Gene name:
ABCA2 (ABC2;KIAA1062) ;
Protein name:
ATP-binding cassette sub-family A member 2 ;
Alternative:
ATP-binding cassette transporter 2 (ATP-binding cassette 2) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development.
Subcellular Location:
Endosome
Membrane
Multi-pass membrane protein
Lysosome
Membrane
Multi-pass membrane protein
Forms discrete, punctate intracellular vesicles.
Protein Attributes:
50:
MGFLHQLQLL | LWKNVTLKRR | SPWVLAFEIF | IPLVLFFILL | GLRQKKPTIS |
100:
VKEAFYTAAP | LTSAGILPVM | QSLCPDGQRD | EFGFLQYANS | TVTQLLERLD |
150:
RVVEEGNLFD | PARPSLGSEL | EALRQHLEAL | SAGPGTSGSH | LDRSTVSSFS |
200:
LDSVARNPQE | LWRFLTQNLS | LPNSTAQALL | AARVDPPEVY | HLLFGPSSAL |
250:
DSQSGLHKGQ | EPWSRLGGNP | LFRMEELLLA | PALLEQLTCT | PGSGELGRIL |
300:
TVPESQKGAL | QGYRDAVCSG | QAAARARRFS | GLSAELRNQL | DVAKVSQQLG |
350:
LDAPNGSDSS | PQAPPPRRLQ | ALLGDLLDAQ | KVLQDVDVLS | ALALLLPQGA |
400:
CTGRTPGPPA | SGAGGAANGT | GAGAVMGPNA | TAEEGAPSAA | ALATPDTLQG |
450:
QCSAFVQLWA | GLQPILCGNN | RTIEPEALRR | GNMSSLGFTS | KEQRNLGLLV |
500:
HLMTSNPKIL | YAPAGSEVDR | VILKANETFA | FVGNVTHYAQ | VWLNISAEIR |
550:
SFLEQGRLQQ | HLRWLQQYVA | ELRLHPEALN | LSLDELPPAL | RQDNFSLPSG |
600:
MALLQQLDTI | DNAACGWIQF | MSKVSVDIFK | GFHDEESIVN | YTLNQAYQDN |
650:
VTVFASVIFQ | TRKDGSLPPH | VHYKIRQNSS | FTEKTNEIRR | AYWRPGPNTG |
700:
GRFYFLYGFV | WIQDMMERAI | IDTFVGHDVV | EPGSYVQMFP | YPCYTRDDFL |
750:
FVIEHMMPLC | MVISWVYSVA | MTIQHIVAEK | EHRLKEVMKT | MGLNNAVHWV |
800:
AWFITGFVQL | SISVTALTAI | LKYGQVLMHS | HVVIIWLFLA | VYAVATIMFC |
850:
FLVSVLYSKA | KLASACGGII | YFLSYVPYMY | VAIREEVAHD | KITAFEKCIA |
900:
SLMSTTAFGL | GSKYFALYEV | AGVGIQWHTF | SQSPVEGDDF | NLLLAVTMLM |
950:
VDAVVYGILT | WYIEAVHPGM | YGLPRPWYFP | LQKSYWLGSG | RTEAWEWSWP |
1000:
WARTPRLSVM | EEDQACAMES | RRFEETRGME | EEPTHLPLVV | CVDKLTKVYK |
1050:
DDKKLALNKL | SLNLYENQVV | SFLGHNGAGK | TTTMSILTGL | FPPTSGSATI |
1100:
YGHDIRTEMD | EIRKNLGMCP | QHNVLFDRLT | VEEHLWFYSR | LKSMAQEEIR |
1150:
REMDKMIEDL | ELSNKRHSLV | QTLSGGMKRK | LSVAIAFVGG | SRAIILDEPT |
1200:
AGVDPYARRA | IWDLILKYKP | GRTILLSTHH | MDEADLLGDR | IAIISHGKLK |
1250:
CCGSPLFLKG | TYGDGYRLTL | VKRPAEPGGP | QEPGLASSPP | GRAPLSSCSE |
1300:
LQVSQFIRKH | VASCLLVSDT | STELSYILPS | EAAKKGAFER | LFQHLERSLD |
1350:
ALHLSSFGLM | DTTLEEVFLK | VSEEDQSLEN | SEADVKESRK | DVLPGAEGPA |
1400:
SGEGHAGNLA | RCSELTQSQA | SLQSASSVGS | ARGDEGAGYT | DVYGDYRPLF |
1450:
DNPQDPDNVS | LQEVEAEALS | RVGQGSRKLD | GGWLKVRQFH | GLLVKRFHCA |
1500:
RRNSKALFSQ | ILLPAFFVCV | AMTVALSVPE | IGDLPPLVLS | PSQYHNYTQP |
1550:
RGNFIPYANE | ERREYRLRLS | PDASPQQLVS | TFRLPSGVGA | TCVLKSPANG |
1600:
SLGPTLNLSS | GESRLLAARF | FDSMCLESFT | QGLPLSNFVP | PPPSPAPSDS |
1650:
PASPDEDLQA | WNVSLPPTAG | PEMWTSAPSL | PRLVREPVRC | TCSAQGTGFS |
