Acaca ELISA Kit for Rat(Rattus norvegicus) | EIAab.comAcaca ELISA Kit for Rat(Rattus norvegicus)

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Acaca (Gene name),

Acetyl-CoA carboxylase 1 (Protein name ), ACACA_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Acaca(Acac);

Protein name:

Acetyl-CoA carboxylase 1(ACC1);

Alternative:

ACC-alpha;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Monomer, homodimer, and homotetramer. Can form filamentous polymers. Interacts in its inactive phosphorylated form with the BRCT domains of BRCA1 which prevents ACACA dephosphorylation and inhibits lipid synthesis. Interacts with MID1IP1; interaction with MID1IP1 promotes oligomerization and increases its activity.

Function:

Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

2345

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2345:

KQIRSLVQAN | PEVAMDSIVH | MTQHISPTQR | AEVVRILSTM | DSPST

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10116.ENSRNOP00000050703

UniGene:

Rn.163753

Pfam:

PF08326

KEGG:

rno:60581

SMR:

P11497

String:

P11497

Uniprot:

P11497

FOR

ELISA Kit for Rat ACC1

Cat.:

E1284b

Price:

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Rat ACC1

Cat.:

E1284m

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Rat ACC1

Cat.:

E1284h

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Rat ACC1

Cat.:

E1284r

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Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Rat ACC1

Cat.:

U1284r

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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CLIA Kit for Rat ACC1

Cat.:

U1284m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat ACC1

Cat.:

U1284h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat ACC1

Cat.:

U1284b

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat ACC1

Cat.:

P1284Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat ACC1

Cat.:

P1284Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat ACC1

Cat.:

P1284Rb-r

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat ACC1

Monoclonal Antibody for Rat ACC1

Protein for Rat ACC1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Structure of the coding sequence and primary amino acid sequence of acetyl-coenzyme A carboxylase."
Lopez-Casillas F. , Bai D.-H. , Luo X. , Kong I.-S. , Hermodson M.A. , Kim K.-H.
Proc. Natl. Acad. Sci. U.S.A.85:5784-5788(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
2.

"Structural features of the acetyl-CoA carboxylase gene: mechanisms for the generation of mRNAs with 5' end heterogeneity."
Luo X.N. , Park K. , Lopez-Casillas F. , Kim K.-H.
Proc. Natl. Acad. Sci. U.S.A.86:4042-4046(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Fine-mapping and comprehensive transcript analysis reveals nonsynonymous variants within a novel 1.17 Mb blood pressure QTL region on rat chromosome 10."
Saad Y. , Garrett M.R. , Manickavasagam E. , Yerga-Woolwine S. , Farms P. , Radecki T. , Joe B.
Genomics89:343-353(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain: Dahl salt-sensitive.
strain: Lewis.
4.

"Heterogeneity at the 5' end of rat acetyl-coenzyme A carboxylase mRNA. Lipogenic conditions enhance synthesis of a unique mRNA in liver."
Lopez-Casillas F. , Kim K.-H.
J. Biol. Chem.264:7176-7184(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-33
5.

"Identification by amino acid sequencing of three major regulatory phosphorylation sites on rat acetyl-CoA carboxylase."
Munday M.R. , Campbell D.G. , Carling D. , Hardie D.G.
Eur. J. Biochem.175:331-338(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 76-85 AND 1198-1201;PHOSPHORYLATION AT SER-77; SER-79 AND SER-1200
6.

"Acetyl-CoA carboxylase mRNA species with or without inhibitory coding sequence for Ser-1200 phosphorylation."
Kong I.-S. , Lopez-Casillas F. , Kim K.-H.
J. Biol. Chem.265:13695-13701(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1167-1200 (ISOFORMS 1 AND 2);PHOSPHORYLATION AT SER-1200
7.

"Unique structural features and differential phosphorylation of the 280-kDa component (isozyme) of rat liver acetyl-CoA carboxylase."
Winz R. , Hess D. , Aebersold R. , Brownsey R.W.
J. Biol. Chem.269:14438-14445(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;IDENTIFICATION BY MASS SPECTROMETRY
strain: Wistar.
tissue: Liver.
8.

"Analysis of the biotin-binding site on acetyl-CoA carboxylase from rat."
Bai D.-H. , Moon T.-W. , Lopez-Casillas F. , Andrews P.C. , Kim K.-H.
Eur. J. Biochem.182:239-245(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: BIOTINYLATION AT LYS-785
9.

"Diurnal rhythm of phosphorylation of rat liver acetyl-CoA carboxylase by the AMP-activated protein kinase, demonstrated using freeze-clamping. Effects of high fat diets."
Davies S.P. , Carling D. , Munday M.R. , Hardie D.G.
Eur. J. Biochem.203:615-623(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-79; SER-1200 AND SER-1215
10.

"Phosphorylation of rat muscle acetyl-CoA carboxylase by AMP-activated protein kinase and protein kinase A."
Winder W.W. , Wilson H.A. , Hardie D.G. , Rasmussen B.B. , Hutber C.A. , Call G.B. , Clayton R.D. , Conley L.M. , Yoon S. , Zhou B.
J. Appl. Physiol.82:219-225(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION BY AMPK
11.

"Phosphoproteomic analysis of rat liver by high capacity IMAC and LC-MS/MS."
Moser K. , White F.M.
J. Proteome Res.5:98-104(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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