPKP | TWGNHTPIFR | DAGMQLQGYR | YYDPKTCGFD | FTGAVEDISK | 
    250:
    IPEQSVLLLH | ACAHNPTGVD | PRPEQWKEIA | TVVKKRNLFA | FFDMAYQGFA | 
    300:
    SGDGDKDAWA | VRHFIEQGIN | VCLCQSYAKN | MGLYGERVGA | FTMVCKDADE | 
    350:
    AKRVESQLKI | LIRPMYSNPP | LNGARIAAAI | LNTPDLRKQW | LQEVKVMADR | 
    400:
    IIGMRTQLVS | NLKKEGSTHN | WQHITDQIGM | FCFTGLKPEQ | VERLIKEFSI | 
    430:
    YMTKDGRISV | AGVTSSNVGY | LAHAIHQVTK | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    KEGG:
    UniGene:
    String:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human mAspAT
    Cat.:
    E1612h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human mAspAT
    Cat.:
    E1612p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human mAspAT
    Cat.:
    E1612m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    ELISA Kit for Human mAspAT
    Cat.:
    E1612r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human mAspAT
    MSDS:
    Please sign in first.
    ELISA Kit for Human mAspAT
    Cat.:
    E1612b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human mAspAT
    Cat.:
    E1612c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human mAspAT
    Cat.:
    U1612c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human mAspAT
    Cat.:
    U1612m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human mAspAT
    Cat.:
    U1612r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human mAspAT
    MSDS:
    Please sign in first.
    CLIA Kit for Human mAspAT
    Cat.:
    U1612b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human mAspAT
    Cat.:
    U1612p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human mAspAT
    Cat.:
    U1612h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human mAspAT
    Cat.:
    P1612Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human mAspAT
    Polyclonal Antibody for Human mAspAT
    Cat.:
    P1612Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human mAspAT
    Polyclonal Antibody for Human mAspAT
    Polyclonal Antibody for Human mAspAT
    Polyclonal Antibody for Human mAspAT
    Cat.:
    P1612Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human mAspAT
    Monoclonal Antibody for Human mAspAT
    Monoclonal Antibody for Human mAspAT
    Monoclonal Antibody for Human mAspAT
    Monoclonal Antibody for Human mAspAT
    Monoclonal Antibody for Human mAspAT
    Monoclonal Antibody for Human mAspAT
    Protein for Human mAspAT
    Protein for Human mAspAT
    Protein for Human mAspAT
    Protein for Human mAspAT
    Protein for Human mAspAT
    Protein for Human mAspAT
    Protein for Human mAspAT

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    References
    1. 1.
      "Nucleotide sequence and tissue distribution of the human mitochondrial aspartate aminotransferase mRNA."
      Pol S. , Bousquet-Lemercier B. , Pave-Preux M. , Pawlak A. , Nalpas B. , Berthelot P. , Hanoune J. , Barouki R.
      Biochem. Biophys. Res. Commun.157:1309-1315(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT GLY-346
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT GLY-346
      tissue: Subthalamic nucleus.
    3. 3.
      Suzuki Y. , Sugano S. , Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S.
      Submitted (2005-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Gastric mucosa.
    4. 4.
      "The sequence and analysis of duplication-rich human chromosome 16."
      Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
      Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT ALA-428
      tissue: Muscle.
    6. 6.
      "The primary structure of mitochondrial aspartate aminotransferase from human heart."
      Martini F. , Angelaccio S. , Barra D. , Pascarella S. , Maras B. , Doonan S. , Bossa F.
      Biochim. Biophys. Acta832:46-51(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 30-430;VARIANT GLY-346
    7. 7.
      "Ethanol up-regulates fatty acid uptake and plasma membrane expression and export of mitochondrial aspartate aminotransferase in HepG2 cells."
      Zhou S.L. , Gordon R.E. , Bradbury M. , Stump D. , Kiang C.L. , Berk P.D.
      Hepatology27:1064-1074(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INDUCTION;SUBCELLULAR LOCATION
    8. 8.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-73; LYS-90; LYS-159; LYS-234; LYS-296; LYS-396 AND LYS-404;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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