1700:
CPSSVGGHPP | QMRVVTGDIL | TDITGHNVSE | YLLFTSDRFR | LHRYGAITFG |
1750:
NVLKSIPASF | GTRAPPMVRK | IAVRRAAQVF | YNNKGYHSMP | TYLNSLNNAI |
1800:
LRANLPKSKG | NPAAYGITVT | NHPMNKTSAS | LSLDYLLQGT | DVVIAIFIIV |
1850:
AMSFVPASFV | VFLVAEKSTK | AKHLQFVSGC | NPIIYWLANY | VWDMLNYLVP |
1900:
ATCCVIILFV | FDLPAYTSPT | NFPAVLSLFL | LYGWSITPIM | YPASFWFEVP |
1950:
SSAYVFLIVI | NLFIGITATV | ATFLLQLFEH | DKDLKVVNSY | LKSCFLIFPN |
2000:
YNLGHGLMEM | AYNEYINEYY | AKIGQFDKMK | SPFEWDIVTR | GLVAMAVEGV |
2050:
VGFLLTIMCQ | YNFLRRPQRM | PVSTKPVEDD | VDVASERQRV | LRGDADNDMV |
2100:
KIENLTKVYK | SRKIGRILAV | DRLCLGVRPG | ECFGLLGVNG | AGKTSTFKML |
2150:
TGDESTTGGE | AFVNGHSVLK | ELLQVQQSLG | YCPQCDALFD | ELTAREHLQL |
2200:
YTRLRGISWK | DEARVVKWAL | EKLELTKYAD | KPAGTYSGGN | KRKLSTAIAL |
2250:
IGYPAFIFLD | EPTTGMDPKA | RRFLWNLILD | LIKTGRSVVL | TSHSMEECEA |
2300:
LCTRLAIMVN | GRLRCLGSIQ | HLKNRFGDGY | MITVRTKSSQ | SVKDVVRFFN |
2350:
RNFPEAMLKE | RHHTKVQYQL | KSEHISLAQV | FSKMEQVSGV | LGIEDYSVSQ |
2400:
TTLDNVFVNF | AKKQSDNLEQ | QETEPPSALQ | SPLGCLLSLL | RPRSAPTELR |
2435:
ALVADEPEDL | DTEDEGLISF | EEERAQLSFN | TDTLC
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Mouse
ELISA Kit for Human ATP-binding cassette sub-family A member 2
ELISA Kit for Human ATP-binding cassette sub-family A member 2
ELISA Kit for Human ATP-binding cassette sub-family A member 2
CLIA Kit for Human ATP-binding cassette sub-family A member 2
CLIA Kit for Human ATP-binding cassette sub-family A member 2
CLIA Kit for Human ATP-binding cassette sub-family A member 2
Polyclonal Antibody for Human ATP-binding cassette sub-family A member 2
Polyclonal Antibody for Human ATP-binding cassette sub-family A member 2
Polyclonal Antibody for Human ATP-binding cassette sub-family A member 2
Monoclonal Antibody for Human ATP-binding cassette sub-family A member 2
Monoclonal Antibody for Human ATP-binding cassette sub-family A member 2
Monoclonal Antibody for Human ATP-binding cassette sub-family A member 2
Protein for Human ATP-binding cassette sub-family A member 2
Protein for Human ATP-binding cassette sub-family A member 2
Protein for Human ATP-binding cassette sub-family A member 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 3);VARIANT PRO-583
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);TISSUE SPECIFICITY;SUBCELLULAR LOCATION;VARIANT PRO-583
tissue :
Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 651-2435 (ISOFORM 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 665-2435 (ISOFORM 1)
tissue :
Brain .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1327 AND SER-1331;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-2412;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .