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Index > Protein center > DBI(Gene name) > Bovine
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  • DBI (Gene name),
  • Acyl-CoA-binding protein (Protein name ),  ACBP_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Vaild Sequence
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  • Gene name:
    DBI;
    Protein name:
    Acyl-CoA-binding protein(ACBP);
    Alternative:
    Endozepine(EP);Diazepam-binding inhibitor(DBI);
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    87
    Sequence:
    50:
    MSQAEFDKAA | EEVKHLKTKP | ADEEMLFIYS | HYKQATVGDI | NTERPGMLDF | 
    87:
    KGKAKWDAWN | ELKGTSKEDA | MKAYIDKVEE | LKKKYGI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine ACBP
    ELISA Kit for Bovine ACBP
    ELISA Kit for Bovine ACBP
    ELISA Kit for Bovine ACBP
    ELISA Kit for Bovine ACBP
    ELISA Kit for Bovine ACBP
    ELISA Kit for Bovine ACBP
    ELISA Kit for Bovine ACBP
    CLIA Kit for Bovine ACBP
    CLIA Kit for Bovine ACBP
    CLIA Kit for Bovine ACBP
    CLIA Kit for Bovine ACBP
    CLIA Kit for Bovine ACBP
    CLIA Kit for Bovine ACBP
    CLIA Kit for Bovine ACBP
    CLIA Kit for Bovine ACBP
    Polyclonal Antibody for Bovine ACBP
    Polyclonal Antibody for Bovine ACBP
    Polyclonal Antibody for Bovine ACBP
    Polyclonal Antibody for Bovine ACBP
    Polyclonal Antibody for Bovine ACBP
    Polyclonal Antibody for Bovine ACBP
    Polyclonal Antibody for Bovine ACBP
    Polyclonal Antibody for Bovine ACBP
    Monoclonal Antibody for Bovine ACBP
    Monoclonal Antibody for Bovine ACBP
    Monoclonal Antibody for Bovine ACBP
    Monoclonal Antibody for Bovine ACBP
    Monoclonal Antibody for Bovine ACBP
    Monoclonal Antibody for Bovine ACBP
    Monoclonal Antibody for Bovine ACBP
    Monoclonal Antibody for Bovine ACBP
    Protein for Bovine ACBP
    Protein for Bovine ACBP
    Protein for Bovine ACBP
    Protein for Bovine ACBP
    Protein for Bovine ACBP
    Protein for Bovine ACBP
    Protein for Bovine ACBP
    Protein for Bovine ACBP

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    References
    1. 1.
      "Bovine and human cDNA sequences encoding a putative benzodiazepine receptor ligand."
      Webb N.R. , Rose T.M. , Malik N. , Marquardt H. , Shoyab M. , Todaro G.J. , Lee D.C.
      DNA6:71-79(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2006-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Crossbred X Angus.
      tissue: Liver.
    3. 3.
      "Complete amino acid sequences of bovine and human endozepines. Homology with rat diazepam binding inhibitor."
      Marquardt H. , Todaro G.J. , Shoyab M.
      J. Biol. Chem.261:9727-9731(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-87;ACETYLATION AT SER-2
      tissue: Brain.
    4. 4.
      "Amino acid sequence of acyl-CoA-binding protein from cow liver."
      Mikkelsen J. , Hoejrup P. , Nielsen P.F. , Roepstorff P. , Knudsen J.
      Biochem. J.245:857-861(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-87
      tissue: Liver.
    5. 5.
      "Purification and characterization of variants of acyl-CoA-binding protein in the bovine liver."
      Jensen M.S. , Hoejrup P. , Rasmussen J.T. , Knudsen J.
      Biochem. J.284:809-812(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-87
      tissue: Liver.
    6. 6.
      "Acyl-CoA-binding protein (ACBP) localizes to the endoplasmic reticulum and Golgi in a ligand-dependent manner in mammalian cells."
      Hansen J.S. , Faergeman N.J. , Kragelund B.B. , Knudsen J.
      Biochem. J.410:463-472(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    7. 7.
      "The secondary structure in solution of acyl-coenzyme A binding protein from bovine liver using 1H nuclear magnetic resonance spectroscopy."
      Andersen K.V. , Ludvigsen S. , Mandrup S. , Knudsen J. , Poulsen F.M.
      Biochemistry30:10654-10663(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
    8. 8.
      "Three-dimensional structure in solution of acyl-coenzyme A binding protein from bovine liver."
      Andersen K.V. , Poulsen F.M.
      J. Mol. Biol.226:1131-1141(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
    9. 9.
      "The three-dimensional structure of acyl-coenzyme A binding protein from bovine liver: structural refinement using heteronuclear multidimensional NMR spectroscopy."
      Andersen K.V. , Poulsen F.M.
      J. Biomol. NMR3:271-284(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
    10. 10.
      "Three-dimensional structure of the complex between acyl-coenzyme A binding protein and palmitoyl-coenzyme A."
      Kragelund B.B. , Andersen K.V. , Madsen J.C. , Knudsen J. , Poulsen F.M.
      J. Mol. Biol.230:1260-1277(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR IN COMPLEX WITH THE ACYL-COA ANALOG COENZYME A AND PALMITIC ACID
    11. 11.
      "Binding site differences revealed by crystal structures of Plasmodium falciparum and bovine acyl-CoA binding protein."
      van Aalten D.M. , Milne K.G. , Zou J.Y. , Kleywegt G.J. , Bergfors T. , Ferguson M.A. , Knudsen J. , Jones T.A.
      J. Mol. Biol.309:181-192(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS);FUNCTION
    12. 12.
      "RDC-refined NMR structure of bovine acyl-coenzyme A binding protein, ACBP, in complex with palmitoyl-coenzyme A."
      Lerche M.H. , Kragelund B.B. , Redfield C. , Poulsen F.M.
      Submitted (2003-02) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR IN COMPLEX WITH THE ACYL-COA PALMITOYL-COENZYME A
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