Gene name:
    Accn1 (Asic2;Bnac1) ;
    
 
    Protein name:
    Amiloride-sensitive cation channel 1, neuronal ;
    
    Alternative:
    
    Amiloride-sensitive brain sodium channel ;Acid-sensing ion channel 2 ;Brain sodium channel 1 (BNC1;BNaC1) ;
    
    
 
    Organism:
        
        
        
        
        
        
    
        Mouse  (Mus musculus).  
    
 
General Annotation
    Sub Unit:
    Homotrimer or heterotrimer with other ASIC proteins (By similarity). Interacts with PRKCABP and ACCN3 (By similarity). Interacts with STOM.
    
 
    Function:
    Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.
    
 
    
        
        Subcellular Location:
        
    
     
     
      Cell membrane  
      Multi-pass membrane protein 
      
    Localized at the plasma membrane, in the soma and punctated peripheral processes of neurons. 
  
    
 
    
    Protein Attributes:
    
    50:
    MDLKESPSEG |  SLQPSSIQIF |  ANTSTLHGIR |  HIFVYGPLTI |  RRVLWAVAFV |  
    
 
    100:
    GSLGLLLVES |  SERVSYYFSY |  QHVTKVDEVV |  AQSLVFPAVT |  LCNLNGFRFS |  
    
 
    150:
    RLTTNDLYHA |  GELLALLDVN |  LQIPDPHLAD |  PTVLEALRQK |  ANFKHYKPKQ |  
    
 
    200:
    FSMLEFLHRV |  GHDLKDMMLY |  CKFKGQECGH |  QDFTTVFTKY |  GKCYMFNSGE |  
    
 
    250:
    DGKPLLTTVK |  GGTGNGLEIM |  LDIQQDEYLP |  IWGETEETTF |  EAGVKVQIHS |  
    
 
    300:
    QSEPPFIQEL |  GFGVAPGFQT |  FVATQEQRLT |  YLPPPWGECR |  SSEMGLDFFP |  
    
 
    350:
    VYSITACRID |  CETRYIVENC |  NCRMVHMPGD |  APFCTPEQHK |  ECAEPALGLL |  
    
 
    400:
    AEKDSNYCLC |  RTPCNLTRYN |  KELSMVKIPS |  KTSAKYLEKK |  FNKSEKYISE |  
    
 
    450:
    NILVLDIFFE |  ALNYETIEQK |  KAYEVAALLG |  DIGGQMGLFI |  GASILTILEL |  
    
 
    500:
    FDYIYELIKE |  KLLDLLGKEE |  EEGSHDENMS |  TCDTMPNHSE |  TISHTVNVPL |  
    
 
      Vaild Sequence:
    
 
Related Databases
Uniprot:
 
 
    
        
        ELISA Kit
         
        
        CLIA Kit
         
        
        Polyclonal Antibody
         
        
        Monoclonal Antibody
         
        
        Protein
         
        
     
FOR
    
        
        Rat
         
        
        Human
         
        
        Mouse
         
        
     
    
        ELISA Kit for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
    
        ELISA Kit for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
    
        ELISA Kit for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
    
        CLIA Kit for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
    
        CLIA Kit for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
    
        CLIA Kit for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
    
        Protein for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
    
        Protein for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
    
        Protein for Mouse Amiloride-sensitive cation channel 1, neuronal
        
     
    
    
    
    
    
    
 
 
 
 
 
 
 
 
    R&D Technical Data
    
    
    
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    Precision
    
    
    
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    Linearity
    
    
    
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